BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 29668931)

  • 1. TRAF2 and TRAF5 associated with the signal transducing receptor gp130 limit IL-6-driven transphosphorylation of JAK1 through the inhibition of proximal JAK-JAK interaction.
    Kimura M; Nagashima H; Okuyama Y; Ishii N; So T
    Int Immunol; 2018 Jun; 30(7):291-299. PubMed ID: 29668931
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of Interleukin-6 Receptor Signaling by TNF Receptor-Associated Factor 2 and 5 During Differentiation of Inflammatory CD4
    Nagashima H; Ishii N; So T
    Front Immunol; 2018; 9():1986. PubMed ID: 30214449
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development.
    Nagashima H; Okuyama Y; Hayashi T; Ishii N; So T
    J Immunol; 2016 May; 196(10):4082-9. PubMed ID: 27076680
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Immune Regulation by TNF Receptor-associated Factor 5].
    So T
    Yakugaku Zasshi; 2024; 144(5):489-496. PubMed ID: 38692922
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F; Gendo C; Eck M; Schmitz J; Grimm C; Anhuf D; Kerr IM; Heinrich PC
    Biochem J; 1998 Nov; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TNF Receptor-Associated Factor 5 Limits IL-27 Receptor Signaling in CD4
    Kawahara E; Azuma M; Nagashima H; Omori K; Akiyama S; Fujimori Y; Oishi M; Shibui N; Kawaguchi K; Morita M; Okuyama Y; Ishii N; So T
    J Immunol; 2022 Feb; 208(3):642-650. PubMed ID: 34996840
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6.
    Nagashima H; Okuyama Y; Asao A; Kawabe T; Yamaki S; Nakano H; Croft M; Ishii N; So T
    Nat Immunol; 2014 May; 15(5):449-56. PubMed ID: 24681564
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytokine receptor signaling is required for the survival of ALK- anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations.
    Chen J; Zhang Y; Petrus MN; Xiao W; Nicolae A; Raffeld M; Pittaluga S; Bamford RN; Nakagawa M; Ouyang ST; Epstein AL; Kadin ME; Del Mistro A; Woessner R; Jaffe ES; Waldmann TA
    Proc Natl Acad Sci U S A; 2017 Apr; 114(15):3975-3980. PubMed ID: 28356514
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.
    Fujitani Y; Hibi M; Fukada T; Takahashi-Tezuka M; Yoshida H; Yamaguchi T; Sugiyama K; Yamanaka Y; Nakajima K; Hirano T
    Oncogene; 1997 Feb; 14(7):751-61. PubMed ID: 9047382
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence that IL-6-type cytokine signaling in cardiomyocytes is inhibited by oxidative stress: parthenolide targets JAK1 activation by generating ROS.
    Kurdi M; Booz GW
    J Cell Physiol; 2007 Aug; 212(2):424-31. PubMed ID: 17385713
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes.
    Kunisada K; Hirota H; Fujio Y; Matsui H; Tani Y; Yamauchi-Takihara K; Kishimoto T
    Circulation; 1996 Nov; 94(10):2626-32. PubMed ID: 8921810
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: the receptor is crucial for kinase activation.
    Haan C; Heinrich PC; Behrmann I
    Biochem J; 2002 Jan; 361(Pt 1):105-11. PubMed ID: 11742534
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions.
    Dahmen H; Horsten U; Küster A; Jacques Y; Minvielle S; Kerr IM; Ciliberto G; Paonessa G; Heinrich PC; Müller-Newen G
    Biochem J; 1998 May; 331 ( Pt 3)(Pt 3):695-702. PubMed ID: 9560294
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Iron-dependent CDK1 activity promotes lung carcinogenesis via activation of the GP130/STAT3 signaling pathway.
    Kuang Y; Guo W; Ling J; Xu D; Liao Y; Zhao H; Du X; Wang H; Xu M; Song H; Wang T; Jing B; Li K; Hu M; Wu W; Deng J; Wang Q
    Cell Death Dis; 2019 Apr; 10(4):297. PubMed ID: 30931929
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling.
    Wolf J; Waetzig GH; Chalaris A; Reinheimer TM; Wege H; Rose-John S; Garbers C
    J Biol Chem; 2016 Jul; 291(31):16186-96. PubMed ID: 27226573
    [TBL] [Abstract][Full Text] [Related]  

  • 16. IL-6-gp130-STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state.
    Nishihara M; Ogura H; Ueda N; Tsuruoka M; Kitabayashi C; Tsuji F; Aono H; Ishihara K; Huseby E; Betz UA; Murakami M; Hirano T
    Int Immunol; 2007 Jun; 19(6):695-702. PubMed ID: 17493959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutations leading to constitutive active gp130/JAK1/STAT3 pathway.
    Pilati C; Zucman-Rossi J
    Cytokine Growth Factor Rev; 2015 Oct; 26(5):499-506. PubMed ID: 26188635
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
    Bode JG; Schweigart J; Kehrmann J; Ehlting C; Schaper F; Heinrich PC; Häussinger D
    J Immunol; 2003 Jul; 171(1):257-66. PubMed ID: 12817006
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interleukin-6 promotes proliferative vitreoretinopathy by inducing epithelial-mesenchymal transition via the JAK1/STAT3 signaling pathway.
    Chen X; Yang W; Deng X; Ye S; Xiao W
    Mol Vis; 2020; 26():517-529. PubMed ID: 32818015
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combination of interleukin-6 and soluble interleukin-6 receptors induces differentiation and activation of JAK-STAT and MAP kinase pathways in MG-63 human osteoblastic cells.
    Nishimura R; Moriyama K; Yasukawa K; Mundy GR; Yoneda T
    J Bone Miner Res; 1998 May; 13(5):777-85. PubMed ID: 9610741
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.