These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 29632192)

  • 1. Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
    Hu H; Nemecz Á; Van Renterghem C; Fourati Z; Sauguet L; Corringer PJ; Delarue M
    Proc Natl Acad Sci U S A; 2018 Apr; 115(17):E3959-E3968. PubMed ID: 29632192
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel.
    Hu H; Howard RJ; Bastolla U; Lindahl E; Delarue M
    Proc Natl Acad Sci U S A; 2020 Jun; 117(24):13437-13446. PubMed ID: 32482881
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of the prokaryotic pentameric ligand-gated ion channel ELIC by divalent cations.
    Zimmermann I; Marabelli A; Bertozzi C; Sivilotti LG; Dutzler R
    PLoS Biol; 2012; 10(11):e1001429. PubMed ID: 23185134
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.
    Chen Q; Wells MM; Tillman TS; Kinde MN; Cohen A; Xu Y; Tang P
    Structure; 2017 Jan; 25(1):180-187. PubMed ID: 27916519
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel.
    Hilf RJ; Dutzler R
    Nature; 2009 Jan; 457(7225):115-8. PubMed ID: 18987630
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).
    Spurny R; Billen B; Howard RJ; Brams M; Debaveye S; Price KL; Weston DA; Strelkov SV; Tytgat J; Bertrand S; Bertrand D; Lummis SCR; Ulens C
    J Biol Chem; 2013 Mar; 288(12):8355-8364. PubMed ID: 23364792
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Macroscopic kinetics of pentameric ligand gated ion channels: comparisons between two prokaryotic channels and one eukaryotic channel.
    Laha KT; Ghosh B; Czajkowski C
    PLoS One; 2013; 8(11):e80322. PubMed ID: 24260369
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine.
    Pan J; Chen Q; Willenbring D; Yoshida K; Tillman T; Kashlan OB; Cohen A; Kong XP; Xu Y; Tang P
    Nat Commun; 2012 Mar; 3():714. PubMed ID: 22395605
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystallographic studies of pharmacological sites in pentameric ligand-gated ion channels.
    Sauguet L; Shahsavar A; Delarue M
    Biochim Biophys Acta; 2015 Mar; 1850(3):511-23. PubMed ID: 24836522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The prokaryote ligand-gated ion channel ELIC captured in a pore blocker-bound conformation by the Alzheimer's disease drug memantine.
    Ulens C; Spurny R; Thompson AJ; Alqazzaz M; Debaveye S; Han L; Price K; Villalgordo JM; Tresadern G; Lynch JW; Lummis SC
    Structure; 2014 Oct; 22(10):1399-407. PubMed ID: 25199693
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Site-directed spin labeling reveals pentameric ligand-gated ion channel gating motions.
    Dellisanti CD; Ghosh B; Hanson SM; Raspanti JM; Grant VA; Diarra GM; Schuh AM; Satyshur K; Klug CS; Czajkowski C
    PLoS Biol; 2013 Nov; 11(11):e1001714. PubMed ID: 24260024
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A chimeric prokaryotic pentameric ligand-gated channel reveals distinct pathways of activation.
    Schmandt N; Velisetty P; Chalamalasetti SV; Stein RA; Bonner R; Talley L; Parker MD; Mchaourab HS; Yee VC; Lodowski DT; Chakrapani S
    J Gen Physiol; 2015 Oct; 146(4):323-40. PubMed ID: 26415570
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.
    Sauguet L; Shahsavar A; Poitevin F; Huon C; Menny A; Nemecz À; Haouz A; Changeux JP; Corringer PJ; Delarue M
    Proc Natl Acad Sci U S A; 2014 Jan; 111(3):966-71. PubMed ID: 24367074
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A gating mechanism of pentameric ligand-gated ion channels.
    Calimet N; Simoes M; Changeux JP; Karplus M; Taly A; Cecchini M
    Proc Natl Acad Sci U S A; 2013 Oct; 110(42):E3987-96. PubMed ID: 24043807
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel.
    Hilf RJ; Bertozzi C; Zimmermann I; Reiter A; Trauner D; Dutzler R
    Nat Struct Mol Biol; 2010 Nov; 17(11):1330-6. PubMed ID: 21037567
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC.
    Chen Q; Kinde MN; Arjunan P; Wells MM; Cohen AE; Xu Y; Tang P
    Sci Rep; 2015 Sep; 5():13833. PubMed ID: 26346220
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Common Anesthetic-binding Site for Inhibition of Pentameric Ligand-gated Ion Channels.
    Kinde MN; Bu W; Chen Q; Xu Y; Eckenhoff RG; Tang P
    Anesthesiology; 2016 Mar; 124(3):664-73. PubMed ID: 26756520
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site.
    Sridhar A; Lummis SCR; Pasini D; Mehregan A; Brams M; Kambara K; Bertrand D; Lindahl E; Howard RJ; Ulens C
    J Biol Chem; 2021 Aug; 297(2):100899. PubMed ID: 34157288
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intramembrane aromatic interactions influence the lipid sensitivities of pentameric ligand-gated ion channels.
    Carswell CL; Sun J; Baenziger JE
    J Biol Chem; 2015 Jan; 290(4):2496-507. PubMed ID: 25519904
    [TBL] [Abstract][Full Text] [Related]  

  • 20. From hopanoids to cholesterol: Molecular clocks of pentameric ligand-gated ion channels.
    Barrantes FJ; Fantini J
    Prog Lipid Res; 2016 Jul; 63():1-13. PubMed ID: 27084463
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.