These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

429 related articles for article (PubMed ID: 29669855)

  • 1. Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target.
    Liu D; Wong CC; Fu L; Chen H; Zhao L; Li C; Zhou Y; Zhang Y; Xu W; Yang Y; Wu B; Cheng G; Lai PB; Wong N; Sung JJY; Yu J
    Sci Transl Med; 2018 Apr; 10(437):. PubMed ID: 29669855
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Squalene epoxidase (SQLE) promotes the growth and migration of the hepatocellular carcinoma cells.
    Sui Z; Zhou J; Cheng Z; Lu P
    Tumour Biol; 2015 Aug; 36(8):6173-9. PubMed ID: 25787749
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Squalene Epoxidase Induces Nonalcoholic Steatohepatitis Via Binding to Carbonic Anhydrase III and is a Therapeutic Target.
    Liu D; Wong CC; Zhou Y; Li C; Chen H; Ji F; Go MYY; Wang F; Su H; Wei H; Cai Z; Wong N; Wong VWS; Yu J
    Gastroenterology; 2021 Jun; 160(7):2467-2482.e3. PubMed ID: 33647280
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Squalene epoxidase-induced cholesteryl ester accumulation promotes nasopharyngeal carcinoma development by activating PI3K/AKT signaling.
    Li L; Zhang Q; Wang X; Li Y; Xie H; Chen X
    Cancer Sci; 2020 Jul; 111(7):2275-2283. PubMed ID: 32314495
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High Squalene Epoxidase in Tumors Predicts Worse Survival in Patients With Hepatocellular Carcinoma: Integrated Bioinformatic Analysis on NAFLD and HCC.
    Shen T; Lu Y; Zhang Q
    Cancer Control; 2020; 27(1):1073274820914663. PubMed ID: 32216563
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy.
    Hong Z; Liu T; Wan L; Fa P; Kumar P; Cao Y; Prasad CB; Qiu Z; Liu J; Wang H; Li Z; Wang QE; Guo P; Guo D; Yilmaz AS; Lu L; Papandreou I; Jacob NK; Yan C; Zhang X; She QB; Ma Z; Zhang J
    Cancer Res; 2022 Apr; 82(7):1298-1312. PubMed ID: 35045984
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis.
    Kodama T; Yi J; Newberg JY; Tien JC; Wu H; Finegold MJ; Kodama M; Wei Z; Tamura T; Takehara T; Johnson RL; Jenkins NA; Copeland NG
    Proc Natl Acad Sci U S A; 2018 Oct; 115(44):E10417-E10426. PubMed ID: 30327349
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis.
    Li C; Wang Y; Liu D; Wong CC; Coker OO; Zhang X; Liu C; Zhou Y; Liu Y; Kang W; To KF; Sung JJ; Yu J
    Gut; 2022 Nov; 71(11):2253-2265. PubMed ID: 35232776
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer.
    Kalogirou C; Linxweiler J; Schmucker P; Snaebjornsson MT; Schmitz W; Wach S; Krebs M; Hartmann E; Puhr M; Müller A; Spahn M; Seitz AK; Frank T; Marouf H; Büchel G; Eckstein M; Kübler H; Eilers M; Saar M; Junker K; Röhrig F; Kneitz B; Rosenfeldt MT; Schulze A
    Nat Commun; 2021 Aug; 12(1):5066. PubMed ID: 34417456
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1-mediated MAPK signaling.
    He L; Li H; Pan C; Hua Y; Peng J; Zhou Z; Zhao Y; Lin M
    Cancer Commun (Lond); 2021 Aug; 41(8):726-746. PubMed ID: 34268906
    [TBL] [Abstract][Full Text] [Related]  

  • 11. O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress.
    Xu W; Zhang X; Wu JL; Fu L; Liu K; Liu D; Chen GG; Lai PB; Wong N; Yu J
    J Hepatol; 2017 Aug; 67(2):310-320. PubMed ID: 28347804
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TUBB4B is a novel therapeutic target in non-alcoholic fatty liver disease-associated hepatocellular carcinoma.
    Yang Z; Gao S; Wong CC; Liu W; Chen H; Shang H; Wu ZY; Xu L; Zhang X; Wong N; Kuang M; Yu J
    J Pathol; 2023 May; 260(1):71-83. PubMed ID: 36787097
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase.
    Padyana AK; Gross S; Jin L; Cianchetta G; Narayanaswamy R; Wang F; Wang R; Fang C; Lv X; Biller SA; Dang L; Mahoney CE; Nagaraja N; Pirman D; Sui Z; Popovici-Muller J; Smolen GA
    Nat Commun; 2019 Jan; 10(1):97. PubMed ID: 30626872
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.
    Zhang Z; Wu W; Jiao H; Chen Y; Ji X; Cao J; Yin F; Yin W
    Br J Pharmacol; 2023 Jun; 180(12):1562-1581. PubMed ID: 36581319
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduction of Squalene Epoxidase by Cholesterol Accumulation Accelerates Colorectal Cancer Progression and Metastasis.
    Jun SY; Brown AJ; Chua NK; Yoon JY; Lee JJ; Yang JO; Jang I; Jeon SJ; Choi TI; Kim CH; Kim NS
    Gastroenterology; 2021 Mar; 160(4):1194-1207.e28. PubMed ID: 32946903
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MicroRNA expression analysis in high fat diet-induced NAFLD-NASH-HCC progression: study on C57BL/6J mice.
    Tessitore A; Cicciarelli G; Del Vecchio F; Gaggiano A; Verzella D; Fischietti M; Mastroiaco V; Vetuschi A; Sferra R; Barnabei R; Capece D; Zazzeroni F; Alesse E
    BMC Cancer; 2016 Jan; 16():3. PubMed ID: 26728044
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metformin modulates innate immune-mediated inflammation and early progression of NAFLD-associated hepatocellular carcinoma in zebrafish.
    de Oliveira S; Houseright RA; Graves AL; Golenberg N; Korte BG; Miskolci V; Huttenlocher A
    J Hepatol; 2019 Apr; 70(4):710-721. PubMed ID: 30572006
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.
    Sun H; Li L; Li W; Yang F; Zhang Z; Liu Z; Du W
    EMBO Rep; 2021 Oct; 22(10):e52537. PubMed ID: 34459531
    [TBL] [Abstract][Full Text] [Related]  

  • 19. OSBPL2 deficiency upregulate SQLE expression increasing intracellular cholesterol and cholesteryl ester by AMPK/SP1 and SREBF2 signalling pathway.
    Zhang C; Zhang H; Zhang M; Lin C; Wang H; Yao J; Wei Q; Lu Y; Chen Z; Xing G; Cao X
    Exp Cell Res; 2019 Oct; 383(2):111512. PubMed ID: 31356817
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oncogenic mutations and dysregulated pathways in obesity-associated hepatocellular carcinoma.
    Shen J; Tsoi H; Liang Q; Chu ES; Liu D; Yu AC; Chan TF; Li X; Sung JJ; Wong VW; Yu J
    Oncogene; 2016 Dec; 35(49):6271-6280. PubMed ID: 27132506
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.