346 related articles for article (PubMed ID: 29686315)
1. Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β.
Arndt JW; Qian F; Smith BA; Quan C; Kilambi KP; Bush MW; Walz T; Pepinsky RB; Bussière T; Hamann S; Cameron TO; Weinreb PH
Sci Rep; 2018 Apr; 8(1):6412. PubMed ID: 29686315
[TBL] [Abstract][Full Text] [Related]
2. From monomer to fibril: Abeta-amyloid binding to Aducanumab antibody studied by molecular dynamics simulation.
Frost CV; Zacharias M
Proteins; 2020 Dec; 88(12):1592-1606. PubMed ID: 32666627
[TBL] [Abstract][Full Text] [Related]
3. Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies.
Linse S; Scheidt T; Bernfur K; Vendruscolo M; Dobson CM; Cohen SIA; Sileikis E; Lundqvist M; Qian F; O'Malley T; Bussiere T; Weinreb PH; Xu CK; Meisl G; Devenish SRA; Knowles TPJ; Hansson O
Nat Struct Mol Biol; 2020 Dec; 27(12):1125-1133. PubMed ID: 32989305
[TBL] [Abstract][Full Text] [Related]
4. Molecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies.
Crespi GA; Hermans SJ; Parker MW; Miles LA
Sci Rep; 2015 Apr; 5():9649. PubMed ID: 25880481
[TBL] [Abstract][Full Text] [Related]
5. Mechanisms of recognition of amyloid-β (Aβ) monomer, oligomer, and fibril by homologous antibodies.
Zhao J; Nussinov R; Ma B
J Biol Chem; 2017 Nov; 292(44):18325-18343. PubMed ID: 28924036
[TBL] [Abstract][Full Text] [Related]
6. Humoral immune response to fibrillar beta-amyloid peptide.
Miller DL; Currie JR; Mehta PD; Potempska A; Hwang YW; Wegiel J
Biochemistry; 2003 Oct; 42(40):11682-92. PubMed ID: 14529278
[TBL] [Abstract][Full Text] [Related]
7. Gantenerumab: a novel human anti-Aβ antibody demonstrates sustained cerebral amyloid-β binding and elicits cell-mediated removal of human amyloid-β.
Bohrmann B; Baumann K; Benz J; Gerber F; Huber W; Knoflach F; Messer J; Oroszlan K; Rauchenberger R; Richter WF; Rothe C; Urban M; Bardroff M; Winter M; Nordstedt C; Loetscher H
J Alzheimers Dis; 2012; 28(1):49-69. PubMed ID: 21955818
[TBL] [Abstract][Full Text] [Related]
8. Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation.
Miles LA; Crespi GA; Doughty L; Parker MW
Sci Rep; 2013; 3():1302. PubMed ID: 23416764
[TBL] [Abstract][Full Text] [Related]
9. Clinical Development of Aducanumab, an Anti-Aβ Human Monoclonal Antibody Being Investigated for the Treatment of Early Alzheimer's Disease.
Budd Haeberlein S; O'Gorman J; Chiao P; Bussière T; von Rosenstiel P; Tian Y; Zhu Y; von Hehn C; Gheuens S; Skordos L; Chen T; Sandrock A
J Prev Alzheimers Dis; 2017; 4(4):255-263. PubMed ID: 29181491
[TBL] [Abstract][Full Text] [Related]
10. Immunotherapy with Aducanumab Restores Calcium Homeostasis in Tg2576 Mice.
Kastanenka KV; Bussiere T; Shakerdge N; Qian F; Weinreb PH; Rhodes K; Bacskai BJ
J Neurosci; 2016 Dec; 36(50):12549-12558. PubMed ID: 27810931
[TBL] [Abstract][Full Text] [Related]
