713 related articles for article (PubMed ID: 29614232)
1. On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA.
Kulkarni JA; Darjuan MM; Mercer JE; Chen S; van der Meel R; Thewalt JL; Tam YYC; Cullis PR
ACS Nano; 2018 May; 12(5):4787-4795. PubMed ID: 29614232
[TBL] [Abstract][Full Text] [Related]
2. Characterization of Lipid Nanoparticles Containing Ionizable Cationic Lipids Using Design-of-Experiments Approach.
Terada T; Kulkarni JA; Huynh A; Chen S; van der Meel R; Tam YYC; Cullis PR
Langmuir; 2021 Jan; 37(3):1120-1128. PubMed ID: 33439022
[TBL] [Abstract][Full Text] [Related]
3. Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads.
Kulkarni JA; Witzigmann D; Leung J; van der Meel R; Zaifman J; Darjuan MM; Grisch-Chan HM; Thöny B; Tam YYC; Cullis PR
Nanoscale; 2019 May; 11(18):9023-9031. PubMed ID: 31021343
[TBL] [Abstract][Full Text] [Related]
4. Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function.
Ramezanpour M; Schmidt ML; Bodnariuc I; Kulkarni JA; Leung SSW; Cullis PR; Thewalt JL; Tieleman DP
Nanoscale; 2019 Aug; 11(30):14141-14146. PubMed ID: 31334542
[TBL] [Abstract][Full Text] [Related]
5. Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems.
Leung AK; Tam YY; Chen S; Hafez IM; Cullis PR
J Phys Chem B; 2015 Jul; 119(28):8698-706. PubMed ID: 26087393
[TBL] [Abstract][Full Text] [Related]
6. Molecular-Level Structural Analysis of siRNA-Loaded Lipid Nanoparticles by
Ueda K; Sakagawa Y; Saito T; Fujimoto T; Nakamura M; Sakuma F; Kaneko S; Tokumoto T; Nishimura K; Takeda J; Arai Y; Yamamoto K; Ikeda Y; Higashi K; Moribe K
Mol Pharm; 2023 Sep; 20(9):4729-4742. PubMed ID: 37606988
[No Abstract] [Full Text] [Related]
7. On the role of helper lipids in lipid nanoparticle formulations of siRNA.
Kulkarni JA; Witzigmann D; Leung J; Tam YYC; Cullis PR
Nanoscale; 2019 Nov; 11(45):21733-21739. PubMed ID: 31713568
[TBL] [Abstract][Full Text] [Related]
8. Determination of the interior pH of lipid nanoparticles using a pH-sensitive fluorescent dye-based DNA probe.
Zhao B; Kamanzi A; Zhang Y; Chan KYT; Robertson M; Leslie S; Cullis PR
Biosens Bioelectron; 2024 May; 251():116065. PubMed ID: 38330772
[TBL] [Abstract][Full Text] [Related]
9. Charge-reversible lipid derivative: A novel type of pH-responsive lipid for nanoparticle-mediated siRNA delivery.
Hirai Y; Saeki R; Song F; Koide H; Fukata N; Tomita K; Maeda N; Oku N; Asai T
Int J Pharm; 2020 Jul; 585():119479. PubMed ID: 32473372
[TBL] [Abstract][Full Text] [Related]
10. Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA.
Chen S; Tam YYC; Lin PJC; Sung MMH; Tam YK; Cullis PR
J Control Release; 2016 Aug; 235():236-244. PubMed ID: 27238441
[TBL] [Abstract][Full Text] [Related]
11. Interaction of cholesterol-conjugated ionizable amino lipids with biomembranes: lipid polymorphism, structure-activity relationship, and implications for siRNA delivery.
Zhang J; Fan H; Levorse DA; Crocker LS
Langmuir; 2011 Aug; 27(15):9473-83. PubMed ID: 21648950
[TBL] [Abstract][Full Text] [Related]
12. Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core.
Leung AK; Hafez IM; Baoukina S; Belliveau NM; Zhigaltsev IV; Afshinmanesh E; Tieleman DP; Hansen CL; Hope MJ; Cullis PR
J Phys Chem C Nanomater Interfaces; 2012 Aug; 116(34):18440-18450. PubMed ID: 22962627
[TBL] [Abstract][Full Text] [Related]
13. Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles.
Kulkarni JA; Thomson SB; Zaifman J; Leung J; Wagner PK; Hill A; Tam YYC; Cullis PR; Petkau TL; Leavitt BR
Nanoscale; 2020 Dec; 12(47):23959-23966. PubMed ID: 33241838
[TBL] [Abstract][Full Text] [Related]
14. CHARMM-GUI Membrane Builder for Lipid Nanoparticles with Ionizable Cationic Lipids and PEGylated Lipids.
Park S; Choi YK; Kim S; Lee J; Im W
J Chem Inf Model; 2021 Oct; 61(10):5192-5202. PubMed ID: 34546048
[TBL] [Abstract][Full Text] [Related]
15. Acidic pH-induced changes in lipid nanoparticle membrane packing.
Koitabashi K; Nagumo H; Nakao M; Machida T; Yoshida K; Sakai-Kato K
Biochim Biophys Acta Biomembr; 2021 Aug; 1863(8):183627. PubMed ID: 33901441
[TBL] [Abstract][Full Text] [Related]
16. Structure, activity and uptake mechanism of siRNA-lipid nanoparticles with an asymmetric ionizable lipid.
Suzuki Y; Ishihara H
Int J Pharm; 2016 Aug; 510(1):350-8. PubMed ID: 27374199
[TBL] [Abstract][Full Text] [Related]
17. Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration.
Chen S; Tam YY; Lin PJ; Leung AK; Tam YK; Cullis PR
J Control Release; 2014 Dec; 196():106-12. PubMed ID: 25285610
[TBL] [Abstract][Full Text] [Related]
18. Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to siRNA Delivery.
Kimura N; Maeki M; Sato Y; Ishida A; Tani H; Harashima H; Tokeshi M
ACS Appl Mater Interfaces; 2020 Jul; 12(30):34011-34020. PubMed ID: 32667806
[TBL] [Abstract][Full Text] [Related]
19. pH-labile PEGylation of siRNA-loaded lipid nanoparticle improves active targeting and gene silencing activity in hepatocytes.
Hashiba K; Sato Y; Harashima H
J Control Release; 2017 Sep; 262():239-246. PubMed ID: 28774839
[TBL] [Abstract][Full Text] [Related]
20. Stabilization of Ostwald ripening in low molecular weight amino lipid nanoparticles for systemic delivery of siRNA therapeutics.
Gindy ME; Feuston B; Glass A; Arrington L; Haas RM; Schariter J; Stirdivant SM
Mol Pharm; 2014 Nov; 11(11):4143-53. PubMed ID: 25317715
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
