153 related articles for article (PubMed ID: 29622678)
1. Calcium-induced structural rearrangements release autoinhibition in the Rap-GEF CalDAG-GEFI.
Cook AA; Deng W; Ren J; Li R; Sondek J; Bergmeier W
J Biol Chem; 2018 Jun; 293(22):8521-8529. PubMed ID: 29622678
[TBL] [Abstract][Full Text] [Related]
2. Phosphorylation of the guanine-nucleotide-exchange factor CalDAG-GEFI by protein kinase A regulates Ca(2+)-dependent activation of platelet Rap1b GTPase.
Guidetti GF; Manganaro D; Consonni A; Canobbio I; Balduini C; Torti M
Biochem J; 2013 Jul; 453(1):115-23. PubMed ID: 23600630
[TBL] [Abstract][Full Text] [Related]
3. Phosphorylation of CalDAG-GEFI by protein kinase A prevents Rap1b activation.
Subramanian H; Zahedi RP; Sickmann A; Walter U; Gambaryan S
J Thromb Haemost; 2013 Aug; 11(8):1574-82. PubMed ID: 23611601
[TBL] [Abstract][Full Text] [Related]
4. CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation.
Crittenden JR; Bergmeier W; Zhang Y; Piffath CL; Liang Y; Wagner DD; Housman DE; Graybiel AM
Nat Med; 2004 Sep; 10(9):982-6. PubMed ID: 15334074
[TBL] [Abstract][Full Text] [Related]
5. CLL2-1, a chemical derivative of orchid 1,4-phenanthrenequinones, inhibits human platelet aggregation through thiol modification of calcium-diacylglycerol guanine nucleotide exchange factor-I (CalDAG-GEFI).
Liao CY; Lee CL; Wang HC; Liang SS; Kung PH; Wu YC; Chang FR; Wu CC
Free Radic Biol Med; 2015 Jan; 78():101-10. PubMed ID: 25451646
[TBL] [Abstract][Full Text] [Related]
6. Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor.
Clyde-Smith J; Silins G; Gartside M; Grimmond S; Etheridge M; Apolloni A; Hayward N; Hancock JF
J Biol Chem; 2000 Oct; 275(41):32260-7. PubMed ID: 10918068
[TBL] [Abstract][Full Text] [Related]
7. Marked bleeding diathesis in patients with platelet dysfunction due to a novel mutation in RASGRP2, encoding CalDAG-GEFI (p.Gly305Asp).
Bermejo E; Alberto MF; Paul DS; Cook AA; Nurden P; Sanchez Luceros A; Nurden AT; Bergmeier W
Platelets; 2018 Jan; 29(1):84-86. PubMed ID: 28726538
[TBL] [Abstract][Full Text] [Related]
8. CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin alphaIIbbeta3 in platelets.
Cifuni SM; Wagner DD; Bergmeier W
Blood; 2008 Sep; 112(5):1696-703. PubMed ID: 18544684
[TBL] [Abstract][Full Text] [Related]
9. Identification of CalDAG-GEFI as an intracellular target for the vicinal dithiol binding agent phenylarsine oxide in human platelets.
Kuo CY; Wang HC; Kung PH; Lu CY; Liao CY; Wu MT; Wu CC
Thromb Haemost; 2014 May; 111(5):892-901. PubMed ID: 24352565
[TBL] [Abstract][Full Text] [Related]
10. CalDAG-GEFI is at the nexus of calcium-dependent platelet activation.
Stefanini L; Roden RC; Bergmeier W
Blood; 2009 Sep; 114(12):2506-14. PubMed ID: 19628710
[TBL] [Abstract][Full Text] [Related]
11. Calcium-diacylglycerol guanine nucleotide exchange factor I gene mutations associated with loss of function in canine platelets.
Boudreaux MK; Catalfamo JL; Klok M
Transl Res; 2007 Aug; 150(2):81-92. PubMed ID: 17656327
[TBL] [Abstract][Full Text] [Related]
12. The CalDAG-GEFI/Rap1/αIIbβ3 axis minimally contributes to accelerated platelet clearance in mice with constitutive store-operated calcium entry.
Lee RH; Rocco DJ; Nieswandt B; Bergmeier W
Platelets; 2023 Dec; 34(1):2157383. PubMed ID: 36683325
[TBL] [Abstract][Full Text] [Related]
13. Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction.
Lozano ML; Cook A; Bastida JM; Paul DS; Iruin G; Cid AR; Adan-Pedroso R; Ramón González-Porras J; Hernández-Rivas JM; Fletcher SJ; Johnson B; Morgan N; Ferrer-Marin F; Vicente V; Sondek J; Watson SP; Bergmeier W; Rivera J
Blood; 2016 Sep; 128(9):1282-9. PubMed ID: 27235135
[TBL] [Abstract][Full Text] [Related]
14. Relative contributions of stromal interaction molecule 1 and CalDAG-GEFI to calcium-dependent platelet activation and thrombosis.
Ahmad F; Boulaftali Y; Greene TK; Ouellette TD; Poncz M; Feske S; Bergmeier W
J Thromb Haemost; 2011 Oct; 9(10):2077-86. PubMed ID: 21848641
[TBL] [Abstract][Full Text] [Related]
15. CalDAG-GEFI Deficiency in a Family with Symptomatic Heterozygous and Homozygous Carriers of a Likely Pathogenic Variant in
Morais S; Pereira M; Lau C; Gonçalves A; Monteiro C; Gonçalves M; Oliveira J; Moreira L; Cruz E; Santos R; Lima M
Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830306
[No Abstract] [Full Text] [Related]
16. A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2.
Guo FF; Kumahara E; Saffen D
J Biol Chem; 2001 Jul; 276(27):25568-81. PubMed ID: 11292831
[TBL] [Abstract][Full Text] [Related]
17. Human CalDAG-GEFI deficiency increases bleeding and delays αIIbβ3 activation.
Kato H; Nakazawa Y; Kurokawa Y; Kashiwagi H; Morikawa Y; Morita D; Banno F; Honda S; Kanakura Y; Tomiyama Y
Blood; 2016 Dec; 128(23):2729-2733. PubMed ID: 27663674
[TBL] [Abstract][Full Text] [Related]
18. CalDAG-GEFI and platelet activation.
Stefanini L; Bergmeier W
Platelets; 2010; 21(4):239-43. PubMed ID: 20218908
[TBL] [Abstract][Full Text] [Related]
19. Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.
Bergmeier W; Goerge T; Wang HW; Crittenden JR; Baldwin AC; Cifuni SM; Housman DE; Graybiel AM; Wagner DD
J Clin Invest; 2007 Jun; 117(6):1699-707. PubMed ID: 17492052
[TBL] [Abstract][Full Text] [Related]
20. Human CalDAG-GEFI gene (RASGRP2) mutation affects platelet function and causes severe bleeding.
Canault M; Ghalloussi D; Grosdidier C; Guinier M; Perret C; Chelghoum N; Germain M; Raslova H; Peiretti F; Morange PE; Saut N; Pillois X; Nurden AT; Cambien F; Pierres A; van den Berg TK; Kuijpers TW; Alessi MC; Tregouet DA
J Exp Med; 2014 Jun; 211(7):1349-62. PubMed ID: 24958846
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
