BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

358 related articles for article (PubMed ID: 2964897)

  • 1. Formation of conjugates of 2-fluoro-beta-alanine and bile acids during the metabolism of 5-fluorouracil and 5-fluoro-2-deoxyuridine in the isolated perfused rat liver.
    Sweeny DJ; Barnes S; Diasio RB
    Cancer Res; 1988 Apr; 48(8):2010-4. PubMed ID: 2964897
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 19F NMR spectrometry evidence for bile acid conjugates of alpha-fluoro-beta-alanine as the main biliary metabolites of antineoplastic fluoropyrimidines in humans.
    Malet-Martino MC; Bernadou J; Martino R; Armand JP
    Drug Metab Dispos; 1988; 16(1):78-84. PubMed ID: 2894959
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolism of 5-fluorouracil to an N-cholyl-2-fluoro-beta-alanine conjugate: previously unrecognized role for bile acids in drug conjugation.
    Sweeny DJ; Barnes S; Heggie GD; Diasio RB
    Proc Natl Acad Sci U S A; 1987 Aug; 84(15):5439-43. PubMed ID: 3110788
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Fluoro-beta-alanine, a previously unrecognized substrate for bile acid coenzyme A:amino acid:N-acyltransferase from human liver.
    Johnson MR; Barnes S; Sweeny DJ; Diasio RB
    Biochem Pharmacol; 1990 Sep; 40(6):1241-6. PubMed ID: 2119585
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disposition and metabolism of 2-fluoro-beta-alanine conjugates of bile acids following secretion into bile.
    Zhang RW; Barnes S; Diasio RB
    Biochim Biophys Acta; 1991 Apr; 1096(3):179-86. PubMed ID: 1902118
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nonlinear elimination kinetics of 5-fluoro-2'-deoxyuridine in isolated perfused rat liver and isolated hepatocytes.
    Foth H; Kunellis EM; Müseler T; Kahl GF
    J Pharmacol Exp Ther; 1990 Aug; 254(2):427-32. PubMed ID: 2143535
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacokinetics and tissue distribution of 2-fluoro-beta-alanine in rats. Potential relevance to toxicity pattern of 5-fluorouracil.
    Zhang RW; Soong SJ; Liu TP; Barnes S; Diasio SB
    Drug Metab Dispos; 1992; 20(1):113-9. PubMed ID: 1346985
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile.
    Heggie GD; Sommadossi JP; Cross DS; Huster WJ; Diasio RB
    Cancer Res; 1987 Apr; 47(8):2203-6. PubMed ID: 3829006
    [TBL] [Abstract][Full Text] [Related]  

  • 9. N-chenodeoxycholyl-2-fluoro-beta-alanine: a biliary metabolite of 5-fluorouracil in humans.
    Sweeny DJ; Martin M; Diasio RB
    Drug Metab Dispos; 1988; 16(6):892-4. PubMed ID: 2907471
    [No Abstract]   [Full Text] [Related]  

  • 10. Modulation of 5-fluorouracil catabolism in isolated rat hepatocytes with enhancement of 5-fluorouracil glucuronide formation.
    Sommadossi JP; Gewirtz DA; Cross DS; Goldman ID; Cano JP; Diasio RB
    Cancer Res; 1985 Jan; 45(1):116-21. PubMed ID: 3965128
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ultrastructural localization of a fluorinated bile salt in hepatocytes.
    Crawford JM; Barnes S; Stearns RC; Hastings CL; Godleski JJ
    Lab Invest; 1994 Jul; 71(1):42-51. PubMed ID: 8041117
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conversion of liposomal 5-fluoro-2'-deoxyuridine and its dipalmitoyl derivative to bile acid conjugates of alpha-fluoro-beta-alanine and their excretion into rat bile.
    van Borssum Waalkes M; Kuipers F; Havinga R; Scherphof GL
    Biochim Biophys Acta; 1993 Mar; 1176(1-2):43-50. PubMed ID: 8452878
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolites of 5-fluorouracil in plasma and urine, as monitored by 19F nuclear magnetic resonance spectroscopy, for patients receiving chemotherapy with or without methotrexate pretreatment.
    Hull WE; Port RE; Herrmann R; Britsch B; Kunz W
    Cancer Res; 1988 Mar; 48(6):1680-8. PubMed ID: 3125967
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biological properties of the 2-fluoro-beta-alanine conjugates of cholic acid and chenodeoxycholic acid in the isolated perfused rat liver.
    Sweeny DJ; Daher G; Barnes S; Diasio RB
    Biochim Biophys Acta; 1990 Aug; 1054(1):21-5. PubMed ID: 2116908
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 19F nuclear magnetic resonance analysis of the carbamate reaction of alpha-fluoro-beta-alanine (FBAL), the major catabolite of fluoropyrimidines. Application to FBAL carbamate determination in body fluids of patients treated with 5'-deoxy-5-fluorouridine.
    Martino R; Malet-Martino MC; Vialaneix C; Lopez A; Bon M
    Drug Metab Dispos; 1987; 15(6):897-904. PubMed ID: 2893719
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of pyrimidine nucleoside phosphorylase inhibitors on hepatic fluoropyrimidine elimination in the rat.
    LaCreta FP; Warren BS; Williams WM
    Cancer Res; 1989 May; 49(10):2567-73. PubMed ID: 2523758
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Competing pathways in drug metabolism. I. Effect of input concentration on the conjugation of gentisamide in the once-through in situ perfused rat liver preparation.
    Morris ME; Yuen V; Tang BK; Pang KS
    J Pharmacol Exp Ther; 1988 May; 245(2):614-24. PubMed ID: 3367309
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Direct 19F NMR spectroscopic observation of 5-fluorouracil metabolism in the isolated perfused mouse liver model.
    Cabanac S; Malet-Martino MC; Bon M; Martino R; Nedelec JF; Dimicoli JL
    NMR Biomed; 1988 Jun; 1(3):113-20. PubMed ID: 3152774
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence for the importance of 5'-deoxy-5-fluorouridine catabolism in humans from 19F nuclear magnetic resonance spectrometry.
    Malet-Martino MC; Armand JP; Lopez A; Bernadou J; Béteille JP; Bon M; Martino R
    Cancer Res; 1986 Apr; 46(4 Pt 2):2105-12. PubMed ID: 2936452
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytotoxicity of bile salts against biliary epithelium: a study in isolated bile ductule fragments and isolated perfused rat liver.
    Benedetti A; Alvaro D; Bassotti C; Gigliozzi A; Ferretti G; La Rosa T; Di Sario A; Baiocchi L; Jezequel AM
    Hepatology; 1997 Jul; 26(1):9-21. PubMed ID: 9214446
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.