BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 29684376)

  • 1. Angiotensin II cyclic analogs as tools to investigate AT
    St-Pierre D; Cabana J; Holleran BJ; Besserer-Offroy É; Escher E; Guillemette G; Lavigne P; Leduc R
    Biochem Pharmacol; 2018 Aug; 154():104-117. PubMed ID: 29684376
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
    Wingler LM; Skiba MA; McMahon C; Staus DP; Kleinhenz ALW; Suomivuori CM; Latorraca NR; Dror RO; Lefkowitz RJ; Kruse AC
    Science; 2020 Feb; 367(6480):888-892. PubMed ID: 32079768
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Label-free cell signaling pathway deconvolution of angiotensin type 1 receptor reveals time-resolved G-protein activity and distinct AngII and AngIIIIV responses.
    Lavenus S; Simard É; Besserer-Offroy É; Froehlich U; Leduc R; Grandbois M
    Pharmacol Res; 2018 Oct; 136():108-120. PubMed ID: 29959993
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simulations.
    Cabana J; Holleran B; Leduc R; Escher E; Guillemette G; Lavigne P
    J Biol Chem; 2015 Jun; 290(25):15835-15854. PubMed ID: 25934394
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biased agonism of the angiotensin II type 1 receptor.
    Godin CM; Ferguson SS
    Mini Rev Med Chem; 2012 Aug; 12(9):812-6. PubMed ID: 22681254
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of biased signaling at a G protein-coupled receptor in overexpressed systems.
    Li A; Liu S; Huang R; Ahn S; Lefkowitz RJ
    PLoS One; 2023; 18(3):e0283477. PubMed ID: 36961836
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch.
    Tang W; Strachan RT; Lefkowitz RJ; Rockman HA
    J Biol Chem; 2014 Oct; 289(41):28271-83. PubMed ID: 25170081
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adrenal angiotensin II type 1 receptor biased signaling: The case for "biased" inverse agonism for effective aldosterone suppression.
    Ferraino KE; Cora N; Pollard CM; Sizova A; Maning J; Lymperopoulos A
    Cell Signal; 2021 Jun; 82():109967. PubMed ID: 33640432
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity.
    Domazet I; Holleran BJ; Richard A; Vandenberghe C; Lavigne P; Escher E; Leduc R; Guillemette G
    Mol Pharmacol; 2015 Jun; 87(6):982-95. PubMed ID: 25808928
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Single-molecule force spectroscopy study of interactions between angiotensin II type 1 receptor and different biased ligands in living cells.
    Li W; Xu J; Kou X; Zhao R; Zhou W; Fang X
    Anal Bioanal Chem; 2018 May; 410(14):3275-3284. PubMed ID: 29492619
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers.
    Wilson PC; Lee MH; Appleton KM; El-Shewy HM; Morinelli TA; Peterson YK; Luttrell LM; Jaffa AA
    J Biol Chem; 2013 Jun; 288(26):18872-84. PubMed ID: 23661707
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Quantifying biased signaling in GPCRs using BRET-based biosensors.
    Namkung Y; Radresa O; Armando S; Devost D; Beautrait A; Le Gouill C; Laporte SA
    Methods; 2016 Jan; 92():5-10. PubMed ID: 25890247
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs.
    Zimmerman B; Beautrait A; Aguila B; Charles R; Escher E; Claing A; Bouvier M; Laporte SA
    Sci Signal; 2012 Apr; 5(221):ra33. PubMed ID: 22534132
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody.
    Wingler LM; McMahon C; Staus DP; Lefkowitz RJ; Kruse AC
    Cell; 2019 Jan; 176(3):479-490.e12. PubMed ID: 30639100
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Current topics in angiotensin II type 1 receptor research: Focus on inverse agonism, receptor dimerization and biased agonism.
    Takezako T; Unal H; Karnik SS; Node K
    Pharmacol Res; 2017 Sep; 123():40-50. PubMed ID: 28648738
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biased agonists differentially modulate the receptor conformation ensembles in Angiotensin II type 1 receptor.
    Nivedha AK; Lee S; Vaidehi N
    J Mol Graph Model; 2023 Jan; 118():108365. PubMed ID: 36335829
    [TBL] [Abstract][Full Text] [Related]  

  • 17. β-Arrestin-biased AT1R stimulation promotes extracellular matrix synthesis in renal fibrosis.
    Wang Y; Huang J; Liu X; Niu Y; Zhao L; Yu Y; Zhou L; Lu L; Yu C
    Am J Physiol Renal Physiol; 2017 Jul; 313(1):F1-F8. PubMed ID: 28274926
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors.
    Namkung Y; LeGouill C; Kumar S; Cao Y; Teixeira LB; Lukasheva V; Giubilaro J; Simões SC; Longpré JM; Devost D; Hébert TE; Piñeyro G; Leduc R; Costa-Neto CM; Bouvier M; Laporte SA
    Sci Signal; 2018 Dec; 11(559):. PubMed ID: 30514808
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biased Agonism of the Angiotensin II Type I Receptor.
    Ikeda Y; Kumagai H; Motozawa Y; Suzuki J; Komuro I
    Int Heart J; 2015; 56(5):485-8. PubMed ID: 26180022
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cardiovascular angiotensin II type 1 receptor biased signaling: Focus on non-Gq-, non-βarrestin-dependent signaling.
    Lymperopoulos A; Borges JI; Carbone AM; Cora N; Sizova A
    Pharmacol Res; 2021 Dec; 174():105943. PubMed ID: 34662735
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.