BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 29634991)

  • 1. Integrating in vitro and in silico approaches to evaluate the "dual functionality" of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils.
    Haj E; Losev Y; Guru KrishnaKumar V; Pichinuk E; Engel H; Raveh A; Gazit E; Segal D
    Biochim Biophys Acta Gen Subj; 2018 Jul; 1862(7):1565-1575. PubMed ID: 29634991
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanistic insights into remodeled Tau-derived PHF6 peptide fibrils by Naphthoquinone-Tryptophan hybrids.
    KrishnaKumar VG; Paul A; Gazit E; Segal D
    Sci Rep; 2018 Jan; 8(1):71. PubMed ID: 29311706
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer's disease-like symptoms in animal model.
    Viswanathan GK; Shwartz D; Losev Y; Arad E; Shemesh C; Pichinuk E; Engel H; Raveh A; Jelinek R; Cooper I; Gosselet F; Gazit E; Segal D
    Cell Mol Life Sci; 2020 Jul; 77(14):2795-2813. PubMed ID: 31562564
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of tau amyloid formation and disruption of its preformed fibrils by Naphthoquinone-Dopamine hybrid.
    Paul A; Viswanathan GK; Huber A; Arad E; Engel H; Jelinek R; Gazit E; Segal D
    FEBS J; 2021 Jul; 288(14):4267-4290. PubMed ID: 33523571
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selection of a d-Enantiomeric Peptide Specifically Binding to PHF6 for Inhibiting Tau Aggregation in Transgenic Mice.
    Zhang X; Zhang X; Zhong M; Zhao P; Guo C; Li Y; Wang T; Gao H
    ACS Chem Neurosci; 2020 Dec; 11(24):4240-4253. PubMed ID: 33284003
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of the Aggregation and Toxicity of the Minimal Amyloidogenic Fragment of Tau by Its Pro-Substituted Analogues.
    Chemerovski-Glikman M; Frenkel-Pinter M; Mdah R; Abu-Mokh A; Gazit E; Segal D
    Chemistry; 2017 Jul; 23(40):9618-9624. PubMed ID: 28544138
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disclosing the Mechanism of Spontaneous Aggregation and Template-Induced Misfolding of the Key Hexapeptide (PHF6) of Tau Protein Based on Molecular Dynamics Simulation.
    Liu H; Zhong H; Liu X; Zhou S; Tan S; Liu H; Yao X
    ACS Chem Neurosci; 2019 Dec; 10(12):4810-4823. PubMed ID: 31661961
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Primary Fibril Nucleation of Aggregation Prone Tau Fragments PHF6 and PHF6.
    Smit FX; Luiken JA; Bolhuis PG
    J Phys Chem B; 2017 Apr; 121(15):3250-3261. PubMed ID: 27776213
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural insights into the co-aggregation of Aβ and tau amyloid core peptides: Revealing potential pathological heterooligomers by simulations.
    Li X; Chen Y; Yang Z; Zhang S; Wei G; Zhang L
    Int J Biol Macromol; 2024 Jan; 254(Pt 2):127841. PubMed ID: 37924907
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent Tau Aggregation Inhibitor D-Peptides Selected against Tau-Repeat 2 Using Mirror Image Phage Display.
    Malhis M; Kaniyappan S; Aillaud I; Chandupatla RR; Ramirez LM; Zweckstetter M; Horn AHC; Mandelkow E; Sticht H; Funke SA
    Chembiochem; 2021 Nov; 22(21):3049-3059. PubMed ID: 34375027
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carbamylation promotes amyloidogenesis and induces structural changes in Tau-core hexapeptide fibrils.
    Guru KrishnaKumar V; Baweja L; Ralhan K; Gupta S
    Biochim Biophys Acta Gen Subj; 2018 Dec; 1862(12):2590-2604. PubMed ID: 30071272
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Terminal Capping of an Amyloidogenic Tau Fragment Modulates Its Fibrillation Propensity.
    Arya S; Ganguly P; Arsiccio A; Claud SL; Trapp B; Schonfeld GE; Liu X; Lazar Cantrell K; Shea JE; Bowers MT
    J Phys Chem B; 2020 Oct; 124(40):8772-8783. PubMed ID: 32816481
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of All-Atom Molecular Mechanics Force Fields on Amyloid Peptide Assembly: The Case of PHF6 Peptide of Tau Protein.
    Man VH; He X; Gao J; Wang J
    J Chem Theory Comput; 2021 Oct; 17(10):6458-6471. PubMed ID: 34491058
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antagonistic Activity of Naphthoquinone-Based Hybrids toward Amyloids Associated with Alzheimer's Disease and Type-2 Diabetes.
    Paul A; Viswanathan GK; Mahapatra S; Balboni G; Pacifico S; Gazit E; Segal D
    ACS Chem Neurosci; 2019 Aug; 10(8):3510-3520. PubMed ID: 31282646
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Atomistic Insights into the Inhibitory Mechanism of Tyrosine Phosphorylation against the Aggregation of Human Tau Fragment PHF6.
    Zou Y; Guan L; Tan J; Qi B; Wang Y; Zhang Q; Sun Y
    J Phys Chem B; 2023 Jan; 127(1):335-345. PubMed ID: 36594671
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Baicalein inhibits heparin-induced Tau aggregation by initializing non-toxic Tau oligomer formation.
    Sonawane SK; Uversky VN; Chinnathambi S
    Cell Commun Signal; 2021 Feb; 19(1):16. PubMed ID: 33579328
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hsp90 directly interacts, in vitro, with amyloid structures and modulates their assembly and disassembly.
    Schirmer C; Lepvrier E; Duchesne L; Decaux O; Thomas D; Delamarche C; Garnier C
    Biochim Biophys Acta; 2016 Nov; 1860(11 Pt A):2598-2609. PubMed ID: 27495389
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deciphering the Inhibitory Mechanism of Naphthoquinone-Dopamine on the Aggregation of Tau Core Fragments PHF6* and PHF6.
    Zou Y; Qi B; Tan J; Guan L; Zhang Q; Sun Y; Huang F
    ACS Chem Neurosci; 2023 Sep; 14(17):3265-3277. PubMed ID: 37585669
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mirror-Image Phage Display for the Selection of D-Amino Acid Peptide Ligands as Potential Therapeutics.
    Malhis M; Funke SA
    Curr Protoc; 2024 Feb; 4(2):e957. PubMed ID: 38372457
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based inhibitors of tau aggregation.
    Seidler PM; Boyer DR; Rodriguez JA; Sawaya MR; Cascio D; Murray K; Gonen T; Eisenberg DS
    Nat Chem; 2018 Feb; 10(2):170-176. PubMed ID: 29359764
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.