BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

469 related articles for article (PubMed ID: 29663862)

  • 1. Dynamics and structural stability effects of germline PTEN mutations associated with cancer versus autism phenotypes.
    Smith IN; Thacker S; Jaini R; Eng C
    J Biomol Struct Dyn; 2019 Apr; 37(7):1766-1782. PubMed ID: 29663862
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer.
    Smith IN; Thacker S; Seyfi M; Cheng F; Eng C
    Am J Hum Genet; 2019 May; 104(5):861-878. PubMed ID: 31006514
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparative Protein Structural Network Analysis Reveals C-Terminal Tail Phosphorylation Structural Communication Fingerprint in
    Smith IN; Dawson JE; Eng C
    J Phys Chem B; 2023 Jan; 127(3):634-647. PubMed ID: 36626331
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Copy Number Variation and Clinical Outcomes in Patients With Germline PTEN Mutations.
    Yehia L; Seyfi M; Niestroj LM; Padmanabhan R; Ni Y; Frazier TW; Lal D; Eng C
    JAMA Netw Open; 2020 Jan; 3(1):e1920415. PubMed ID: 32003824
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes.
    Rodríguez-Escudero I; Oliver MD; Andrés-Pons A; Molina M; Cid VJ; Pulido R
    Hum Mol Genet; 2011 Nov; 20(21):4132-42. PubMed ID: 21828076
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a PTEN mutation with reduced protein stability, phosphatase activity, and nuclear localization in Hong Kong patients with autistic features, neurodevelopmental delays, and macrocephaly.
    Wong CW; Or PMY; Wang Y; Li L; Li J; Yan M; Cao Y; Luk HM; Tong TMF; Leslie NR; Lo IF; Choy KW; Chan AML
    Autism Res; 2018 Aug; 11(8):1098-1109. PubMed ID: 29608813
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer.
    Smith IN; Briggs JM
    Proteins; 2016 Nov; 84(11):1625-1643. PubMed ID: 27481051
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential cell cycle checkpoint evasion by PTEN germline mutations associated with dichotomous phenotypes of cancer versus autism spectrum disorder.
    Hitomi M; Venegas J; Kang SC; Eng C
    Oncogene; 2023 Dec; 42(50):3698-3707. PubMed ID: 37907589
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A pathogenic role for germline PTEN variants which accumulate into the nucleus.
    Mingo J; Rodríguez-Escudero I; Luna S; Fernández-Acero T; Amo L; Jonasson AR; Zori RT; López JI; Molina M; Cid VJ; Pulido R
    Eur J Hum Genet; 2018 Aug; 26(8):1180-1187. PubMed ID: 29706633
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Behavioural and psychological features of PTEN mutations: a systematic review of the literature and meta-analysis of the prevalence of autism spectrum disorder characteristics.
    Cummings K; Watkins A; Jones C; Dias R; Welham A
    J Neurodev Disord; 2022 Jan; 14(1):1. PubMed ID: 34983360
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prevalence and clinical/molecular characteristics of PTEN mutations in Turkish children with autism spectrum disorders and macrocephaly.
    Kaymakcalan H; Kaya İ; Cevher Binici N; Nikerel E; Özbaran B; Görkem Aksoy M; Erbilgin S; Özyurt G; Jahan N; Çelik D; Yararbaş K; Yalçınkaya L; Köse S; Durak S; Ercan-Sencicek AG
    Mol Genet Genomic Med; 2021 Aug; 9(8):e1739. PubMed ID: 34268892
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Saturation Mutagenesis Approach to Understanding PTEN Lipid Phosphatase Activity and Genotype-Phenotype Relationships.
    Mighell TL; Evans-Dutson S; O'Roak BJ
    Am J Hum Genet; 2018 May; 102(5):943-955. PubMed ID: 29706350
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder.
    Tilot AK; Frazier TW; Eng C
    Neurotherapeutics; 2015 Jul; 12(3):609-19. PubMed ID: 25916396
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Imaging of PTEN-related abnormalities in the central nervous system.
    Dhamija R; Hoxworth JM
    Clin Imaging; 2020 Apr; 60(2):180-185. PubMed ID: 31927175
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The mitochondrial genome as a modifier of autism versus cancer phenotypes in
    Wei R; Yehia L; Ni Y; Eng C
    HGG Adv; 2023 Jul; 4(3):100199. PubMed ID: 37216009
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships.
    Mighell TL; Thacker S; Fombonne E; Eng C; O'Roak BJ
    Am J Hum Genet; 2020 Jun; 106(6):818-829. PubMed ID: 32442409
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neurobehavioral phenotype of autism spectrum disorder associated with germline heterozygous mutations in PTEN.
    Busch RM; Srivastava S; Hogue O; Frazier TW; Klaas P; Hardan A; Martinez-Agosto JA; Sahin M; Eng C;
    Transl Psychiatry; 2019 Oct; 9(1):253. PubMed ID: 31594918
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular and phenotypic abnormalities in individuals with germline heterozygous PTEN mutations and autism.
    Frazier TW; Embacher R; Tilot AK; Koenig K; Mester J; Eng C
    Mol Psychiatry; 2015 Sep; 20(9):1132-8. PubMed ID: 25288137
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes.
    Spinelli L; Black FM; Berg JN; Eickholt BJ; Leslie NR
    J Med Genet; 2015 Feb; 52(2):128-34. PubMed ID: 25527629
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cross-level analysis of molecular and neurobehavioral function in a prospective series of patients with germline heterozygous PTEN mutations with and without autism.
    Frazier TW; Jaini R; Busch RM; Wolf M; Sadler T; Klaas P; Hardan AY; Martinez-Agosto JA; Sahin M; Eng C;
    Mol Autism; 2021 Jan; 12(1):5. PubMed ID: 33509259
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.