These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life. Jiménez JA; Ptacek TS; Tuttle AH; Schmid RS; Moy SS; Simon JM; Zylka MJ Mol Autism; 2020 Oct; 11(1):74. PubMed ID: 33023670 [TBL] [Abstract][Full Text] [Related]
5. Oligodendrocyte dysfunction due to Chd8 mutation gives rise to behavioral deficits in mice. Kawamura A; Katayama Y; Nishiyama M; Shoji H; Tokuoka K; Ueta Y; Miyata M; Isa T; Miyakawa T; Hayashi-Takagi A; Nakayama KI Hum Mol Genet; 2020 May; 29(8):1274-1291. PubMed ID: 32142125 [TBL] [Abstract][Full Text] [Related]
6. Arid1b Haploinsufficiency Causes Abnormal Brain Gene Expression and Autism-Related Behaviors in Mice. Shibutani M; Horii T; Shoji H; Morita S; Kimura M; Terawaki N; Miyakawa T; Hatada I Int J Mol Sci; 2017 Aug; 18(9):. PubMed ID: 28867767 [TBL] [Abstract][Full Text] [Related]
7. CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors. Sugathan A; Biagioli M; Golzio C; Erdin S; Blumenthal I; Manavalan P; Ragavendran A; Brand H; Lucente D; Miles J; Sheridan SD; Stortchevoi A; Kellis M; Haggarty SJ; Katsanis N; Gusella JF; Talkowski ME Proc Natl Acad Sci U S A; 2014 Oct; 111(42):E4468-77. PubMed ID: 25294932 [TBL] [Abstract][Full Text] [Related]
8. Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain. Kawamura A; Abe Y; Seki F; Katayama Y; Nishiyama M; Takata N; Tanaka KF; Okano H; Nakayama KI Mol Brain; 2020 Nov; 13(1):160. PubMed ID: 33228730 [TBL] [Abstract][Full Text] [Related]
10. CHD8 regulates gut epithelial cell function and affects autism-related behaviors through the gut-brain axis. Chatterjee I; Getselter D; Ghanayem N; Harari R; Davis L; Bel S; Elliott E Transl Psychiatry; 2023 Oct; 13(1):305. PubMed ID: 37783686 [TBL] [Abstract][Full Text] [Related]
11. The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment. Cotney J; Muhle RA; Sanders SJ; Liu L; Willsey AJ; Niu W; Liu W; Klei L; Lei J; Yin J; Reilly SK; Tebbenkamp AT; Bichsel C; Pletikos M; Sestan N; Roeder K; State MW; Devlin B; Noonan JP Nat Commun; 2015 Mar; 6():6404. PubMed ID: 25752243 [TBL] [Abstract][Full Text] [Related]
12. Excitatory neuronal CHD8 in the regulation of neocortical development and sensory-motor behaviors. Kweon H; Jung WB; Im GH; Ryoo J; Lee JH; Do H; Choi Y; Song YH; Jung H; Park H; Qiu LR; Ellegood J; Shim HJ; Yang E; Kim H; Lerch JP; Lee SH; Chung WS; Kim D; Kim SG; Kim E Cell Rep; 2021 Feb; 34(8):108780. PubMed ID: 33626347 [TBL] [Abstract][Full Text] [Related]
13. CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells. Wang P; Mokhtari R; Pedrosa E; Kirschenbaum M; Bayrak C; Zheng D; Lachman HM Mol Autism; 2017; 8():11. PubMed ID: 28321286 [TBL] [Abstract][Full Text] [Related]
14. Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits. Platt RJ; Zhou Y; Slaymaker IM; Shetty AS; Weisbach NR; Kim JA; Sharma J; Desai M; Sood S; Kempton HR; Crabtree GR; Feng G; Zhang F Cell Rep; 2017 Apr; 19(2):335-350. PubMed ID: 28402856 [TBL] [Abstract][Full Text] [Related]
15. Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants. Siu MT; Butcher DT; Turinsky AL; Cytrynbaum C; Stavropoulos DJ; Walker S; Caluseriu O; Carter M; Lou Y; Nicolson R; Georgiades S; Szatmari P; Anagnostou E; Scherer SW; Choufani S; Brudno M; Weksberg R Clin Epigenetics; 2019 Jul; 11(1):103. PubMed ID: 31311581 [TBL] [Abstract][Full Text] [Related]
16. Developmental pyrethroid exposure and age influence phenotypes in a Chd8 haploinsufficient autism mouse model. Jiménez JA; Simon JM; Hu W; Moy SS; Harper KM; Liu CW; Lu K; Zylka MJ Sci Rep; 2022 Apr; 12(1):5555. PubMed ID: 35365720 [TBL] [Abstract][Full Text] [Related]
17. Chd8 haploinsufficiency impacts rearing experience in C57BL/6 mice. Tabbaa M; Levitt P Genes Brain Behav; 2024 Apr; 23(2):e12892. PubMed ID: 38560770 [TBL] [Abstract][Full Text] [Related]
18. Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex. Ellingford RA; Tojo M; Basson MA; Andreae LC ACS Chem Neurosci; 2024 Apr; 15(8):1635-1642. PubMed ID: 38557009 [No Abstract] [Full Text] [Related]
19. Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism. Cherepanov SM; Gerasimenko M; Yuhi T; Furuhara K; Tsuji C; Yokoyama S; Nakayama KI; Nishiyama M; Higashida H BMC Neurosci; 2021 May; 22(1):32. PubMed ID: 33933000 [TBL] [Abstract][Full Text] [Related]