These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 2967290)

  • 1. Transient inhibition of DNA synthesis by 5-fluorodeoxyuridine leads to overexpression of dihydrofolate reductase with increased frequency of methotrexate resistance.
    Schuetz JD; Gorse KM; Goldman ID; Westin EH
    J Biol Chem; 1988 Jun; 263(16):7708-12. PubMed ID: 2967290
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies.
    Jackman AL; Alison DL; Calvert AH; Harrap KR
    Cancer Res; 1986 Jun; 46(6):2810-5. PubMed ID: 2938731
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea.
    Brown PC; Tlsty TD; Schimke RT
    Mol Cell Biol; 1983 Jun; 3(6):1097-107. PubMed ID: 6877240
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate.
    Allegra CJ; Hoang K; Yeh GC; Drake JC; Baram J
    J Biol Chem; 1987 Oct; 262(28):13520-6. PubMed ID: 2443493
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potentiation of carcinogen-induced methotrexate resistance and dihydrofolate reductase gene amplification by inhibitors of poly(adenosine diphosphate-ribose) polymerase.
    Bürkle A; Heilbronn R; zur Hausen H
    Cancer Res; 1990 Sep; 50(18):5756-60. PubMed ID: 2118419
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for a functional defect in the translocation of the methotrexate transport carrier in a methotrexate-resistant murine L1210 leukemia cell line.
    Schuetz JD; Matherly LH; Westin EH; Goldman ID
    J Biol Chem; 1988 Jul; 263(20):9840-7. PubMed ID: 2838483
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Collateral sensitivity to azidothymidine in methotrexate resistant human leukemia cells.
    Miyachi H; Jiao L; Sowers LC; Scanlon KJ
    In Vivo; 1992; 6(1):17-21. PubMed ID: 1385729
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stimulation of dihydrofolate reductase promoter activity by antimetabolic drugs.
    Eastman HB; Swick AG; Schmitt MC; Azizkhan JC
    Proc Natl Acad Sci U S A; 1991 Oct; 88(19):8572-6. PubMed ID: 1833762
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stimulation of methotrexate resistance and dihydrofolate reductase gene amplification by c-myc.
    Denis N; Kitzis A; Kruh J; Dautry F; Corcos D
    Oncogene; 1991 Aug; 6(8):1453-7. PubMed ID: 1886715
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Establishment of dihydrofolate reductase-increased human cell lines and relationship between dihydrofolate reductase levels and gene copy.
    Domin BA; Grill SP; Cheng Y
    Cancer Res; 1983 May; 43(5):2155-8. PubMed ID: 6831441
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate.
    Assaraf YG; Molina A; Schimke RT
    J Biol Chem; 1989 Nov; 264(31):18326-34. PubMed ID: 2572592
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitogenic hormones and tumor promoters greatly increase the incidence of colony-forming cells bearing amplified dihydrofolate reductase genes.
    Barsoum J; Varshavsky A
    Proc Natl Acad Sci U S A; 1983 Sep; 80(17):5330-4. PubMed ID: 6351057
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective killing of methotrexate-resistant cells carrying amplified dihydrofolate reductase genes.
    Urlaub G; Landzberg M; Chasin LA
    Cancer Res; 1981 May; 41(5):1594-601. PubMed ID: 7194140
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A comparison of the propensity for gene amplification between near-tetraploid and near-diploid V79 clones resistant to 150 nM methotrexate.
    Hashimoto MW; Nikaido O; Kobayashi N; Chang CC; Trosko JE; Mori T
    Carcinogenesis; 1996 Mar; 17(3):389-94. PubMed ID: 8631121
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of thymidylate synthetase activity in development of methotrexate cytotoxicity.
    Moran RG; Mulkins M; Heidelberger C
    Proc Natl Acad Sci U S A; 1979 Nov; 76(11):5924-8. PubMed ID: 160558
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine.
    Zhang ZG; Malmberg M; Yin MB; Slocum HK; Rustum YM
    Biochem Pharmacol; 1993 Mar; 45(5):1157-64. PubMed ID: 8461045
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Further studies on the pharmacologic effects of the 7-hydroxy catabolite of methotrexate in the L1210 murine leukemia cell.
    Seither RL; Rape TJ; Goldman ID
    Biochem Pharmacol; 1989 Mar; 38(5):815-22. PubMed ID: 2467676
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transient inhibition of DNA synthesis results in increased dihydrofolate reductase synthesis and subsequent increased DNA content per cell.
    Johnston RN; Feder J; Hill AB; Sherwood SW; Schimke RT
    Mol Cell Biol; 1986 Oct; 6(10):3373-81. PubMed ID: 3099164
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Impaired drug uptake in methotrexate resistant Crithidia fasciculata without changes in dihydrofolate reductase activity or gene amplification.
    Dewes H; Ostergaard HL; Simpson L
    Mol Biochem Parasitol; 1986 May; 19(2):149-61. PubMed ID: 3724795
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells.
    Rice GC; Hoy C; Schimke RT
    Proc Natl Acad Sci U S A; 1986 Aug; 83(16):5978-82. PubMed ID: 3461470
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.