BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

531 related articles for article (PubMed ID: 29670289)

  • 1. SAMHD1 acts at stalled replication forks to prevent interferon induction.
    Coquel F; Silva MJ; Técher H; Zadorozhny K; Sharma S; Nieminuszczy J; Mettling C; Dardillac E; Barthe A; Schmitz AL; Promonet A; Cribier A; Sarrazin A; Niedzwiedz W; Lopez B; Costanzo V; Krejci L; Chabes A; Benkirane M; Lin YL; Pasero P
    Nature; 2018 May; 557(7703):57-61. PubMed ID: 29670289
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [SAMHD1 acts at stalled replication forks to prevent interferon induction].
    Coquel F; Silva MJ; Técher H; Zadorozhny K; Sharma S; Nieminuszczy J; Mettling C; Dardillac E; Barthe A; Schmitz AL; Promonet A; Cribier A; Sarrazin A; Niedzwiedz W; Lopez B; Costanzo V; Krejci L; Chabes A; Benkirane M; Lin YL; Pasero P
    C R Biol; 2020 Jun; 343(1):9-21. PubMed ID: 32720483
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SAMHD1 and the innate immune response to cytosolic DNA during DNA replication.
    Coquel F; Neumayer C; Lin YL; Pasero P
    Curr Opin Immunol; 2019 Feb; 56():24-30. PubMed ID: 30292848
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA.
    Lyu X; Lei KH; Biak Sang P; Shiva O; Chastain M; Chi P; Chai W
    EMBO J; 2021 Jan; 40(2):e103654. PubMed ID: 33210317
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1.
    Maelfait J; Bridgeman A; Benlahrech A; Cursi C; Rehwinkel J
    Cell Rep; 2016 Aug; 16(6):1492-1501. PubMed ID: 27477283
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interference with SAMHD1 Restores Late Gene Expression of Modified Vaccinia Virus Ankara in Human Dendritic Cells and Abrogates Type I Interferon Expression.
    Sliva K; Martin J; von Rhein C; Herrmann T; Weyrich A; Toda M; Schnierle BS
    J Virol; 2019 Nov; 93(22):. PubMed ID: 31462561
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation.
    Malacaria E; Pugliese GM; Honda M; Marabitti V; Aiello FA; Spies M; Franchitto A; Pichierri P
    Nat Commun; 2019 Mar; 10(1):1412. PubMed ID: 30926821
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.
    Schumann T; Ramon SC; Schubert N; Mayo MA; Hega M; Maser KI; Ada SR; Sydow L; Hajikazemi M; Badstübner M; Müller P; Ge Y; Shakeri F; Buness A; Rupf B; Lienenklaus S; Utess B; Muhandes L; Haase M; Rupp L; Schmitz M; Gramberg T; Manel N; Hartmann G; Zillinger T; Kato H; Bauer S; Gerbaulet A; Paeschke K; Roers A; Behrendt R
    J Exp Med; 2023 Jan; 220(1):. PubMed ID: 36346347
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.
    Daddacha W; Koyen AE; Bastien AJ; Head PE; Dhere VR; Nabeta GN; Connolly EC; Werner E; Madden MZ; Daly MB; Minten EV; Whelan DR; Schlafstein AJ; Zhang H; Anand R; Doronio C; Withers AE; Shepard C; Sundaram RK; Deng X; Dynan WS; Wang Y; Bindra RS; Cejka P; Rothenberg E; Doetsch PW; Kim B; Yu DS
    Cell Rep; 2017 Aug; 20(8):1921-1935. PubMed ID: 28834754
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SAMHD1 deficient human monocytes autonomously trigger type I interferon.
    Martinez-Lopez A; Martin-Fernandez M; Buta S; Kim B; Bogunovic D; Diaz-Griffero F
    Mol Immunol; 2018 Sep; 101():450-460. PubMed ID: 30099227
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A central role for PI3K-AKT signaling pathway in linking SAMHD1-deficiency to the type I interferon signature.
    Oh C; Ryoo J; Park K; Kim B; Daly MB; Cho D; Ahn K
    Sci Rep; 2018 Jan; 8(1):84. PubMed ID: 29311560
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics.
    Orris B; Huynh KW; Ammirati M; Han S; Bolaños B; Carmody J; Petroski MD; Bosbach B; Shields DJ; Stivers JT
    Nucleic Acids Res; 2022 Jul; 50(13):7545-7559. PubMed ID: 35801923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Guanine-containing ssDNA and RNA induce dimeric and tetrameric structural forms of SAMHD1.
    Orris B; Sung MW; Bhat S; Xu Y; Huynh KW; Han S; Johnson DC; Bosbach B; Shields DJ; Stivers JT
    Nucleic Acids Res; 2023 Dec; 51(22):12443-12458. PubMed ID: 37930833
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SAMHD1-deficient fibroblasts from Aicardi-Goutières Syndrome patients can escape senescence and accumulate mutations.
    Franzolin E; Coletta S; Ferraro P; Pontarin G; D'Aronco G; Stevanoni M; Palumbo E; Cagnin S; Bertoldi L; Feltrin E; Valle G; Russo A; Bianchi V; Rampazzo C
    FASEB J; 2020 Jan; 34(1):631-647. PubMed ID: 31914608
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The KU-PARP14 axis differentially regulates DNA resection at stalled replication forks by MRE11 and EXO1.
    Dhoonmoon A; Nicolae CM; Moldovan GL
    Nat Commun; 2022 Aug; 13(1):5063. PubMed ID: 36030235
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SAMHD1 Functions and Human Diseases.
    Coggins SA; Mahboubi B; Schinazi RF; Kim B
    Viruses; 2020 Mar; 12(4):. PubMed ID: 32244340
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic Evidence for Roles of Yeast Mitotic Cyclins at Single-Stranded Gaps Created by DNA Replication.
    Signon L
    G3 (Bethesda); 2018 Feb; 8(2):737-752. PubMed ID: 29279302
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer.
    Ye Z; Xu S; Shi Y; Cheng X; Zhang Y; Roy S; Namjoshi S; Longo MA; Link TM; Schlacher K; Peng G; Yu D; Wang B; Tainer JA; Ahmed Z
    Nat Commun; 2024 Mar; 15(1):2132. PubMed ID: 38459011
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interferon-inducible SAMHD1 restricts viral replication through downregulation of lipid synthesis.
    An N; Ge Q; Shao H; Li Q; Guo F; Liang C; Li X; Yi D; Yang L; Cen S
    Front Immunol; 2022; 13():1007718. PubMed ID: 36532074
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p21 Restricts HIV-1 in Monocyte-Derived Dendritic Cells through the Reduction of Deoxynucleoside Triphosphate Biosynthesis and Regulation of SAMHD1 Antiviral Activity.
    Valle-Casuso JC; Allouch A; David A; Lenzi GM; Studdard L; Barré-Sinoussi F; Müller-Trutwin M; Kim B; Pancino G; Sáez-Cirión A
    J Virol; 2017 Dec; 91(23):. PubMed ID: 28931685
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.