119 related articles for article (PubMed ID: 29692266)
1. Insights into the Biological Evaluation of Pterocarpanquinones and Carbapterocarpans with Anti-tumor Activity against MDR Leukemias.
Rumjanek VM; Maia RC; Salustiano EJ; Costa PRR
Anticancer Agents Med Chem; 2019; 19(1):29-37. PubMed ID: 29692266
[TBL] [Abstract][Full Text] [Related]
2. The therapeutical potential of a novel pterocarpanquinone LQB-118 to target inhibitor of apoptosis proteins in acute myeloid leukemia cells.
de Souza Reis FR; de Faria FC; Castro CP; de Souza PS; da Cunha Vasconcelos F; Bello RD; da Silva AJ; Costa PR; Maia RC
Anticancer Agents Med Chem; 2013 Feb; 13(2):341-51. PubMed ID: 22721384
[TBL] [Abstract][Full Text] [Related]
3. 11a-N-Tosyl-5-deoxi-pterocarpan (LQB-223), a promising prototype for targeting MDR leukemia cell lines.
Buarque CD; Salustiano EJ; Fraga KC; Alves BR; Costa PR
Eur J Med Chem; 2014 May; 78():190-7. PubMed ID: 24681983
[TBL] [Abstract][Full Text] [Related]
4. The pterocarpanquinone LQB 118 induces apoptosis in tumor cells through the intrinsic pathway and the endoplasmic reticulum stress pathway.
de Sá Bacelar T; da Silva AJ; Costa PR; Rumjanek VM
Anticancer Drugs; 2013 Jan; 24(1):73-83. PubMed ID: 22960938
[TBL] [Abstract][Full Text] [Related]
5. LQB-118, a pterocarpanquinone structurally related to lapachol [2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone]: a novel class of agent with high apoptotic effect in chronic myeloid leukemia cells.
Maia RC; Vasconcelos FC; de Sá Bacelar T; Salustiano EJ; da Silva LF; Pereira DL; Moellman-Coelho A; Netto CD; da Silva AJ; Rumjanek VM; Costa PR
Invest New Drugs; 2011 Dec; 29(6):1143-55. PubMed ID: 20499132
[TBL] [Abstract][Full Text] [Related]
6. The LQB-223 Compound Modulates Antiapoptotic Proteins and Impairs Breast Cancer Cell Growth and Migration.
Lemos LGT; Longo GMDC; Mendonça BDS; Robaina MC; Brum MCM; Cirilo CA; Gimba ERP; Costa PRR; Buarque CD; Nestal de Moraes G; Maia RC
Int J Mol Sci; 2019 Oct; 20(20):. PubMed ID: 31614718
[TBL] [Abstract][Full Text] [Related]
7. The orally active pterocarpanquinone LQB-118 exhibits cytotoxicity in prostate cancer cell and tumor models through cellular redox stress.
Martino T; Kudrolli TA; Kumar B; Salviano I; Mencalha A; Coelho MGP; Justo G; Costa PRR; Sabino KCC; Lupold SE
Prostate; 2018 Feb; 78(2):140-151. PubMed ID: 29105806
[TBL] [Abstract][Full Text] [Related]
8. 11a-N-tosyl-5-carbapterocarpans: Synthesis, antineoplastic evaluation and in silico prediction of ADMETox properties.
Mendes JA; Salustiano EJ; Pires CS; Oliveira T; Barcellos JCF; Cifuentes JMC; Costa PRR; Rennó MN; Buarque CD
Bioorg Chem; 2018 Oct; 80():585-590. PubMed ID: 30036814
[TBL] [Abstract][Full Text] [Related]
9. Pterocarpanquinones, aza-pterocarpanquinone and derivatives: synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis.
Buarque CD; Militão GC; Lima DJ; Costa-Lotufo LV; Pessoa C; de Moraes MO; Cunha-Junior EF; Torres-Santos EC; Netto CD; Costa PR
Bioorg Med Chem; 2011 Nov; 19(22):6885-91. PubMed ID: 22000949
[TBL] [Abstract][Full Text] [Related]
10. 11a-N-Tosyl-5-deoxi-pterocarpan, LQB-223, a novel compound with potent antineoplastic activity toward breast cancer cells with different phenotypes.
