BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

290 related articles for article (PubMed ID: 29635516)

  • 1. Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex.
    McKenna J; Kapfhamer D; Kinchen JM; Wasek B; Dunworth M; Murray-Stewart T; Bottiglieri T; Casero RA; Gambello MJ
    Hum Mol Genet; 2018 Jun; 27(12):2113-2124. PubMed ID: 29635516
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ornithine decarboxylase, the rate-limiting enzyme of polyamine synthesis, modifies brain pathology in a mouse model of tuberous sclerosis complex.
    Kapfhamer D; McKenna J; Yoon CJ; Murray-Stewart T; Casero RA; Gambello MJ
    Hum Mol Genet; 2020 Aug; 29(14):2395-2407. PubMed ID: 32588887
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Upregulation of 6-phosphofructo-2-kinase (PFKFB3) by hyperactivated mammalian target of rapamycin complex 1 is critical for tumor growth in tuberous sclerosis complex.
    Wang Y; Tang S; Wu Y; Wan X; Zhou M; Li H; Zha X
    IUBMB Life; 2020 May; 72(5):965-977. PubMed ID: 31958214
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis.
    Frau M; Feo F; Pascale RM
    J Hepatol; 2013 Oct; 59(4):830-41. PubMed ID: 23665184
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse.
    Way SW; McKenna J; Mietzsch U; Reith RM; Wu HC; Gambello MJ
    Hum Mol Genet; 2009 Apr; 18(7):1252-65. PubMed ID: 19150975
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Abnormal glycogen storage in tuberous sclerosis complex caused by impairment of mTORC1-dependent and -independent signaling pathways.
    Pal R; Xiong Y; Sardiello M
    Proc Natl Acad Sci U S A; 2019 Feb; 116(8):2977-2986. PubMed ID: 30728291
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Decreased rates of cerebral protein synthesis measured in vivo in a mouse model of Tuberous Sclerosis Complex: unexpected consequences of reduced tuberin.
    Saré RM; Huang T; Burlin T; Loutaev I; Smith CB
    J Neurochem; 2018 Jun; 145(5):417-425. PubMed ID: 29364507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The specificity and role of microglia in epileptogenesis in mouse models of tuberous sclerosis complex.
    Zhang B; Zou J; Han L; Beeler B; Friedman JL; Griffin E; Piao YS; Rensing NR; Wong M
    Epilepsia; 2018 Sep; 59(9):1796-1806. PubMed ID: 30079598
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutational analysis of TSC1 and TSC2 genes in Tuberous Sclerosis Complex patients from Greece.
    Avgeris S; Fostira F; Vagena A; Ninios Y; Delimitsou A; Vodicka R; Vrtel R; Youroukos S; Stravopodis DJ; Vlassi M; Astrinidis A; Yannoukakos D; Voutsinas GE
    Sci Rep; 2017 Dec; 7(1):16697. PubMed ID: 29196670
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Revisiting Brain Tuberous Sclerosis Complex in Rat and Human: Shared Molecular and Cellular Pathology Leads to Distinct Neurophysiological and Behavioral Phenotypes.
    Kútna V; O'Leary VB; Newman E; Hoschl C; Ovsepian SV
    Neurotherapeutics; 2021 Apr; 18(2):845-858. PubMed ID: 33398801
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer.
    Mrozek EM; Bajaj V; Guo Y; Malinowska IA; Zhang J; Kwiatkowski DJ
    PLoS One; 2021; 16(4):e0248380. PubMed ID: 33891611
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Finding a cure for tuberous sclerosis complex: From genetics through to targeted drug therapies.
    McEneaney LJ; Tee AR
    Adv Genet; 2019; 103():91-118. PubMed ID: 30904097
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Renal disease in tuberous sclerosis complex: pathogenesis and therapy.
    Lam HC; Siroky BJ; Henske EP
    Nat Rev Nephrol; 2018 Nov; 14(11):704-716. PubMed ID: 30232410
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Therapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shift.
    Medvetz D; Priolo C; Henske EP
    Mol Cancer Res; 2015 Jan; 13(1):3-8. PubMed ID: 25298408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β.
    Ogórek B; Lam HC; Khabibullin D; Liu HJ; Nijmeh J; Triboulet R; Kwiatkowski DJ; Gregory RI; Henske EP
    Hum Mol Genet; 2018 May; 27(9):1654-1663. PubMed ID: 29509898
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutational analysis of TSC1 and TSC2 in Danish patients with tuberous sclerosis complex.
    Rosengren T; Nanhoe S; de Almeida LGD; Schönewolf-Greulich B; Larsen LJ; Hey CAB; Dunø M; Ek J; Risom L; Nellist M; Møller LB
    Sci Rep; 2020 Jun; 10(1):9909. PubMed ID: 32555378
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Tuberous Sclerosis Complex].
    Kaneda M
    Brain Nerve; 2019 Apr; 71(4):374-379. PubMed ID: 30988224
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment.
    Mills JD; Iyer AM; van Scheppingen J; Bongaarts A; Anink JJ; Janssen B; Zimmer TS; Spliet WG; van Rijen PC; Jansen FE; Feucht M; Hainfellner JA; Krsek P; Zamecnik J; Kotulska K; Jozwiak S; Jansen A; Lagae L; Curatolo P; Kwiatkowski DJ; Pasterkamp RJ; Senthilkumar K; von Oerthel L; Hoekman MF; Gorter JA; Crino PB; Mühlebner A; Scicluna BP; Aronica E
    Sci Rep; 2017 Aug; 7(1):8089. PubMed ID: 28808237
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex.
    Terry BK; Park R; Cho SH; Crino PB; Kim S
    Hum Mol Genet; 2022 Jun; 31(12):1979-1996. PubMed ID: 34999833
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genetic Etiologies, Diagnosis, and Treatment of Tuberous Sclerosis Complex.
    Salussolia CL; Klonowska K; Kwiatkowski DJ; Sahin M
    Annu Rev Genomics Hum Genet; 2019 Aug; 20():217-240. PubMed ID: 31018109
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.