BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 29643386)

  • 1. Somatic activating mutations in MAP2K1 cause melorheostosis.
    Kang H; Jha S; Deng Z; Fratzl-Zelman N; Cabral WA; Ivovic A; Meylan F; Hanson EP; Lange E; Katz J; Roschger P; Klaushofer K; Cowen EW; Siegel RM; Marini JC; Bhattacharyya T
    Nat Commun; 2018 Apr; 9(1):1390. PubMed ID: 29643386
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway.
    Kang H; Jha S; Ivovic A; Fratzl-Zelman N; Deng Z; Mitra A; Cabral WA; Hanson EP; Lange E; Cowen EW; Katz J; Roschger P; Klaushofer K; Dale RK; Siegel RM; Bhattacharyya T; Marini JC
    J Exp Med; 2020 May; 217(5):. PubMed ID: 32232430
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Distinct Clinical and Pathological Features of Melorheostosis Associated With Somatic MAP2K1 Mutations.
    Jha S; Fratzl-Zelman N; Roschger P; Papadakis GZ; Cowen EW; Kang H; Lehky TJ; Alter K; Deng Z; Ivovic A; Flynn L; Reynolds JC; Dasgupta A; Miettinen M; Lange E; Katz J; Klaushofer K; Marini JC; Siegel RM; Bhattacharyya T
    J Bone Miner Res; 2019 Jan; 34(1):145-156. PubMed ID: 30138550
    [TBL] [Abstract][Full Text] [Related]  

  • 4. VEGF Secretion Drives Bone Formation in Classical MAP2K1+ Melorheostosis.
    Allbritton-King JD; Maity J; Patel A; Colbert RA; Navid F; Bhattacharyya T
    J Bone Miner Res; 2023 Dec; 38(12):1834-1845. PubMed ID: 37737377
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A multi-omics approach expands the mutational spectrum of MAP2K1-related melorheostosis.
    De Ridder R; Boudin E; Zillikens MC; Ibrahim J; van der Eerden BCJ; Van Hul W; Mortier G
    Bone; 2020 Aug; 137():115406. PubMed ID: 32387835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distribution and Functional Consequences of Somatic MAP2K1 Variants in Affected Skin Associated with Bone Lesions in Melorheostosis.
    Jha S; Ivovic A; Kang H; Meylan F; Hanson EP; Rimland C; Lange E; Katz J; McBride A; Warner AC; Edmondson EF; Cowen EW; Marini JC; Siegel RM; Bhattacharyya T
    J Invest Dermatol; 2021 Mar; 141(3):688-692.e11. PubMed ID: 32791068
    [No Abstract]   [Full Text] [Related]  

