214 related articles for article (PubMed ID: 29659837)
1. Noonan syndrome-causing SHP2 mutants impair ERK-dependent chondrocyte differentiation during endochondral bone growth.
Tajan M; Pernin-Grandjean J; Beton N; Gennero I; Capilla F; Neel BG; Araki T; Valet P; Tauber M; Salles JP; Yart A; Edouard T
Hum Mol Genet; 2018 Jul; 27(13):2276-2289. PubMed ID: 29659837
[TBL] [Abstract][Full Text] [Related]
2. Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature.
De Rocca Serra-Nédélec A; Edouard T; Tréguer K; Tajan M; Araki T; Dance M; Mus M; Montagner A; Tauber M; Salles JP; Valet P; Neel BG; Raynal P; Yart A
Proc Natl Acad Sci U S A; 2012 Mar; 109(11):4257-62. PubMed ID: 22371576
[TBL] [Abstract][Full Text] [Related]
3. SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates.
Bowen ME; Ayturk UM; Kurek KC; Yang W; Warman ML
PLoS Genet; 2014; 10(5):e1004364. PubMed ID: 24875294
[TBL] [Abstract][Full Text] [Related]
4. Noonan and LEOPARD syndrome Shp2 variants induce heart displacement defects in zebrafish.
Bonetti M; Paardekooper Overman J; Tessadori F; Noël E; Bakkers J; den Hertog J
Development; 2014 May; 141(9):1961-70. PubMed ID: 24718990
[TBL] [Abstract][Full Text] [Related]
5. Structural insights into Noonan/LEOPARD syndrome-related mutants of protein-tyrosine phosphatase SHP2 (PTPN11).
Qiu W; Wang X; Romanov V; Hutchinson A; Lin A; Ruzanov M; Battaile KP; Pai EF; Neel BG; Chirgadze NY
BMC Struct Biol; 2014 Mar; 14():10. PubMed ID: 24628801
[TBL] [Abstract][Full Text] [Related]
6. Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome.
Krenz M; Gulick J; Osinska HE; Colbert MC; Molkentin JD; Robbins J
Proc Natl Acad Sci U S A; 2008 Dec; 105(48):18930-5. PubMed ID: 19017799
[TBL] [Abstract][Full Text] [Related]
7. Noonan syndrome mutation Q79R in Shp2 increases proliferation of valve primordia mesenchymal cells via extracellular signal-regulated kinase 1/2 signaling.
Krenz M; Yutzey KE; Robbins J
Circ Res; 2005 Oct; 97(8):813-20. PubMed ID: 16166557
[TBL] [Abstract][Full Text] [Related]
8. SHP2 sails from physiology to pathology.
Tajan M; de Rocca Serra A; Valet P; Edouard T; Yart A
Eur J Med Genet; 2015 Oct; 58(10):509-25. PubMed ID: 26341048
[TBL] [Abstract][Full Text] [Related]
9. Involvement of EphA2-mediated tyrosine phosphorylation of Shp2 in Shp2-regulated activation of extracellular signal-regulated kinase.
Miura K; Wakayama Y; Tanino M; Orba Y; Sawa H; Hatakeyama M; Tanaka S; Sabe H; Mochizuki N
Oncogene; 2013 Nov; 32(45):5292-301. PubMed ID: 23318428
[TBL] [Abstract][Full Text] [Related]
10. SHP2 Regulates the Osteogenic Fate of Growth Plate Hypertrophic Chondrocytes.
Wang L; Huang J; Moore DC; Zuo C; Wu Q; Xie L; von der Mark K; Yuan X; Chen D; Warman ML; Ehrlich MG; Yang W
Sci Rep; 2017 Oct; 7(1):12699. PubMed ID: 28983104
[TBL] [Abstract][Full Text] [Related]
11. Liver X Receptor activation delays chondrocyte hypertrophy during endochondral bone growth.
Sun MM; Beier F
Osteoarthritis Cartilage; 2014 Jul; 22(7):996-1006. PubMed ID: 24852699
[TBL] [Abstract][Full Text] [Related]
12. Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation.
Fragale A; Tartaglia M; Wu J; Gelb BD
Hum Mutat; 2004 Mar; 23(3):267-77. PubMed ID: 14974085
[TBL] [Abstract][Full Text] [Related]
13. Insulin-like growth factor-I signaling is modified during chondrocyte differentiation.
Phornphutkul C; Wu KY; Yang X; Chen Q; Gruppuso PA
J Endocrinol; 2004 Dec; 183(3):477-86. PubMed ID: 15590974
[TBL] [Abstract][Full Text] [Related]
14. Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.
Chen YN; LaMarche MJ; Chan HM; Fekkes P; Garcia-Fortanet J; Acker MG; Antonakos B; Chen CH; Chen Z; Cooke VG; Dobson JR; Deng Z; Fei F; Firestone B; Fodor M; Fridrich C; Gao H; Grunenfelder D; Hao HX; Jacob J; Ho S; Hsiao K; Kang ZB; Karki R; Kato M; Larrow J; La Bonte LR; Lenoir F; Liu G; Liu S; Majumdar D; Meyer MJ; Palermo M; Perez L; Pu M; Price E; Quinn C; Shakya S; Shultz MD; Slisz J; Venkatesan K; Wang P; Warmuth M; Williams S; Yang G; Yuan J; Zhang JH; Zhu P; Ramsey T; Keen NJ; Sellers WR; Stams T; Fortin PD
Nature; 2016 Jul; 535(7610):148-52. PubMed ID: 27362227
[TBL] [Abstract][Full Text] [Related]
15. Signaling mechanisms leading to regulation of proliferation and differentiation of the mesenchymal chondrogenic cell line RCJ3.1C5.18 in response to IGF-I.
Ciarmatori S; Kiepe D; Haarmann A; Huegel U; Tönshoff B
J Mol Endocrinol; 2007 Apr; 38(4):493-508. PubMed ID: 17446238
[TBL] [Abstract][Full Text] [Related]
16. Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome.
Nakamura T; Colbert M; Krenz M; Molkentin JD; Hahn HS; Dorn GW; Robbins J
J Clin Invest; 2007 Aug; 117(8):2123-32. PubMed ID: 17641779
[TBL] [Abstract][Full Text] [Related]
17. The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation.
Ulici V; Hoenselaar KD; Gillespie JR; Beier F
BMC Dev Biol; 2008 Apr; 8():40. PubMed ID: 18405384
[TBL] [Abstract][Full Text] [Related]
18. BDNF alters ERK/p38 MAPK activity ratios to promote differentiation in growth plate chondrocytes.
Hutchison MR
Mol Endocrinol; 2012 Aug; 26(8):1406-16. PubMed ID: 22700586
[TBL] [Abstract][Full Text] [Related]
19. Unveiling the Molecular Basis of the Noonan Syndrome-Causing Mutation T42A of SHP2.
Toto A; Malagrinò F; Visconti L; Troilo F; Gianni S
Int J Mol Sci; 2020 Jan; 21(2):. PubMed ID: 31936901
[TBL] [Abstract][Full Text] [Related]
20. Excitatory neuron-specific SHP2-ERK signaling network regulates synaptic plasticity and memory.
Ryu HH; Kim T; Kim JW; Kang M; Park P; Kim YG; Kim H; Ha J; Choi JE; Lee J; Lim CS; Kim CH; Kim SJ; Silva AJ; Kaang BK; Lee YS
Sci Signal; 2019 Mar; 12(571):. PubMed ID: 30837304
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