Lemos LG; Nestal de Moraes G; Delbue D; Vasconcelos Fda C; Bernardo PS; Lam EW; Buarque CD; Costa PR; Maia RC
J Cancer Res Clin Oncol; 2016 Oct; 142(10):2119-30. PubMed ID: 27520309
[TBL] [Abstract][Full Text] [Related]
11. The pterocarpanquinone LQB-118 induces apoptosis in acute myeloid leukemia cells of distinct molecular subtypes and targets FoxO3a and FoxM1 transcription factors.
Nestal de Moraes G; Castro CP; Salustiano EJ; Dumas ML; Costas F; Lam EW; Costa PR; Maia RC
Int J Oncol; 2014 Nov; 45(5):1949-58. PubMed ID: 25174716
[TBL] [Abstract][Full Text] [Related]
12. In vitro and in vivo antineoplastic and immunological effects of pterocarpanquinone LQB-118.
Salustiano EJ; Dumas ML; Silva-Santos GG; Netto CD; Costa PR; Rumjanek VM
Invest New Drugs; 2016 Oct; 34(5):541-51. PubMed ID: 27189479
[TBL] [Abstract][Full Text] [Related]
13. NFκB pathway and microRNA-9 and -21 are involved in sensitivity to the pterocarpanquinone LQB-118 in different CML cell lines.
de Faria FC; Leal ME; Bernardo PS; Costa PR; Maia RC
Anticancer Agents Med Chem; 2015; 15(3):345-52. PubMed ID: 25964959
[TBL] [Abstract][Full Text] [Related]
14. The pterocarpanquinone LQB-118 inhibits tumor cell proliferation by downregulation of c-Myc and cyclins D1 and B1 mRNA and upregulation of p21 cell cycle inhibitor expression.
Martino T; Magalhães FC; Justo GA; Coelho MG; Netto CD; Costa PR; Sabino KC
Bioorg Med Chem; 2014 Jun; 22(12):3115-22. PubMed ID: 24794748
[TBL] [Abstract][Full Text] [Related]
15. Anti-inflammatory properties of pterocarpanquinone LQB-118 in mice.
Riça IG; Netto CD; Rennó MN; Abreu PA; Costa PRR; da Silva AJM; Cavalcante MCM
Bioorg Med Chem; 2016 Sep; 24(18):4415-4423. PubMed ID: 27492193
[TBL] [Abstract][Full Text] [Related]
16. Medicarpin and millepurpan, two flavonoids isolated from Medicago sativa, induce apoptosis and overcome multidrug resistance in leukemia P388 cells.
Gatouillat G; Magid AA; Bertin E; El btaouri H; Morjani H; Lavaud C; Madoulet C
Phytomedicine; 2015 Dec; 22(13):1186-94. PubMed ID: 26598918
[TBL] [Abstract][Full Text] [Related]
17. A newly synthesized nickel chelate can selectively target and overcome multidrug resistance in cancer through redox imbalance both in vivo and in vitro.
Banerjee K; Biswas MK; Choudhuri SK
J Biol Inorg Chem; 2017 Dec; 22(8):1223-1249. PubMed ID: 29063196
[TBL] [Abstract][Full Text] [Related]
18. New pterocarpanquinones: synthesis, antineoplasic activity on cultured human malignant cell lines and TNF-alpha modulation in human PBMC cells.
Netto CD; da Silva AJ; Salustiano EJ; Bacelar TS; Riça IG; Cavalcante MC; Rumjanek VM; Costa PR
Bioorg Med Chem; 2010 Feb; 18(4):1610-6. PubMed ID: 20117936
[TBL] [Abstract][Full Text] [Related]
19. LQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis.
Ribeiro GA; Cunha-Júnior EF; Pinheiro RO; da-Silva SA; Canto-Cavalheiro MM; da Silva AJ; Costa PR; Netto CD; Melo RC; Almeida-Amaral EE; Torres-Santos EC
J Antimicrob Chemother; 2013 Apr; 68(4):789-99. PubMed ID: 23288404
[TBL] [Abstract][Full Text] [Related]
20. H1, a derivative of Tetrandrine, exerts anti-MDR activity by initiating intrinsic apoptosis pathway and inhibiting the activation of Erk1/2 and Akt1/2.
Wei N; Liu GT; Chen XG; Liu Q; Wang FP; Sun H
Biochem Pharmacol; 2011 Dec; 82(11):1593-603. PubMed ID: 21864508
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
