188 related articles for article (PubMed ID: 29681851)
1. DuCLOX-2/5 Inhibition Attenuates Inflammatory Response and Induces Mitochondrial Apoptosis for Mammary Gland Chemoprevention.
Gautam S; Rawat AK; Sammi SR; Roy S; Singh M; Devi U; Yadav RK; Singh L; Rawat JK; Ansari MN; Saeedan AS; Kumar D; Pandey R; Kaithwas G
Front Pharmacol; 2018; 9():314. PubMed ID: 29681851
[TBL] [Abstract][Full Text] [Related]
2. Effects of phenidone (DuCLOX-2/5 inhibitor) against N-methyl-N-nitrosourea induced mammary gland carcinoma in albino rats.
Gautam S; Rani S; Aldossary SA; Saeedan AS; Ansari MN; Kaithwas G
Toxicol Appl Pharmacol; 2018 Jul; 351():57-63. PubMed ID: 29679652
[TBL] [Abstract][Full Text] [Related]
3. Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling.
Singh M; Kasna S; Roy S; Aldosary S; Saeedan AS; Ansari MN; Kaithwas G
BMC Cancer; 2019 Oct; 19(1):996. PubMed ID: 31651285
[TBL] [Abstract][Full Text] [Related]
4. DuCLOX-2/5 inhibition: a promising target for cancer chemoprevention.
Gautam S; Roy S; Ansari MN; Saeedan AS; Saraf SA; Kaithwas G
Breast Cancer; 2017 Mar; 24(2):180-190. PubMed ID: 27558792
[TBL] [Abstract][Full Text] [Related]
5. Rifaximin, a pregnane X receptor (PXR) activator regulates apoptosis in a murine model of breast cancer.
Gautam S; Singh P; Singh M; Roy S; Rawat JK; Yadav RK; Devi U; Gupta PS; Saraf SA; Kaithwas G
RSC Adv; 2018 Jan; 8(7):3512-3521. PubMed ID: 35542911
[TBL] [Abstract][Full Text] [Related]
6. Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention.
Roy S; Rawat AK; Sammi SR; Devi U; Singh M; Gautam S; Yadav RK; Rawat JK; Singh L; Ansari MN; Saeedan AS; Pandey R; Kumar D; Kaithwas G
Oncotarget; 2017 Sep; 8(41):70049-70071. PubMed ID: 29050261
[TBL] [Abstract][Full Text] [Related]
7. α-Chymotrypsin regulates free fatty acids and UCHL-1 to ameliorate N-methyl nitrosourea induced mammary gland carcinoma in albino wistar rats.
Rani A; Roy S; Singh M; Devi U; Yadav RK; Gautam S; Rawat JK; Ansari MN; Saeedan AS; Prakash A; Kaithwas G
Inflammopharmacology; 2016 Oct; 24(5):277-286. PubMed ID: 27671329
[TBL] [Abstract][Full Text] [Related]
8. ALA-mediated biphasic downregulation of α-7nAchR/HIF-1α along with mitochondrial stress modulation strategy in mammary gland chemoprevention.
Roy S; Singh M; Sammi SR; Pandey R; Kaithwas G
J Cell Physiol; 2019 Apr; 234(4):4015-4029. PubMed ID: 30221357
[TBL] [Abstract][Full Text] [Related]
9. Chemoprophylactic activity of nitazoxanide in experimental model of mammary gland carcinoma in rats.
Pal AK; Nandave M; Kaithwas G
3 Biotech; 2020 Aug; 10(8):338. PubMed ID: 32670738
[TBL] [Abstract][Full Text] [Related]
10. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
El-Nagar MKS; Abdu-Allah HHM; Salem OIA; Kafafy AN; Farghaly HSM
Bioorg Chem; 2018 Aug; 78():80-93. PubMed ID: 29550533
[TBL] [Abstract][Full Text] [Related]
11. Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib.
