BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 29672847)

  • 1. Loss of N-WASP drives early progression in an Apc model of intestinal tumourigenesis.
    Morris HT; Fort L; Spence HJ; Patel R; Vincent DF; Park JH; Snapper SB; Carey FA; Sansom OJ; Machesky LM
    J Pathol; 2018 Jul; 245(3):337-348. PubMed ID: 29672847
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.
    May S; Owen H; Phesse TJ; Greenow KR; Jones GR; Blackwood A; Cook PC; Towers C; Gallimore AM; Williams GT; Stürzl M; Britzen-Laurent N; Sansom OJ; MacDonald AS; Bird AP; Clarke AR; Parry L
    J Pathol; 2018 Jul; 245(3):270-282. PubMed ID: 29603746
    [TBL] [Abstract][Full Text] [Related]  

  • 3. APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic acid signalling in colon cancer development.
    Zhang T; Ahn K; Emerick B; Modarai SR; Opdenaker LM; Palazzo J; Schleiniger G; Fields JZ; Boman BM
    PLoS One; 2020; 15(10):e0239601. PubMed ID: 33112876
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A role for the vitamin D pathway in non-intestinal lesions in genetic and carcinogen models of colorectal cancer and in familial adenomatous polyposis.
    Bong YS; Assefnia S; Tuohy T; Neklason DW; Burt RW; Ahn J; Bueno De Mesquita PJ; Byers SW
    Oncotarget; 2016 Dec; 7(49):80508-80520. PubMed ID: 27768599
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.
    Buchert M; Rohde F; Eissmann M; Tebbutt N; Williams B; Tan CW; Owen A; Hirokawa Y; Gnann A; Orend G; Orner G; Dashwood RH; Heath JK; Ernst M; Janssen KP
    Dis Model Mech; 2015 Nov; 8(11):1361-73. PubMed ID: 26398937
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stat3 is a negative regulator of intestinal tumor progression in Apc(Min) mice.
    Musteanu M; Blaas L; Mair M; Schlederer M; Bilban M; Tauber S; Esterbauer H; Mueller M; Casanova E; Kenner L; Poli V; Eferl R
    Gastroenterology; 2010 Mar; 138(3):1003-11.e1-5. PubMed ID: 19962983
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice.
    Büller NV; Rosekrans SL; Metcalfe C; Heijmans J; van Dop WA; Fessler E; Jansen M; Ahn C; Vermeulen JL; Westendorp BF; Robanus-Maandag EC; Offerhaus GJ; Medema JP; D'Haens GR; Wildenberg ME; de Sauvage FJ; Muncan V; van den Brink GR
    Gastroenterology; 2015 Jan; 148(1):170-180.e6. PubMed ID: 25307863
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.
    Powell AE; Vlacich G; Zhao ZY; McKinley ET; Washington MK; Manning HC; Coffey RJ
    Am J Physiol Gastrointest Liver Physiol; 2014 Jul; 307(1):G16-23. PubMed ID: 24833705
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation.
    Feng Y; Sentani K; Wiese A; Sands E; Green M; Bommer GT; Cho KR; Fearon ER
    Am J Pathol; 2013 Aug; 183(2):493-503. PubMed ID: 23769888
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Elevated adenomatous polyposis coli in goblet cells is associated with inflammation in mouse and human colon.
    Gomez CL; Neufeld KL
    Exp Physiol; 2020 Dec; 105(12):2154-2167. PubMed ID: 33150708
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.
    Xiao H; Yin W; Khan MA; Gulen MF; Zhou H; Sham HP; Jacobson K; Vallance BA; Li X
    Gastroenterology; 2010 Aug; 139(2):574-85. PubMed ID: 20416302
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of HIF-1α does not increase intestinal tumorigenesis.
    Xue X; Ramakrishnan SK; Shah YM
    Am J Physiol Gastrointest Liver Physiol; 2014 Jul; 307(2):G187-95. PubMed ID: 24875099
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation.
    Radulescu S; Ridgway RA; Cordero J; Athineos D; Salgueiro P; Poulsom R; Neumann J; Jung A; Patel S; Woodgett J; Barker N; Pritchard DM; Oien K; Sansom OJ
    Oncogene; 2013 Apr; 32(16):2048-57. PubMed ID: 22665058
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intestinal Epithelial TBK1 Prevents Differentiation of T-helper 17 Cells and Tumorigenesis in Mice.
    Yang JY; Jie Z; Mathews A; Zhou X; Li Y; Gu M; Xie X; Ko CJ; Cheng X; Qi Y; Estrella JS; Wang J; Sun SC
    Gastroenterology; 2020 Nov; 159(5):1793-1806. PubMed ID: 32745468
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice.
    Lyubimova A; Garber JJ; Upadhyay G; Sharov A; Anastasoaie F; Yajnik V; Cotsarelis G; Dotto GP; Botchkarev V; Snapper SB
    J Clin Invest; 2010 Feb; 120(2):446-56. PubMed ID: 20071778
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis.
    Ghaleb AM; McConnell BB; Nandan MO; Katz JP; Kaestner KH; Yang VW
    Cancer Res; 2007 Aug; 67(15):7147-54. PubMed ID: 17671182
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhanced stem cell survival in familial adenomatous polyposis.
    Kim KM; Calabrese P; Tavaré S; Shibata D
    Am J Pathol; 2004 Apr; 164(4):1369-77. PubMed ID: 15039224
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expansion of a mutated clone: from stem cell to tumour.
    Leedham SJ; Wright NA
    J Clin Pathol; 2008 Feb; 61(2):164-71. PubMed ID: 17468295
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of adiponectin promotes intestinal carcinogenesis in Min and wild-type mice.
    Mutoh M; Teraoka N; Takasu S; Takahashi M; Onuma K; Yamamoto M; Kubota N; Iseki T; Kadowaki T; Sugimura T; Wakabayashi K
    Gastroenterology; 2011 Jun; 140(7):2000-8, 2008.e1-2. PubMed ID: 21334339
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TRIB3 Interacts With β-Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis.
    Hua F; Shang S; Yang YW; Zhang HZ; Xu TL; Yu JJ; Zhou DD; Cui B; Li K; Lv XX; Zhang XW; Liu SS; Yu JM; Wang F; Zhang C; Huang B; Hu ZW
    Gastroenterology; 2019 Feb; 156(3):708-721.e15. PubMed ID: 30365932
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.