94 related articles for article (PubMed ID: 29667825)
1. Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
Kulén M; Lindgren M; Hansen S; Cairns AG; Grundström C; Begum A; van der Lingen I; Brännström K; Hall M; Sauer UH; Johansson J; Sauer-Eriksson AE; Almqvist F
J Med Chem; 2018 May; 61(9):4165-4175. PubMed ID: 29667825
[TBL] [Abstract][Full Text] [Related]
2. Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA.
Good JA; Andersson C; Hansen S; Wall J; Krishnan KS; Begum A; Grundström C; Niemiec MS; Vaitkevicius K; Chorell E; Wittung-Stafshede P; Sauer UH; Sauer-Eriksson AE; Almqvist F; Johansson J
Cell Chem Biol; 2016 Mar; 23(3):404-14. PubMed ID: 26991105
[TBL] [Abstract][Full Text] [Related]
3. The mutation G145S in PrfA, a key virulence regulator of Listeria monocytogenes, increases DNA-binding affinity by stabilizing the HTH motif.
Eiting M; Hagelüken G; Schubert WD; Heinz DW
Mol Microbiol; 2005 Apr; 56(2):433-46. PubMed ID: 15813735
[TBL] [Abstract][Full Text] [Related]
4. Free Fatty Acids Interfere with the DNA Binding Activity of the Virulence Regulator PrfA of Listeria monocytogenes.
Dos Santos PT; Thomasen RSS; Green MS; Færgeman NJ; Kallipolitis BH
J Bacteriol; 2020 Jul; 202(15):. PubMed ID: 32393522
[TBL] [Abstract][Full Text] [Related]
5. A naturally occurring mutation K220T in the pleiotropic activator PrfA of Listeria monocytogenes results in a loss of virulence due to decreasing DNA-binding affinity.
Velge P; Herler M; Johansson J; Roche SM; Témoin S; Fedorov AA; Gracieux P; Almo SC; Goebel W; Cossart P
Microbiology (Reading); 2007 Apr; 153(Pt 4):995-1005. PubMed ID: 17379709
[TBL] [Abstract][Full Text] [Related]
6. A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes.
Hansen S; Hall M; Grundström C; Brännström K; Sauer-Eriksson AE; Johansson J
J Bacteriol; 2020 May; 202(11):. PubMed ID: 32179627
[No Abstract] [Full Text] [Related]
7. A Highly Substituted Ring-Fused 2-Pyridone Compound Targeting PrfA and the Efflux Regulator BrtA in Listeria monocytogenes.
Tükenmez H; Singh P; Sarkar S; Çakır M; Oliveira AH; Lindgren C; Vaitkevicius K; Bonde M; Sauer-Eriksson AE; Almqvist F; Johansson J
mBio; 2023 Jun; 14(3):e0044923. PubMed ID: 37120759
[TBL] [Abstract][Full Text] [Related]
8. Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria.
Hall M; Grundström C; Begum A; Lindberg MJ; Sauer UH; Almqvist F; Johansson J; Sauer-Eriksson AE
Proc Natl Acad Sci U S A; 2016 Dec; 113(51):14733-14738. PubMed ID: 27930316
[TBL] [Abstract][Full Text] [Related]
9. The metabolic regulator CodY links Listeria monocytogenes metabolism to virulence by directly activating the virulence regulatory gene prfA.
Lobel L; Sigal N; Borovok I; Belitsky BR; Sonenshein AL; Herskovits AA
Mol Microbiol; 2015 Feb; 95(4):624-44. PubMed ID: 25430920
[TBL] [Abstract][Full Text] [Related]
10. New Listeria monocytogenes prfA* mutants, transcriptional properties of PrfA* proteins and structure-function of the virulence regulator PrfA.
Vega Y; Rauch M; Banfield MJ; Ermolaeva S; Scortti M; Goebel W; Vázquez-Boland JA
Mol Microbiol; 2004 Jun; 52(6):1553-65. PubMed ID: 15186408
[TBL] [Abstract][Full Text] [Related]
11. Antimicrobial medium- and long-chain free fatty acids prevent PrfA-dependent activation of virulence genes in Listeria monocytogenes.
Sternkopf Lillebæk EM; Lambert Nielsen S; Scheel Thomasen R; Færgeman NJ; Kallipolitis BH
Res Microbiol; 2017; 168(6):547-557. PubMed ID: 28344104
[TBL] [Abstract][Full Text] [Related]
12. Probing the role of protein surface charge in the activation of PrfA, the central regulator of Listeria monocytogenes pathogenesis.
Xayarath B; Volz KW; Smart JI; Freitag NE
PLoS One; 2011; 6(8):e23502. PubMed ID: 21858145
[TBL] [Abstract][Full Text] [Related]
13. Functional impact of mutational activation on the Listeria monocytogenes central virulence regulator PrfA.
Miner MD; Port GC; Freitag NE
Microbiology (Reading); 2008 Nov; 154(Pt 11):3579-3589. PubMed ID: 18957610
[TBL] [Abstract][Full Text] [Related]
14. A single substitution in the putative helix-turn-helix motif of the pleiotropic activator PrfA attenuates Listeria monocytogenes virulence.
Sheehan B; Klarsfeld A; Ebright R; Cossart P
Mol Microbiol; 1996 May; 20(4):785-97. PubMed ID: 8793875
[TBL] [Abstract][Full Text] [Related]
15. Allosteric mutants show that PrfA activation is dispensable for vacuole escape but required for efficient spread and Listeria survival in vivo.
Deshayes C; Bielecka MK; Cain RJ; Scortti M; de las Heras A; Pietras Z; Luisi BF; Núñez Miguel R; Vázquez-Boland JA
Mol Microbiol; 2012 Aug; 85(3):461-77. PubMed ID: 22646689
[TBL] [Abstract][Full Text] [Related]
16. Structural insights into glutathione-mediated activation of the master regulator PrfA in Listeria monocytogenes.
Wang Y; Feng H; Zhu Y; Gao P
Protein Cell; 2017 Apr; 8(4):308-312. PubMed ID: 28271443
[No Abstract] [Full Text] [Related]
17. Negative control of Listeria monocytogenes virulence genes by a diffusible autorepressor.
Ermolaeva S; Novella S; Vega Y; Ripio MT; Scortti M; Vázquez-Boland JA
Mol Microbiol; 2004 Apr; 52(2):601-11. PubMed ID: 15066044
[TBL] [Abstract][Full Text] [Related]
18. Glucose-1-phosphate utilization by Listeria monocytogenes is PrfA dependent and coordinately expressed with virulence factors.
Ripio MT; Brehm K; Lara M; Suárez M; Vázquez-Boland JA
J Bacteriol; 1997 Nov; 179(22):7174-80. PubMed ID: 9371468
[TBL] [Abstract][Full Text] [Related]
19. Spontaneous Loss of Virulence in Natural Populations of Listeria monocytogenes.
Maury MM; Chenal-Francisque V; Bracq-Dieye H; Han L; Leclercq A; Vales G; Moura A; Gouin E; Scortti M; Disson O; Vázquez-Boland JA; Lecuit M
Infect Immun; 2017 Nov; 85(11):. PubMed ID: 28827366
[TBL] [Abstract][Full Text] [Related]
20. How can naturally occurring fatty acids neutralize Listeria?
Kallipolitis BH
Future Microbiol; 2017 Nov; 12():1239-1241. PubMed ID: 28975811
[No Abstract] [Full Text] [Related]
[Next] [New Search]