624 related articles for article (PubMed ID: 29677512)
1. Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.
Guo L; Kim HJ; Wang H; Monaghan J; Freyermuth F; Sung JC; O'Donovan K; Fare CM; Diaz Z; Singh N; Zhang ZC; Coughlin M; Sweeny EA; DeSantis ME; Jackrel ME; Rodell CB; Burdick JA; King OD; Gitler AD; Lagier-Tourenne C; Pandey UB; Chook YM; Taylor JP; Shorter J
Cell; 2018 Apr; 173(3):677-692.e20. PubMed ID: 29677512
[TBL] [Abstract][Full Text] [Related]
2. Therapeutic Dissolution of Aberrant Phases by Nuclear-Import Receptors.
Guo L; Fare CM; Shorter J
Trends Cell Biol; 2019 Apr; 29(4):308-322. PubMed ID: 30660504
[TBL] [Abstract][Full Text] [Related]
3. RNA-binding proteins with prion-like domains in health and disease.
Harrison AF; Shorter J
Biochem J; 2017 Apr; 474(8):1417-1438. PubMed ID: 28389532
[TBL] [Abstract][Full Text] [Related]
4. Nuclear-Import Receptors Counter Deleterious Phase Transitions in Neurodegenerative Disease.
Odeh HM; Fare CM; Shorter J
J Mol Biol; 2022 Jan; 434(1):167220. PubMed ID: 34464655
[TBL] [Abstract][Full Text] [Related]
5. Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Hofweber M; Hutten S; Bourgeois B; Spreitzer E; Niedner-Boblenz A; Schifferer M; Ruepp MD; Simons M; Niessing D; Madl T; Dormann D
Cell; 2018 Apr; 173(3):706-719.e13. PubMed ID: 29677514
[TBL] [Abstract][Full Text] [Related]
6. A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity.
Fare CM; Rhine K; Lam A; Myong S; Shorter J
J Biol Chem; 2023 Feb; 299(2):102806. PubMed ID: 36529289
[TBL] [Abstract][Full Text] [Related]
7. Nuclear-import receptors as gatekeepers of pathological phase transitions in ALS/FTD.
Khalil B; Linsenmeier M; Smith CL; Shorter J; Rossoll W
Mol Neurodegener; 2024 Jan; 19(1):8. PubMed ID: 38254150
[TBL] [Abstract][Full Text] [Related]
8. Identification and functional characterization of a novel nuclear localization signal present in the yeast Nab2 poly(A)+ RNA binding protein.
Truant R; Fridell RA; Benson RE; Bogerd H; Cullen BR
Mol Cell Biol; 1998 Mar; 18(3):1449-58. PubMed ID: 9488461
[TBL] [Abstract][Full Text] [Related]
9. Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease.
March ZM; King OD; Shorter J
Brain Res; 2016 Sep; 1647():9-18. PubMed ID: 26996412
[TBL] [Abstract][Full Text] [Related]
10. Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Yoshizawa T; Ali R; Jiou J; Fung HYJ; Burke KA; Kim SJ; Lin Y; Peeples WB; Saltzberg D; Soniat M; Baumhardt JM; Oldenbourg R; Sali A; Fawzi NL; Rosen MK; Chook YM
Cell; 2018 Apr; 173(3):693-705.e22. PubMed ID: 29677513
[TBL] [Abstract][Full Text] [Related]
11. De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies.
Mitsuhashi K; Ito D; Mashima K; Oyama M; Takahashi S; Suzuki N
Sci Rep; 2017 Dec; 7(1):16871. PubMed ID: 29203801
[TBL] [Abstract][Full Text] [Related]
12. The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors.
Baade I; Hutten S; Sternburg EL; Pörschke M; Hofweber M; Dormann D; Kehlenbach RH
J Biol Chem; 2021; 296():100659. PubMed ID: 33857479
[TBL] [Abstract][Full Text] [Related]
13. Biology and Pathobiology of TDP-43 and Emergent Therapeutic Strategies.
Guo L; Shorter J
Cold Spring Harb Perspect Med; 2017 Sep; 7(9):. PubMed ID: 27920024
[TBL] [Abstract][Full Text] [Related]
14. Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
Gonzalez A; Mannen T; Çağatay T; Fujiwara A; Matsumura H; Niesman AB; Brautigam CA; Chook YM; Yoshizawa T
Sci Rep; 2021 Feb; 11(1):3754. PubMed ID: 33580145
[TBL] [Abstract][Full Text] [Related]
15. Nuclear import factor transportin and arginine methyltransferase 1 modify FUS neurotoxicity in Drosophila.
Jäckel S; Summerer AK; Thömmes CM; Pan X; Voigt A; Schulz JB; Rasse TM; Dormann D; Haass C; Kahle PJ
Neurobiol Dis; 2015 Feb; 74():76-88. PubMed ID: 25447237
[TBL] [Abstract][Full Text] [Related]
16. Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.
Neumann M; Valori CF; Ansorge O; Kretzschmar HA; Munoz DG; Kusaka H; Yokota O; Ishihara K; Ang LC; Bilbao JM; Mackenzie IR
Acta Neuropathol; 2012 Nov; 124(5):705-16. PubMed ID: 22842875
[TBL] [Abstract][Full Text] [Related]
17. A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.
Gonzalez A; Kim HJ; Freibaum BD; Fung HYJ; Brautigam CA; Taylor JP; Chook YM
Structure; 2023 Aug; 31(8):924-934.e4. PubMed ID: 37279758
[TBL] [Abstract][Full Text] [Related]
18. Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains.
Guo L; Mann JR; Mauna JC; Copley KE; Wang H; Rubien JD; Odeh HM; Lin J; Lee BL; Ganser L; Robinson E; Kim KM; Murthy AC; Paul T; Portz B; Gleixner AM; Diaz Z; Carey JL; Smirnov A; Padilla G; Lavorando E; Espy C; Shang Y; Huang EJ; Chesi A; Fawzi NL; Myong S; Donnelly CJ; Shorter J
bioRxiv; 2023 Sep; ():. PubMed ID: 37732211
[TBL] [Abstract][Full Text] [Related]
19. Regulating Phase Transition in Neurodegenerative Diseases by Nuclear Import Receptors.
Girdhar A; Guo L
Biology (Basel); 2022 Jul; 11(7):. PubMed ID: 36101390
[TBL] [Abstract][Full Text] [Related]
20. C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers.
Nanaura H; Kawamukai H; Fujiwara A; Uehara T; Aiba Y; Nakanishi M; Shiota T; Hibino M; Wiriyasermkul P; Kikuchi S; Nagata R; Matsubayashi M; Shinkai Y; Niwa T; Mannen T; Morikawa N; Iguchi N; Kiriyama T; Morishima K; Inoue R; Sugiyama M; Oda T; Kodera N; Toma-Fukai S; Sato M; Taguchi H; Nagamori S; Shoji O; Ishimori K; Matsumura H; Sugie K; Saio T; Yoshizawa T; Mori E
Nat Commun; 2021 Sep; 12(1):5301. PubMed ID: 34489423
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]