Li N; Sood S; Wang S; Fang M; Wang P; Sun Z; Yang CS; Chen X
Clin Cancer Res; 2005 Mar; 11(5):2089-96. PubMed ID: 15756036
[TBL] [Abstract][Full Text] [Related]
12. 5-Lipoxygenase inhibitor zileuton inhibits neuronal apoptosis following focal cerebral ischemia.
Shi SS; Yang WZ; Tu XK; Wang CH; Chen CM; Chen Y
Inflammation; 2013 Dec; 36(6):1209-17. PubMed ID: 23695166
[TBL] [Abstract][Full Text] [Related]
13. Chemical activation of prolyl hydroxylase-2 by BBAP-1 down regulates hypoxia inducible factor-1α and fatty acid synthase for mammary gland chemoprevention.
Singh M; Devi U; Roy S; Gupta PS; Kaithwas G
RSC Adv; 2018 Apr; 8(23):12848-12860. PubMed ID: 35541235
[TBL] [Abstract][Full Text] [Related]
14. Zileuton alleviates acute cisplatin nephrotoxicity: Inhibition of lipoxygenase pathway favorably modulates the renal oxidative/inflammatory/caspase-3 axis.
Helmy MM; Hashim AA; Mouneir SM
Prostaglandins Other Lipid Mediat; 2018 Mar; 135():1-10. PubMed ID: 29355720
[TBL] [Abstract][Full Text] [Related]
15. Activation of prolyl hydroxylase-2 for stabilization of mitochondrial stress along with simultaneous downregulation of HIF-1α/FASN in ER + breast cancer subtype.
Devi U; Singh M; Roy S; Gupta PS; Ansari MN; Saeedan AS; Kaithwas G
Cell Biochem Funct; 2019 Jun; 37(4):216-227. PubMed ID: 30950543
[TBL] [Abstract][Full Text] [Related]
16. Novel di-tertiary-butyl phenylhydrazones as dual cyclooxygenase-2/5-lipoxygenase inhibitors: synthesis, COX/LOX inhibition, molecular modeling, and insights into their cytotoxicities.
Ghatak S; Vyas A; Misra S; O'Brien P; Zambre A; Fresco VM; Markwald RR; Swamy KV; Afrasiabi Z; Choudhury A; Khetmalas M; Padhye S
Bioorg Med Chem Lett; 2014 Jan; 24(1):317-24. PubMed ID: 24295787
[TBL] [Abstract][Full Text] [Related]
17. Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.
Tavolari S; Bonafè M; Marini M; Ferreri C; Bartolini G; Brighenti E; Manara S; Tomasi V; Laufer S; Guarnieri T
Carcinogenesis; 2008 Feb; 29(2):371-80. PubMed ID: 18033773
[TBL] [Abstract][Full Text] [Related]
18. Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis.
Chen X; Wang S; Wu N; Sood S; Wang P; Jin Z; Beer DG; Giordano TJ; Lin Y; Shih WC; Lubet RA; Yang CS
Clin Cancer Res; 2004 Oct; 10(19):6703-9. PubMed ID: 15475461
[TBL] [Abstract][Full Text] [Related]
19. Mitochondrial apoptosis and curtailment of hypoxia-inducible factor-1α/fatty acid synthase: A dual edge perspective of gamma linolenic acid in ER+ mammary gland cancer.
Roy S; Singh M; Rawat A; Kumar D; Kaithwas G
Cell Biochem Funct; 2020 Jul; 38(5):591-603. PubMed ID: 32207176
[TBL] [Abstract][Full Text] [Related]
20. QbD-based development of α-linolenic acid potentiated nanoemulsion for targeted delivery of doxorubicin in DMBA-induced mammary gland carcinoma: in vitro and in vivo evaluation.
Tripathi CB; Parashar P; Arya M; Singh M; Kanoujia J; Kaithwas G; Saraf SA
Drug Deliv Transl Res; 2018 Oct; 8(5):1313-1334. PubMed ID: 29748834
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]