BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 29670109)

  • 1. Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers.
    Guo YA; Chang MM; Huang W; Ooi WF; Xing M; Tan P; Skanderup AJ
    Nat Commun; 2018 Apr; 9(1):1520. PubMed ID: 29670109
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pan-cancer analysis of somatic mutations and epigenetic alterations in insulated neighbourhood boundaries.
    Pinoli P; Stamoulakatou E; Nguyen AP; Rodríguez Martínez M; Ceri S
    PLoS One; 2020; 15(1):e0227180. PubMed ID: 31945090
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chromatin loop anchors are associated with genome instability in cancer and recombination hotspots in the germline.
    Kaiser VB; Semple CA
    Genome Biol; 2018 Jul; 19(1):101. PubMed ID: 30060743
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of coding and non-coding mutational hotspots in cancer genomes.
    Piraino SW; Furney SJ
    BMC Genomics; 2017 Jan; 18(1):17. PubMed ID: 28056774
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CTCF/cohesin-binding sites are frequently mutated in cancer.
    Katainen R; Dave K; Pitkänen E; Palin K; Kivioja T; Välimäki N; Gylfe AE; Ristolainen H; Hänninen UA; Cajuso T; Kondelin J; Tanskanen T; Mecklin JP; Järvinen H; Renkonen-Sinisalo L; Lepistö A; Kaasinen E; Kilpivaara O; Tuupanen S; Enge M; Taipale J; Aaltonen LA
    Nat Genet; 2015 Jul; 47(7):818-21. PubMed ID: 26053496
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional and genetic determinants of mutation rate variability in regulatory elements of cancer genomes.
    Lee CA; Abd-Rabbo D; Reimand J
    Genome Biol; 2021 May; 22(1):133. PubMed ID: 33941236
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chromatin accessibility contributes to simultaneous mutations of cancer genes.
    Shi Y; Su XB; He KY; Wu BH; Zhang BY; Han ZG
    Sci Rep; 2016 Oct; 6():35270. PubMed ID: 27762310
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites.
    Yin M; Wang J; Wang M; Li X; Zhang M; Wu Q; Wang Y
    Cell Res; 2017 Nov; 27(11):1365-1377. PubMed ID: 29076501
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional Mutations Form at CTCF-Cohesin Binding Sites in Melanoma Due to Uneven Nucleotide Excision Repair across the Motif.
    Poulos RC; Thoms JAI; Guan YF; Unnikrishnan A; Pimanda JE; Wong JWH
    Cell Rep; 2016 Dec; 17(11):2865-2872. PubMed ID: 27974201
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chromosomal aberrations in primary PDGFRA-mutated gastrointestinal stromal tumors.
    Schaefer IM; Delfs C; Cameron S; Gunawan B; Agaimy A; Ghadimi BM; Haller F
    Hum Pathol; 2014 Jan; 45(1):85-97. PubMed ID: 24157063
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The landscape and driver potential of site-specific hotspots across cancer genomes.
    Juul RI; Nielsen MM; Juul M; Feuerbach L; Pedersen JS
    NPJ Genom Med; 2021 May; 6(1):33. PubMed ID: 33986299
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insertions and Deletions Target Lineage-Defining Genes in Human Cancers.
    Imielinski M; Guo G; Meyerson M
    Cell; 2017 Jan; 168(3):460-472.e14. PubMed ID: 28089356
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types.
    Chen T; Wang Z; Zhou W; Chong Z; Meric-Bernstam F; Mills GB; Chen K
    BMC Genomics; 2016 Jun; 17 Suppl 2(Suppl 2):394. PubMed ID: 27356755
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis.
    Letouzé E; Shinde J; Renault V; Couchy G; Blanc JF; Tubacher E; Bayard Q; Bacq D; Meyer V; Semhoun J; Bioulac-Sage P; Prévôt S; Azoulay D; Paradis V; Imbeaud S; Deleuze JF; Zucman-Rossi J
    Nat Commun; 2017 Nov; 8(1):1315. PubMed ID: 29101368
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes.
    Perera D; Poulos RC; Shah A; Beck D; Pimanda JE; Wong JW
    Nature; 2016 Apr; 532(7598):259-63. PubMed ID: 27075100
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genomic landscape and mutational impacts of recurrently mutated genes in cancers.
    Liu B; Hu FF; Zhang Q; Hu H; Ye Z; Tang Q; Guo AY
    Mol Genet Genomic Med; 2018 Nov; 6(6):910-923. PubMed ID: 30107644
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers.
    Umer HM; Cavalli M; Dabrowski MJ; Diamanti K; Kruczyk M; Pan G; Komorowski J; Wadelius C
    Hum Mutat; 2016 Sep; 37(9):904-13. PubMed ID: 27174533
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A system for detecting high impact-low frequency mutations in primary tumors and metastases.
    Anjanappa M; Hao Y; Simpson ER; Bhat-Nakshatri P; Nelson JB; Tersey SA; Mirmira RG; Cohen-Gadol AA; Saadatzadeh MR; Li L; Fang F; Nephew KP; Miller KD; Liu Y; Nakshatri H
    Oncogene; 2018 Jan; 37(2):185-196. PubMed ID: 28892047
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Single cell genomics reveals activation signatures of endogenous SCAR's networks in aneuploid human embryos and clinically intractable malignant tumors.
    Glinsky GV
    Cancer Lett; 2016 Oct; 381(1):176-93. PubMed ID: 27497790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutational Biases Drive Elevated Rates of Substitution at Regulatory Sites across Cancer Types.
    Kaiser VB; Taylor MS; Semple CA
    PLoS Genet; 2016 Aug; 12(8):e1006207. PubMed ID: 27490693
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.