BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

387 related articles for article (PubMed ID: 29621478)

  • 1. Hyperglycemia-induced Bcl-2/Bax-mediated apoptosis of Schwann cells via mTORC1/S6K1 inhibition in diabetic peripheral neuropathy.
    Zhu L; Hao J; Cheng M; Zhang C; Huo C; Liu Y; Du W; Zhang X
    Exp Cell Res; 2018 Jun; 367(2):186-195. PubMed ID: 29621478
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNMT1, a Novel Regulator Mediating mTORC1/mTORC2 Pathway-Induced NGF Expression in Schwann Cells.
    Cheng M; Lv X; Zhang C; Du W; Liu Y; Zhu L; Hao J
    Neurochem Res; 2018 Nov; 43(11):2141-2154. PubMed ID: 30229399
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TXNIP, a novel key factor to cause Schwann cell dysfunction in diabetic peripheral neuropathy, under the regulation of PI3K/Akt pathway inhibition-induced DNMT1 and DNMT3a overexpression.
    Zhang X; Zhao S; Yuan Q; Zhu L; Li F; Wang H; Kong D; Hao J
    Cell Death Dis; 2021 Jun; 12(7):642. PubMed ID: 34162834
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IFN-γ/mTORC1 decreased Rab11 in Schwann cells of diabetic peripheral neuropathy, inhibiting cell proliferation via GLUT1 downregulation.
    Du W; Zhao S; Gao F; Wei M; An J; Jia K; Li F; Zhu L; Hao J
    J Cell Physiol; 2020 Jul; 235(7-8):5764-5776. PubMed ID: 31970777
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prolonged high-glucose exposure decreased SREBP-1/FASN/ACC in Schwann cells of diabetic mice via blocking PI3K/Akt pathway.
    Zhu L; Du W; Liu Y; Cheng M; Wang X; Zhang C; Lv X; Li F; Zhao S; Hao J
    J Cell Biochem; 2019 Apr; 120(4):5777-5789. PubMed ID: 30362584
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction.
    Ito M; Yurube T; Kakutani K; Maeno K; Takada T; Terashima Y; Kakiuchi Y; Takeoka Y; Miyazaki S; Kuroda R; Nishida K
    Osteoarthritis Cartilage; 2017 Dec; 25(12):2134-2146. PubMed ID: 28888905
    [TBL] [Abstract][Full Text] [Related]  

  • 7. STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
    Du W; Wang N; Li F; Jia K; An J; Liu Y; Wang Y; Zhu L; Zhao S; Hao J
    FASEB J; 2019 Jul; 33(7):8008-8021. PubMed ID: 30913399
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Paeoniflorin protects Schwann cells against high glucose induced oxidative injury by activating Nrf2/ARE pathway and inhibiting apoptosis.
    Yang X; Yao W; Shi H; Liu H; Li Y; Gao Y; Liu R; Xu L
    J Ethnopharmacol; 2016 Jun; 185():361-9. PubMed ID: 26979341
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Autophagy induced by cardamonin is associated with mTORC1 inhibition in SKOV3 cells.
    Shi D; Niu P; Heng X; Chen L; Zhu Y; Zhou J
    Pharmacol Rep; 2018 Oct; 70(5):908-916. PubMed ID: 30099297
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathways.
    Xu C; Liu C; Liu L; Zhang R; Zhang H; Chen S; Luo Y; Chen L; Huang S
    Neuropharmacology; 2015 Oct; 97():35-45. PubMed ID: 26002629
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rapamycin treatment increases hippocampal cell viability in an mTOR-independent manner during exposure to hypoxia mimetic, cobalt chloride.
    Zimmerman MA; Biggers CD; Li PA
    BMC Neurosci; 2018 Dec; 19(1):82. PubMed ID: 30594149
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacological inhibition of S6K1 increases glucose metabolism and Akt signalling in vitro and in diet-induced obese mice.
    Shum M; Bellmann K; St-Pierre P; Marette A
    Diabetologia; 2016 Mar; 59(3):592-603. PubMed ID: 26733005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells.
    Jiang S; Zou Z; Nie P; Wen R; Xiao Y; Tang J
    PLoS One; 2015; 10(7):e0132880. PubMed ID: 26176608
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Akt/mTOR cascade mediates high glucose-induced reductions in BDNF via DNMT1 in Schwann cells in diabetic peripheral neuropathy.
    Zhang CH; Lv X; Du W; Cheng MJ; Liu YP; Zhu L; Hao J
    Exp Cell Res; 2019 Oct; 383(1):111502. PubMed ID: 31323191
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Astragaloside IV alleviates Schwann cell injury in diabetic peripheral neuropathy by regulating microRNA-155-mediated autophagy.
    Yin Y; Qu H; Yang Q; Fang Z; Gao R
    Phytomedicine; 2021 Nov; 92():153749. PubMed ID: 34601220
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors.
    Melick CH; Jewell JL
    Biochem J; 2020 May; 477(10):1847-1863. PubMed ID: 32347294
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting mTORC1/2 with OSI-027 inhibits proliferation and migration of keloid keratinocytes.
    Chen J; Liu K; Liu Y; Wang X; Zhang Z
    Exp Dermatol; 2019 Mar; 28(3):270-275. PubMed ID: 30650200
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuroprotection of resveratrol against cadmium-poisoning acts through dual inhibition of mTORC1/2 signaling.
    Liu C; Zhang R; Yang L; Ji T; Zhu C; Liu B; Zhang H; Xu C; Zhang N; Huang S; Chen L
    Neuropharmacology; 2022 Nov; 219():109236. PubMed ID: 36049535
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes.
    Veilleux A; Houde VP; Bellmann K; Marette A
    Mol Endocrinol; 2010 Apr; 24(4):766-78. PubMed ID: 20203102
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Artesunate Inhibits Apoptosis and Promotes Survival in Schwann Cells via the PI3K/AKT/mTOR Axis in Diabetic Peripheral Neuropathy.
    Zhang X; Liang Z; Zhou Y; Wang F; Wei S; Tan B; Guo Y
    Biol Pharm Bull; 2023; 46(6):764-772. PubMed ID: 37258141
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.