267 related articles for article (PubMed ID: 29688812)
1. Nitration of microtubules blocks axonal mitochondrial transport in a human pluripotent stem cell model of Parkinson's disease.
Stykel MG; Humphries K; Kirby MP; Czaniecki C; Wang T; Ryan T; Bamm V; Ryan SD
FASEB J; 2018 Oct; 32(10):5350-5364. PubMed ID: 29688812
[TBL] [Abstract][Full Text] [Related]
2. Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription.
Ryan SD; Dolatabadi N; Chan SF; Zhang X; Akhtar MW; Parker J; Soldner F; Sunico CR; Nagar S; Talantova M; Lee B; Lopez K; Nutter A; Shan B; Molokanova E; Zhang Y; Han X; Nakamura T; Masliah E; Yates JR; Nakanishi N; Andreyev AY; Okamoto S; Jaenisch R; Ambasudhan R; Lipton SA
Cell; 2013 Dec; 155(6):1351-64. PubMed ID: 24290359
[TBL] [Abstract][Full Text] [Related]
3. α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies.
Prots I; Grosch J; Brazdis RM; Simmnacher K; Veber V; Havlicek S; Hannappel C; Krach F; Krumbiegel M; Schütz O; Reis A; Wrasidlo W; Galasko DR; Groemer TW; Masliah E; Schlötzer-Schrehardt U; Xiang W; Winkler J; Winner B
Proc Natl Acad Sci U S A; 2018 Jul; 115(30):7813-7818. PubMed ID: 29991596
[TBL] [Abstract][Full Text] [Related]
4. Axonal pathology in hPSC-based models of Parkinson's disease results from loss of Nrf2 transcriptional activity at the Map1b gene locus.
Czaniecki C; Ryan T; Stykel MG; Drolet J; Heide J; Hallam R; Wood S; Coackley C; Sherriff K; Bailey CDC; Ryan SD
Proc Natl Acad Sci U S A; 2019 Jul; 116(28):14280-14289. PubMed ID: 31235589
[TBL] [Abstract][Full Text] [Related]
5. Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease.
Kouroupi G; Taoufik E; Vlachos IS; Tsioras K; Antoniou N; Papastefanaki F; Chroni-Tzartou D; Wrasidlo W; Bohl D; Stellas D; Politis PK; Vekrellis K; Papadimitriou D; Stefanis L; Bregestovski P; Hatzigeorgiou AG; Masliah E; Matsas R
Proc Natl Acad Sci U S A; 2017 May; 114(18):E3679-E3688. PubMed ID: 28416701
[TBL] [Abstract][Full Text] [Related]
6. Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Familial Parkinson's Disease Patients Display α-Synuclein Pathology and Abnormal Mitochondrial Morphology.
Diao X; Wang F; Becerra-Calixto A; Soto C; Mukherjee A
Cells; 2021 Sep; 10(9):. PubMed ID: 34572052
[TBL] [Abstract][Full Text] [Related]
7. Generation of gene-corrected iPSC line from Parkinson's disease patient iPSC line with alpha-SNCA A53T mutation.
Lee SY; Jeong S; Kim J; Chung SK
Stem Cell Res; 2018 Jul; 30():145-149. PubMed ID: 29906669
[TBL] [Abstract][Full Text] [Related]
8. Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse.
Perfeito R; Cunha-Oliveira T; Rego AC
Free Radic Biol Med; 2013 Sep; 62():186-201. PubMed ID: 23743292
[TBL] [Abstract][Full Text] [Related]
9. Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.
Flierl A; Oliveira LM; Falomir-Lockhart LJ; Mak SK; Hesley J; Soldner F; Arndt-Jovin DJ; Jaenisch R; Langston JW; Jovin TM; Schüle B
PLoS One; 2014; 9(11):e112413. PubMed ID: 25390032
[TBL] [Abstract][Full Text] [Related]
10. Involvement of mortalin/GRP75/mthsp70 in the mitochondrial impairments induced by A53T mutant α-synuclein.
Liu FT; Chen Y; Yang YJ; Yang L; Yu M; Zhao J; Wu JJ; Huang F; Liu W; Ding ZT; Wang J
Brain Res; 2015 Apr; 1604():52-61. PubMed ID: 25665531
[TBL] [Abstract][Full Text] [Related]
11. Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production.
Tapias V; Hu X; Luk KC; Sanders LH; Lee VM; Greenamyre JT
Cell Mol Life Sci; 2017 Aug; 74(15):2851-2874. PubMed ID: 28534083
[TBL] [Abstract][Full Text] [Related]
12. Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.
Martin LJ; Pan Y; Price AC; Sterling W; Copeland NG; Jenkins NA; Price DL; Lee MK
J Neurosci; 2006 Jan; 26(1):41-50. PubMed ID: 16399671
[TBL] [Abstract][Full Text] [Related]
13. Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein.
Ryan T; Bamm VV; Stykel MG; Coackley CL; Humphries KM; Jamieson-Williams R; Ambasudhan R; Mosser DD; Lipton SA; Harauz G; Ryan SD
Nat Commun; 2018 Feb; 9(1):817. PubMed ID: 29483518
[TBL] [Abstract][Full Text] [Related]
14. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Hu D; Sun X; Liao X; Zhang X; Zarabi S; Schimmer A; Hong Y; Ford C; Luo Y; Qi X
Acta Neuropathol; 2019 Jun; 137(6):939-960. PubMed ID: 30877431
[TBL] [Abstract][Full Text] [Related]
15. Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain.
Devi L; Raghavendran V; Prabhu BM; Avadhani NG; Anandatheerthavarada HK
J Biol Chem; 2008 Apr; 283(14):9089-100. PubMed ID: 18245082
[TBL] [Abstract][Full Text] [Related]
16. Interaction of Alpha Synuclein and Microtubule Organization Is Linked to Impaired Neuritic Integrity in Parkinson's Patient-Derived Neuronal Cells.
Seebauer L; Schneider Y; Drobny A; Plötz S; Koudelka T; Tholey A; Prots I; Winner B; Zunke F; Winkler J; Xiang W
Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163733
[TBL] [Abstract][Full Text] [Related]
17. A split-GFP tool reveals differences in the sub-mitochondrial distribution of wt and mutant alpha-synuclein.
Vicario M; Cieri D; Vallese F; Catoni C; Barazzuol L; Berto P; Grinzato A; Barbieri L; Brini M; Calì T
Cell Death Dis; 2019 Nov; 10(11):857. PubMed ID: 31719530
[TBL] [Abstract][Full Text] [Related]
18. Mesenchymal Stem Cells Stabilize Axonal Transports for Autophagic Clearance of α-Synuclein in Parkinsonian Models.
Oh SH; Lee SC; Kim DY; Kim HN; Shin JY; Ye BS; Lee PH
Stem Cells; 2017 Aug; 35(8):1934-1947. PubMed ID: 28580639
[TBL] [Abstract][Full Text] [Related]
19. Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
Fukusumi H; Togo K; Sumida M; Nakamori M; Obika S; Baba K; Shofuda T; Ito D; Okano H; Mochizuki H; Kanemura Y
FEBS Open Bio; 2021 Feb; 11(2):354-366. PubMed ID: 33301617
[TBL] [Abstract][Full Text] [Related]
20. The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease.
Zuo L; Motherwell MS
Gene; 2013 Dec; 532(1):18-23. PubMed ID: 23954870
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