  • 7. Melorheostotic Bone Lesions Caused by Somatic Mutations in MAP2K1 Have Deteriorated Microarchitecture and Periosteal Reaction.
    Fratzl-Zelman N; Roschger P; Kang H; Jha S; Roschger A; Blouin S; Deng Z; Cabral WA; Ivovic A; Katz J; Siegel RM; Klaushofer K; Fratzl P; Bhattacharyya T; Marini JC
    J Bone Miner Res; 2019 May; 34(5):883-895. PubMed ID: 30667555
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clinical characteristics of 10 Chinese patients with melorheostosis and identification of a somatic MAP2K1 variant in one case.
    Han X; Xu Y; Wei Z; Wang C; Yue H; Zhang Z
    Mol Genet Genomic Med; 2022 Oct; 10(10):e2043. PubMed ID: 36004822
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A TGF-beta-inducible cell adhesion molecule, betaig-h3, is downregulated in melorheostosis and involved in osteogenesis.
    Kim JE; Kim EH; Han EH; Park RW; Park IH; Jun SH; Kim JC; Young MF; Kim IS
    J Cell Biochem; 2000 Mar; 77(2):169-78. PubMed ID: 10723084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Melorheostosis and Osteopoikilosis: A Review of Clinical Features and Pathogenesis.
    Wordsworth P; Chan M
    Calcif Tissue Int; 2019 May; 104(5):530-543. PubMed ID: 30989250
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Constitutive activation of MEK1 in osteoprogenitors increases strength of bone despite impairing mineralization.
    Fowlkes JL; Bunn RC; Ray PD; Kalaitzoglou E; Uppuganti S; Unal M; Nyman JS; Thrailkill KM
    Bone; 2020 Jan; 130():115106. PubMed ID: 31689526
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Melorheostosis and Osteopoikilosis Clinical and Molecular Description of an Italian Case Series.
    Gnoli M; Staals EL; Campanacci L; Bedeschi MF; Faletra F; Gallone S; Gaudio A; Mattina T; Gurrieri F; Percesepe A; Neri I; Virdi A; Tremosini M; Milanesi A; Brizola E; Pedrini E; Sangiorgi L
    Calcif Tissue Int; 2019 Aug; 105(2):215-221. PubMed ID: 31129707
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CT analysis of anatomical distribution of melorheostosis challenges the sclerotome hypothesis.
    Jha S; Laucis N; Kim L; Malayeri A; Dasgupta A; Papadakis GZ; Karantanas A; Torres M; Bhattacharyya T
    Bone; 2018 Dec; 117():31-36. PubMed ID: 30218789
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fibroblast growth factor receptor 2 promotes osteogenic differentiation in mesenchymal cells via ERK1/2 and protein kinase C signaling.
    Miraoui H; Oudina K; Petite H; Tanimoto Y; Moriyama K; Marie PJ
    J Biol Chem; 2009 Feb; 284(8):4897-904. PubMed ID: 19117954
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Altered chondrocyte differentiation, matrix mineralization and MEK-Erk1/2 signaling in an INPPL1 catalytic knock-out mouse model of opsismodysplasia.
    Vande Catsyne CA; Sayyed SA; Molina-Ortiz P; Moes B; Communi D; Muller J; Heusschen R; Caers J; Azzi A; Erneux C; Schurmans S
    Adv Biol Regul; 2020 May; 76():100651. PubMed ID: 31519471
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histopathological characterization of melorheostosis.
    Hoshi K; Amizuka N; Kurokawa T; Nakamura K; Shiro R; Ozawa H
    Orthopedics; 2001 Mar; 24(3):273-7. PubMed ID: 11300293
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Osteoblast Dysfunction in Non-Hereditary Sclerosing Bone Diseases.
    Giardullo L; Altomare A; Rotondo C; Corrado A; Cantatore FP
    Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360745
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel therapeutic approach with Caviunin-based isoflavonoid that en routes bone marrow cells to bone formation via BMP2/Wnt-β-catenin signaling.
    Kushwaha P; Khedgikar V; Gautam J; Dixit P; Chillara R; Verma A; Thakur R; Mishra DP; Singh D; Maurya R; Chattopadhyay N; Mishra PR; Trivedi R
    Cell Death Dis; 2014 Sep; 5(9):e1422. PubMed ID: 25232676
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Melorheostosis: Exome sequencing of an associated dermatosis implicates postzygotic mosaicism of mutated KRAS.
    Whyte MP; Griffith M; Trani L; Mumm S; Gottesman GS; McAlister WH; Krysiak K; Lesurf R; Skidmore ZL; Campbell KM; Rosman IS; Bayliss S; Bijanki VN; Nenninger A; Van Tine BA; Griffith OL; Mardis ER
    Bone; 2017 Aug; 101():145-155. PubMed ID: 28434888
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations of
    Schmidt J; Ramis-Zaldivar JE; Nadeu F; Gonzalez-Farre B; Navarro A; Egan C; Montes-Mojarro IA; Marafioti T; Cabeçadas J; van der Walt J; Dojcinov S; Rosenwald A; Ott G; Bonzheim I; Fend F; Campo E; Jaffe ES; Salaverria I; Quintanilla-Martinez L
    Blood; 2017 Jul; 130(3):323-327. PubMed ID: 28533310
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.