BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 29678906)

  • 1. RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation.
    Oh RS; Haak AJ; Smith KMJ; Ligresti G; Choi KM; Xie T; Wang S; Walters PR; Thompson MA; Freeman MR; Manlove LJ; Chu VM; Feghali-Bostwick C; Roden AC; Schymeinsky J; Pabelick CM; Prakash YS; Vassallo R; Tschumperlin DJ
    J Cell Sci; 2018 May; 131(10):. PubMed ID: 29678906
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The JAK2 pathway is activated in idiopathic pulmonary fibrosis.
    Milara J; Hernandez G; Ballester B; Morell A; Roger I; Montero P; Escrivá J; Lloris JM; Molina-Molina M; Morcillo E; Cortijo J
    Respir Res; 2018 Feb; 19(1):24. PubMed ID: 29409529
    [TBL] [Abstract][Full Text] [Related]  

  • 3. STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation.
    Pedroza M; Le TT; Lewis K; Karmouty-Quintana H; To S; George AT; Blackburn MR; Tweardy DJ; Agarwal SK
    FASEB J; 2016 Jan; 30(1):129-40. PubMed ID: 26324850
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.
    Zhang Y; Dees C; Beyer C; Lin NY; Distler A; Zerr P; Palumbo K; Susok L; Kreuter A; Distler O; Schett G; Distler JH
    Ann Rheum Dis; 2015 May; 74(5):936-43. PubMed ID: 24431397
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of Rho-Associated Coiled-Coil Forming Kinase Isoforms in Regulation of Stiffness-Induced Myofibroblast Differentiation in Lung Fibrosis.
    Htwe SS; Cha BH; Yue K; Khademhosseini A; Knox AJ; Ghaemmaghami AM
    Am J Respir Cell Mol Biol; 2017 Jun; 56(6):772-783. PubMed ID: 28225294
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis.
    Chen H; Qu J; Huang X; Kurundkar A; Zhu L; Yang N; Venado A; Ding Q; Liu G; Antony VB; Thannickal VJ; Zhou Y
    Nat Commun; 2016 Aug; 7():12564. PubMed ID: 27535718
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tensin 1 Is Essential for Myofibroblast Differentiation and Extracellular Matrix Formation.
    Bernau K; Torr EE; Evans MD; Aoki JK; Ngam CR; Sandbo N
    Am J Respir Cell Mol Biol; 2017 Apr; 56(4):465-476. PubMed ID: 28005397
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis.
    Zhou Y; Huang X; Hecker L; Kurundkar D; Kurundkar A; Liu H; Jin TH; Desai L; Bernard K; Thannickal VJ
    J Clin Invest; 2013 Mar; 123(3):1096-108. PubMed ID: 23434591
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Featured Article: TGF-β1 dominates extracellular matrix rigidity for inducing differentiation of human cardiac fibroblasts to myofibroblasts.
    Cho N; Razipour SE; McCain ML
    Exp Biol Med (Maywood); 2018 Apr; 243(7):601-612. PubMed ID: 29504479
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sequential analysis of myofibroblast differentiation and transforming growth factor-β1/Smad pathway activation in murine pulmonary fibrosis.
    Usuki J; Matsuda K; Azuma A; Kudoh S; Gemma A
    J Nippon Med Sch; 2012; 79(1):46-59. PubMed ID: 22398790
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Noncanonical JAK1/STAT3 interactions with TGF-β modulate myofibroblast transdifferentiation and fibrosis.
    Wang F; Wang S; Zhang C; Tian X; Zhou Y; Xuan W; Matteson EL; Luo F; Tschumperlin D; Vassallo R
    Am J Physiol Lung Cell Mol Physiol; 2022 Dec; 323(6):L698-L714. PubMed ID: 36283961
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Piceatannol-mediated JAK2/STAT3 signaling pathway inhibition contributes to the alleviation of oxidative injury and collagen synthesis during pulmonary fibrosis.
    Tieyuan Z; Ying Z; Xinghua Z; Huimin W; Huagang L
    Int Immunopharmacol; 2022 Oct; 111():109107. PubMed ID: 35932616
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TGF-β-induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis.
    Dees C; Pötter S; Zhang Y; Bergmann C; Zhou X; Luber M; Wohlfahrt T; Karouzakis E; Ramming A; Gelse K; Yoshimura A; Jaenisch R; Distler O; Schett G; Distler JH
    J Clin Invest; 2020 May; 130(5):2347-2363. PubMed ID: 31990678
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis.
    Klein S; Rick J; Lehmann J; Schierwagen R; Schierwagen IG; Verbeke L; Hittatiya K; Uschner FE; Manekeller S; Strassburg CP; Wagner KU; Sayeski PP; Wolf D; Laleman W; Sauerbruch T; Trebicka J
    Gut; 2017 Jan; 66(1):145-155. PubMed ID: 26385087
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis.
    Hofmann K; Fiedler S; Vierkotten S; Weber J; Klee S; Jia J; Zwickenpflug W; Flockerzi V; Storch U; Yildirim AÖ; Gudermann T; Königshoff M; Dietrich A
    Biochim Biophys Acta Mol Basis Dis; 2017 Feb; 1863(2):560-568. PubMed ID: 27932059
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis.
    Molkentin JD; Bugg D; Ghearing N; Dorn LE; Kim P; Sargent MA; Gunaje J; Otsu K; Davis J
    Circulation; 2017 Aug; 136(6):549-561. PubMed ID: 28356446
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stemona alkaloids suppress the positive feedback loop between M2 polarization and fibroblast differentiation by inhibiting JAK2/STAT3 pathway in fibroblasts and CXCR4/PI
    Ding Q; Sun J; Xie W; Zhang M; Zhang C; Xu X
    Int Immunopharmacol; 2019 Jul; 72():385-394. PubMed ID: 31030094
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Purα/Purβ single-strand DNA-binding proteins attenuate smooth-muscle actin gene transactivation in myofibroblasts.
    Hariharan S; Kelm RJ; Strauch AR
    J Cell Physiol; 2014 Sep; 229(9):1256-71. PubMed ID: 24446247
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.
    Knipe RS; Probst CK; Lagares D; Franklin A; Spinney JJ; Brazee PL; Grasberger P; Zhang L; Black KE; Sakai N; Shea BS; Liao JK; Medoff BD; Tager AM
    Am J Respir Cell Mol Biol; 2018 Apr; 58(4):471-481. PubMed ID: 29211497
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy.
    Kurita Y; Araya J; Minagawa S; Hara H; Ichikawa A; Saito N; Kadota T; Tsubouchi K; Sato N; Yoshida M; Kobayashi K; Ito S; Fujita Y; Utsumi H; Yanagisawa H; Hashimoto M; Wakui H; Yoshii Y; Ishikawa T; Numata T; Kaneko Y; Asano H; Yamashita M; Odaka M; Morikawa T; Nakayama K; Kuwano K
    Respir Res; 2017 Jun; 18(1):114. PubMed ID: 28577568
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.