11. SAR228810: an antibody for protofibrillar amyloid β peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA).
Pradier L; Blanchard-Brégeon V; Bohme A; Debeir T; Menager J; Benoit P; Barneoud P; Taupin V; Bertrand P; Dugay P; Cameron B; Shi Y; Naimi S; Duchesne M; Gagnaire M; Weeden T; Travaline T; Reczek D; Khiroug L; Slaoui M; Brunel P; Fukuyama H; Ravetch J; Canton T; Cohen C
Alzheimers Res Ther; 2018 Nov; 10(1):117. PubMed ID: 30486882
[TBL] [Abstract][Full Text] [Related]
12. Molecular basis for passive immunotherapy of Alzheimer's disease.
Gardberg AS; Dice LT; Ou S; Rich RL; Helmbrecht E; Ko J; Wetzel R; Myszka DG; Patterson PH; Dealwis C
Proc Natl Acad Sci U S A; 2007 Oct; 104(40):15659-64. PubMed ID: 17895381
[TBL] [Abstract][Full Text] [Related]
13. Amyloid-beta antibody binding to cerebral amyloid angiopathy fibrils and risk for amyloid-related imaging abnormalities.
Söderberg L; Johannesson M; Gkanatsiou E; Nygren P; Fritz N; Zachrisson O; Rachalski A; Svensson AS; Button E; Dentoni G; Osswald G; Lannfelt L; Möller C
Sci Rep; 2024 May; 14(1):10868. PubMed ID: 38740836
[TBL] [Abstract][Full Text] [Related]
14. Are antibodies directed against amyloid-β (Aβ) oligomers the last call for the Aβ hypothesis of Alzheimer's disease?
Panza F; Lozupone M; Dibello V; Greco A; Daniele A; Seripa D; Logroscino G; Imbimbo BP
Immunotherapy; 2019 Jan; 11(1):3-6. PubMed ID: 30702009
[No Abstract] [Full Text] [Related]
15. Passive immunotherapy for Alzheimer's disease: challenges & future directions.
Yi LX; Tan EK; Zhou ZD
J Transl Med; 2024 May; 22(1):430. PubMed ID: 38715084
[TBL] [Abstract][Full Text] [Related]
16. Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N‑truncated Abeta in sporadic Alzheimer disease cases and mouse models.
Bouter Y; Lopez Noguerola JS; Tucholla P; Crespi GA; Parker MW; Wiltfang J; Miles LA; Bayer TA
Acta Neuropathol; 2015 Nov; 130(5):713-29. PubMed ID: 26467270
[TBL] [Abstract][Full Text] [Related]
17. Computational Investigation of Gantenerumab and Crenezumab Recognition of Aβ Fibrils in Alzheimer's Disease Brain Tissue.
Chen Y; Wei G; Zhao J; Nussinov R; Ma B
ACS Chem Neurosci; 2020 Oct; 11(20):3233-3244. PubMed ID: 32991803
[TBL] [Abstract][Full Text] [Related]
18. Native ion mobility-mass spectrometry reveals the binding mechanisms of anti-amyloid therapeutic antibodies.
Han Y; Desai AA; Zupancic JM; Smith MD; Tessier PM; Ruotolo BT
Protein Sci; 2024 Jun; 33(6):e5008. PubMed ID: 38723181
[TBL] [Abstract][Full Text] [Related]
19. Amyloid-directed monoclonal antibodies for the treatment of Alzheimer's disease: the point of no return?
Panza F; Solfrizzi V; Imbimbo BP; Logroscino G
Expert Opin Biol Ther; 2014 Oct; 14(10):1465-76. PubMed ID: 24981190
[TBL] [Abstract][Full Text] [Related]
20. Aducanumab, gantenerumab, BAN2401, and ALZ-801-the first wave of amyloid-targeting drugs for Alzheimer's disease with potential for near term approval.
Tolar M; Abushakra S; Hey JA; Porsteinsson A; Sabbagh M
Alzheimers Res Ther; 2020 Aug; 12(1):95. PubMed ID: 32787971
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]