BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 29641495)

  • 1. Furan- and Thiophene-2-Carbonyl Amino Acid Derivatives Activate Hypoxia-Inducible Factor via Inhibition of Factor Inhibiting Hypoxia-Inducible Factor-1.
    Kawaguchi SI; Gonda Y; Yamamoto T; Sato Y; Shinohara H; Kobiki Y; Ichimura A; Dan T; Sonoda M; Miyata T; Ogawa A; Tsujita T
    Molecules; 2018 Apr; 23(4):. PubMed ID: 29641495
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway.
    Chen DY; Fabrizio JA; Wilkins SE; Dave KA; Gorman JJ; Gleadle JM; Fleming SB; Peet DJ; Mercer AA
    J Virol; 2017 Jan; 91(1):. PubMed ID: 27795413
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of the Oxygen-Sensing Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-Inducible Factor: A Potential Hypoxia Response Modulating Strategy.
    Wu Y; Li Z; McDonough MA; Schofield CJ; Zhang X
    J Med Chem; 2021 Jun; 64(11):7189-7209. PubMed ID: 34029087
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
    Dayan F; Roux D; Brahimi-Horn MC; Pouyssegur J; Mazure NM
    Cancer Res; 2006 Apr; 66(7):3688-98. PubMed ID: 16585195
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha.
    Shin DH; Li SH; Yang SW; Lee BL; Lee MK; Park JW
    FEBS J; 2009 Jul; 276(13):3470-80. PubMed ID: 19456861
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH).
    Flagg SC; Martin CB; Taabazuing CY; Holmes BE; Knapp MJ
    J Inorg Biochem; 2012 Aug; 113():25-30. PubMed ID: 22687491
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity.
    Masson N; Singleton RS; Sekirnik R; Trudgian DC; Ambrose LJ; Miranda MX; Tian YM; Kessler BM; Schofield CJ; Ratcliffe PJ
    EMBO Rep; 2012 Mar; 13(3):251-7. PubMed ID: 22310300
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
    Hewitson KS; McNeill LA; Riordan MV; Tian YM; Bullock AN; Welford RW; Elkins JM; Oldham NJ; Bhattacharya S; Gleadle JM; Ratcliffe PJ; Pugh CW; Schofield CJ
    J Biol Chem; 2002 Jul; 277(29):26351-5. PubMed ID: 12042299
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH).
    Webb JD; Murányi A; Pugh CW; Ratcliffe PJ; Coleman ML
    Biochem J; 2009 May; 420(2):327-33. PubMed ID: 19245366
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deletion of the
    Cai X; Zhang D; Wang J; Liu X; Ouyang G; Xiao W
    J Biol Chem; 2018 Oct; 293(40):15370-15380. PubMed ID: 30126845
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nutlin-3, an Hdm2 antagonist, inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated inactivation of HIF-1alpha.
    Lee YM; Lim JH; Chun YS; Moon HE; Lee MK; Huang LE; Park JW
    Carcinogenesis; 2009 Oct; 30(10):1768-75. PubMed ID: 19696166
    [TBL] [Abstract][Full Text] [Related]  

  • 12. β-N-oxalyl-L-α, β- diaminopropionic acid induces HRE expression by inhibiting HIF-prolyl hydroxylase-2 in normoxic conditions.
    Eslavath RK; Sharma D; Bin Omar NAM; Chikati R; Teli MK; Rajanikant GK; Singh SS
    Eur J Pharmacol; 2016 Nov; 791():405-411. PubMed ID: 27393459
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.
    Dann CE; Bruick RK; Deisenhofer J
    Proc Natl Acad Sci U S A; 2002 Nov; 99(24):15351-6. PubMed ID: 12432100
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity.
    Lancaster DE; McNeill LA; McDonough MA; Aplin RT; Hewitson KS; Pugh CW; Ratcliffe PJ; Schofield CJ
    Biochem J; 2004 Nov; 383(Pt. 3):429-37. PubMed ID: 15239670
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2).
    Janke K; Brockmeier U; Kuhlmann K; Eisenacher M; Nolde J; Meyer HE; Mairbäurl H; Metzen E
    J Cell Sci; 2013 Jun; 126(Pt 12):2629-40. PubMed ID: 23606740
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Featured Article: Hypoxia-inducible factor-1α dependent nuclear entry of factor inhibiting HIF-1.
    Liang K; Ding XQ; Lin C; Kang YJ
    Exp Biol Med (Maywood); 2015 Nov; 240(11):1446-51. PubMed ID: 25687434
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of factor inhibiting HIF (FIH-1) in inhibiting HIF-1 transcriptional activity in glioblastoma multiforme.
    Wang E; Zhang C; Polavaram N; Liu F; Wu G; Schroeder MA; Lau JS; Mukhopadhyay D; Jiang SW; O'Neill BP; Datta K; Li J
    PLoS One; 2014; 9(1):e86102. PubMed ID: 24465898
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of ankyrin repeat-containing proteins as substrates of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible transcription factor.
    Linke S; Hampton-Smith RJ; Peet DJ
    Methods Enzymol; 2007; 435():61-85. PubMed ID: 17998049
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor.
    Lando D; Peet DJ; Gorman JJ; Whelan DA; Whitelaw ML; Bruick RK
    Genes Dev; 2002 Jun; 16(12):1466-71. PubMed ID: 12080085
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.
    Karttunen S; Duffield M; Scrimgeour NR; Squires L; Lim WL; Dallas ML; Scragg JL; Chicher J; Dave KA; Whitelaw ML; Peers C; Gorman JJ; Gleadle JM; Rychkov GY; Peet DJ
    J Cell Sci; 2015 Jan; 128(2):225-31. PubMed ID: 25413349
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.