BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 29654976)

  • 1. Mechanism of irreversible inhibition of Mycobacterium tuberculosis shikimate kinase by ilimaquinone.
    Simithy J; Fuanta NR; Hobrath JV; Kochanowska-Karamyan A; Hamann MT; Goodwin DC; Calderón AI
    Biochim Biophys Acta Proteins Proteom; 2018; 1866(5-6):731-739. PubMed ID: 29654976
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of an ESI-LC-MS-based assay for kinetic evaluation of Mycobacterium tuberculosis shikimate kinase activity and inhibition.
    Simithy J; Gill G; Wang Y; Goodwin DC; Calderón AI
    Anal Chem; 2015 Feb; 87(4):2129-36. PubMed ID: 25629762
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of shikimate kinase inhibitors among anti-Mycobacterium tuberculosis compounds by LC-MS.
    Simithy J; Reeve N; Hobrath JV; Reynolds RC; Calderón AI
    Tuberculosis (Edinb); 2014 Mar; 94(2):152-8. PubMed ID: 24429106
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The mode of action of recombinant Mycobacterium tuberculosis shikimate kinase: kinetics and thermodynamics analyses.
    Rosado LA; Vasconcelos IB; Palma MS; Frappier V; Najmanovich RJ; Santos DS; Basso LA
    PLoS One; 2013; 8(5):e61918. PubMed ID: 23671579
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Screening of antitubercular compound library identifies novel shikimate kinase inhibitors of Mycobacterium tuberculosis.
    Rajput VS; Mehra R; Kumar S; Nargotra A; Singh PP; Khan IA
    Appl Microbiol Biotechnol; 2016 Jun; 100(12):5415-26. PubMed ID: 26887318
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of Mycobacterium tuberculosis shikimate kinase in complex with shikimic acid and an ATP analogue.
    Gan J; Gu Y; Li Y; Yan H; Ji X
    Biochemistry; 2006 Jul; 45(28):8539-45. PubMed ID: 16834327
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-based prediction of Mycobacterium tuberculosis shikimate kinase inhibitors by high-throughput virtual screening.
    Segura-Cabrera A; Rodríguez-Pérez MA
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3152-7. PubMed ID: 18486472
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Benzothiazole Derivative as a Novel Mycobacterium tuberculosis Shikimate Kinase Inhibitor: Identification and Elucidation of Its Allosteric Mode of Inhibition.
    Mehra R; Rajput VS; Gupta M; Chib R; Kumar A; Wazir P; Khan IA; Nargotra A
    J Chem Inf Model; 2016 May; 56(5):930-40. PubMed ID: 27149193
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Slow-Binding Inhibition of Mycobacterium tuberculosis Shikimate Kinase by Manzamine Alkaloids.
    Simithy J; Fuanta NR; Alturki M; Hobrath JV; Wahba AE; Pina I; Rath J; Hamann MT; DeRuiter J; Goodwin DC; Calderón AI
    Biochemistry; 2018 Aug; 57(32):4923-4933. PubMed ID: 30063132
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Shikimate kinase, a protein target for drug design.
    Coracini JD; de Azevedo WF
    Curr Med Chem; 2014; 21(5):592-604. PubMed ID: 24164195
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sclerotiorin inhibits protein kinase G from Mycobacterium tuberculosis and impairs mycobacterial growth in macrophages.
    Chen D; Ma S; He L; Yuan P; She Z; Lu Y
    Tuberculosis (Edinb); 2017 Mar; 103():37-43. PubMed ID: 28237032
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of an ultrafiltration-liquid chromatography/mass spectrometry (UF-LC/MS) based ligand-binding assay and an LC/MS based functional assay for Mycobacterium tuberculosis shikimate kinase.
    Mulabagal V; Calderón AI
    Anal Chem; 2010 May; 82(9):3616-21. PubMed ID: 20394394
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interaction of shikimic acid with shikimate kinase.
    Pereira JH; de Oliveira JS; Canduri F; Dias MV; Palma MS; Basso LA; de Azevedo WF; Santos DS
    Biochem Biophys Res Commun; 2004 Dec; 325(1):10-7. PubMed ID: 15522194
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Shikimate kinase (EC 2.7.1.71) from Mycobacterium tuberculosis: kinetics and structural dynamics of a potential molecular target for drug development.
    Saidemberg DM; Passarelli AW; Rodrigues AV; Basso LA; Santos DS; Palma MS
    Curr Med Chem; 2011; 18(9):1299-310. PubMed ID: 21366533
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid.
    Pereira JH; de Oliveira JS; Canduri F; Dias MV; Palma MS; Basso LA; Santos DS; de Azevedo WF
    Acta Crystallogr D Biol Crystallogr; 2004 Dec; 60(Pt 12 Pt 2):2310-9. PubMed ID: 15583379
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of a novel inhibitor of isocitrate lyase as a potent antitubercular agent against both active and non-replicating Mycobacterium tuberculosis.
    Liu Y; Zhou S; Deng Q; Li X; Meng J; Guan Y; Li C; Xiao C
    Tuberculosis (Edinb); 2016 Mar; 97():38-46. PubMed ID: 26980494
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ilimaquinone Induces the Apoptotic Cell Death of Cancer Cells by Reducing Pyruvate Dehydrogenase Kinase 1 Activity.
    Kwak CH; Jin L; Han JH; Han CW; Kim E; Cho M; Chung TW; Bae SJ; Jang SB; Ha KT
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32825675
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis.
    Gu Y; Reshetnikova L; Li Y; Wu Y; Yan H; Singh S; Ji X
    J Mol Biol; 2002 Jun; 319(3):779-89. PubMed ID: 12054870
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase.
    Alturki MS; Fuanta NR; Jarrard MA; Hobrath JV; Goodwin DC; Rants'o TA; Calderón AI
    Bioorg Med Chem Lett; 2018 Feb; 28(4):802-808. PubMed ID: 29366649
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LC-MS metabolite fingerprinting and MtSK-based screening of an endophyte Bartalinia pondoensis Marinc of Citrus aurantum L.
    Zaher AM; Makboul MA; Moharram AM; Calderón AI
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Nov; 970():18-23. PubMed ID: 25222744
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.