BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 29652636)

  • 1. HIF1 mediates a switch in pyruvate kinase isoforms after myocardial infarction.
    Williams AL; Khadka V; Tang M; Avelar A; Schunke KJ; Menor M; Shohet RV
    Physiol Genomics; 2018 Jul; 50(7):479-494. PubMed ID: 29652636
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ischemic heart injury leads to HIF1-dependent differential splicing of CaMK2γ.
    Williams AL; Walton CB; Pinell B; Khadka VS; Dunn B; Lee K; Anagaran MCT; Avelar A; Shohet RV
    Sci Rep; 2021 Jun; 11(1):13116. PubMed ID: 34162925
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isoform switch of pyruvate kinase M1 indeed occurs but not to pyruvate kinase M2 in human tumorigenesis.
    Zhan C; Yan L; Wang L; Ma J; Jiang W; Zhang Y; Shi Y; Wang Q
    PLoS One; 2015; 10(3):e0118663. PubMed ID: 25738776
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dietary-phytochemical mediated reversion of cancer-specific splicing inhibits Warburg effect in head and neck cancer.
    Yadav S; Bhagat SD; Gupta A; Samaiya A; Srivastava A; Shukla S
    BMC Cancer; 2019 Nov; 19(1):1031. PubMed ID: 31675998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
    Zhang H; Wang D; Li M; Plecitá-Hlavatá L; D'Alessandro A; Tauber J; Riddle S; Kumar S; Flockton A; McKeon BA; Frid MG; Reisz JA; Caruso P; El Kasmi KC; Ježek P; Morrell NW; Hu CJ; Stenmark KR
    Circulation; 2017 Dec; 136(25):2468-2485. PubMed ID: 28972001
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of Pyruvate kinase M2 (PKM2) by shikonin attenuates isoproterenol-induced acute myocardial infarction via reduction in inflammation, hypoxia, apoptosis, and fibrosis.
    Rihan M; Sharma SS
    Naunyn Schmiedebergs Arch Pharmacol; 2024 Jan; 397(1):145-159. PubMed ID: 37382601
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RBM4 Regulates Neuronal Differentiation of Mesenchymal Stem Cells by Modulating Alternative Splicing of Pyruvate Kinase M.
    Su CH; Hung KY; Hung SC; Tarn WY
    Mol Cell Biol; 2017 Feb; 37(3):. PubMed ID: 27821480
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Muscle-specific pyruvate kinase isoforms, PKM1 and PKM2, regulate mammalian SWI/SNF proteins and histone 3 phosphorylation during myoblast differentiation.
    Olea-Flores M; Sharma T; Verdejo-Torres O; DiBartolomeo I; Thompson PR; Padilla-Benavides T; Imbalzano AN
    FASEB J; 2024 Jun; 38(11):e23702. PubMed ID: 38837439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers.
    Desai S; Ding M; Wang B; Lu Z; Zhao Q; Shaw K; Yung WK; Weinstein JN; Tan M; Yao J
    Oncotarget; 2014 Sep; 5(18):8202-10. PubMed ID: 24077665
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Base editing-mediated perturbation of endogenous PKM1/2 splicing facilitates isoform-specific functional analysis in vitro and in vivo.
    Lin J; Wu S; Shen Q; Liu J; Huang S; Peng G; Qiao Y
    Cell Prolif; 2021 Aug; 54(8):e13096. PubMed ID: 34240779
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SRSF3, a Splicer of the PKM Gene, Regulates Cell Growth and Maintenance of Cancer-Specific Energy Metabolism in Colon Cancer Cells.
    Kuranaga Y; Sugito N; Shinohara H; Tsujino T; Taniguchi K; Komura K; Ito Y; Soga T; Akao Y
    Int J Mol Sci; 2018 Oct; 19(10):. PubMed ID: 30279379
    [TBL] [Abstract][Full Text] [Related]  

  • 12. No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis.
    Bluemlein K; Grüning NM; Feichtinger RG; Lehrach H; Kofler B; Ralser M
    Oncotarget; 2011 May; 2(5):393-400. PubMed ID: 21789790
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA.
    Chen M; Zhang J; Manley JL
    Cancer Res; 2010 Nov; 70(22):8977-80. PubMed ID: 20978194
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer.
    David CJ; Chen M; Assanah M; Canoll P; Manley JL
    Nature; 2010 Jan; 463(7279):364-8. PubMed ID: 20010808
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The emerging role of PKM in keratinocyte homeostasis and pathophysiology.
    Demeter JB; Elshaarrawi A; Dowker-Key PD; Bettaieb A
    FEBS J; 2023 May; 290(9):2311-2319. PubMed ID: 36541050
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pyruvate kinase M1 regulates butyrate metabolism in cancerous colonocytes.
    Park B; Kim JY; Riffey OF; Dowker-Key P; Bruckbauer A; McLoughlin J; Bettaieb A; Donohoe DR
    Sci Rep; 2022 May; 12(1):8771. PubMed ID: 35610475
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase.
    Gu Z; Xia J; Xu H; Frech I; Tricot G; Zhan F
    J Hematol Oncol; 2017 Jan; 10(1):17. PubMed ID: 28086949
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing.
    Zhu S; Chen W; Wang J; Qi L; Pan H; Feng Z; Tian D
    Theranostics; 2021; 11(7):3359-3375. PubMed ID: 33537092
    [No Abstract]   [Full Text] [Related]  

  • 19. Modulation of PKM alternative splicing by PTBP1 promotes gemcitabine resistance in pancreatic cancer cells.
    Calabretta S; Bielli P; Passacantilli I; Pilozzi E; Fendrich V; Capurso G; Fave GD; Sette C
    Oncogene; 2016 Apr; 35(16):2031-9. PubMed ID: 26234680
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth.
    Ma WK; Voss DM; Scharner J; Costa ASH; Lin KT; Jeon HY; Wilkinson JE; Jackson M; Rigo F; Bennett CF; Krainer AR
    Cancer Res; 2022 Mar; 82(5):900-915. PubMed ID: 34921016
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.