233 related articles for article (PubMed ID: 29697032)
1. Synthesis, 17α-hydroxylase-C
Banday AH; Shameem SA; Banday JA; Ganaie BA
Anticancer Agents Med Chem; 2018; 18(13):1919-1926. PubMed ID: 29697032
[TBL] [Abstract][Full Text] [Related]
2. Steroidal pyrazolines and pyrazoles as potential 5α-reductase inhibitors: synthesis and biological evaluation.
Banday AH; Shameem SA; Jeelani S
Steroids; 2014 Dec; 92():13-9. PubMed ID: 25278254
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and evaluation of novel steroidal oxime inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase) and 5 alpha-reductase types 1 and 2.
Hartmann RW; Hector M; Haidar S; Ehmer PB; Reichert W; Jose J
J Med Chem; 2000 Nov; 43(22):4266-77. PubMed ID: 11063622
[TBL] [Abstract][Full Text] [Related]
4. C16 and C17 substituted derivatives of pregnenolone and progesterone as inhibitors of 17alpha-hydroxylase-C17, 20-lyase: synthesis and biological evaluation.
Haidar S; Hartmann RW
Arch Pharm (Weinheim); 2002; 335(11-12):526-34. PubMed ID: 12596217
[TBL] [Abstract][Full Text] [Related]
5. Steroidal Oximes: Useful Compounds with Antitumor Activities.
Canario C; Silvestre S; Falcao A; Alves G
Curr Med Chem; 2018 Feb; 25(6):660-686. PubMed ID: 28971759
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and evaluation of 17-aliphatic heterocycle-substituted steroidal inhibitors of 17alpha-hydroxylase/C17-20-lyase (P450 17).
Hartmann RW; Hector M; Wachall BG; Palusczak A; Palzer M; Huch V; Veith M
J Med Chem; 2000 Nov; 43(23):4437-45. PubMed ID: 11087568
[TBL] [Abstract][Full Text] [Related]
7. An efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17α-hydroxylase/C₁₇,₂₀-lyase.
Kovács D; Wölfling J; Szabó N; Szécsi M; Kovács I; Zupkó I; Frank E
Eur J Med Chem; 2013; 70():649-60. PubMed ID: 24211641
[TBL] [Abstract][Full Text] [Related]
8. Effects of some novel inhibitors of C17,20-lyase and 5alpha-reductase in vitro and in vivo and their potential role in the treatment of prostate cancer.
Nnane IP; Kato K; Liu Y; Lu Q; Wang X; Ling YZ; Brodie A
Cancer Res; 1998 Sep; 58(17):3826-32. PubMed ID: 9731491
[TBL] [Abstract][Full Text] [Related]
9. Growth inhibition of human prostate cells in vitro by novel inhibitors of androgen synthesis.
Klus GT; Nakamura J; Li JS; Ling YZ; Son C; Kemppainen JA; Wilson EM; Brodie AM
Cancer Res; 1996 Nov; 56(21):4956-64. PubMed ID: 8895750
[TBL] [Abstract][Full Text] [Related]
10. Synthesis of novel 17-(4'-formyl)pyrazolylandrosta-5,16-dienes and their derivatives as potent 17α-hydroxylase/C17,20-lyase inhibitors or antiproliferative agents depending on the substitution pattern of the heteroring.
Kovács D; Wölfling J; Szabó N; Szécsi M; Schelz Z; Zupkó I; Frank É
Eur J Med Chem; 2016 Sep; 120():284-95. PubMed ID: 27209562
[TBL] [Abstract][Full Text] [Related]
11. 17alpha-hydroxylase/17,20-lyase (p450(17alpha)) inhibitors in the treatment of prostate cancer: a review.
Owen CP
Anticancer Agents Med Chem; 2009 Jul; 9(6):613-26. PubMed ID: 19601745
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of phenyl alkyl imidazole-based compounds as potent inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).
Owen CP; Shahid I; Olusanjo MS; Patel CH; Dhanani S; Ahmed S
J Steroid Biochem Mol Biol; 2008 Jul; 111(1-2):117-27. PubMed ID: 18620055
[TBL] [Abstract][Full Text] [Related]
13. Novel steroidal vinyl fluorides as inhibitors of steroid C17(20) lyase.
Burkhart JP; Weintraub PM; Gates CA; Resvick RJ; Vaz RJ; Friedrich D; Angelastro MR; Bey P; Peet NP
Bioorg Med Chem; 2002 Apr; 10(4):929-34. PubMed ID: 11836100
[TBL] [Abstract][Full Text] [Related]
14. Determination of 17α-hydroxylase-C17,20-lyase (P45017α) enzyme activities and their inhibition by selected steroidal picolyl and picolinylidene compounds.
Szabó N; Ajduković JJ; Djurendić EA; Sakač MN; Ignáth I; Gardi J; Mahmoud G; Klisurić OR; Jovanović-Šanta S; Penov Gaši KM; Szécsi M
Acta Biol Hung; 2015 Mar; 66(1):41-51. PubMed ID: 25740437
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and activity of novel 16-dehydropregnenolone acetate derivatives as inhibitors of type 1 5α-reductase and on cancer cell line SK-LU-1.
Silva-Ortiz AV; Bratoeff E; Ramírez-Apan T; Heuze Y; Sánchez A; Soriano J; Cabeza M
Bioorg Med Chem; 2015 Dec; 23(24):7535-42. PubMed ID: 26631442
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, biochemical evaluation of a range of potent 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17alpha-Hydroxylase/17,20-Lyase (P45017alpha).
Shahid I; Patel CH; Dhanani S; Owen CP; Ahmed S
J Steroid Biochem Mol Biol; 2008 May; 110(1-2):18-29. PubMed ID: 18407491
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of 16α-amino-pregnenolone derivatives via ionic liquid-catalyzed aza-Michael addition and their evaluation as C
Szánti-Pintér E; Maksó L; Gömöry Á; Wouters J; Edina Herman B; Szécsi M; Mikle G; Kollár L; Skoda-Földes R
Steroids; 2017 Jul; 123():61-66. PubMed ID: 28502863
[TBL] [Abstract][Full Text] [Related]
18. Effects of novel 17alpha-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo.
Haidar S; Ehmer PB; Barassin S; Batzl-Hartmann C; Hartmann RW
J Steroid Biochem Mol Biol; 2003 Apr; 84(5):555-62. PubMed ID: 12767280
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of 21,21-difluoro-3 beta-hydroxy-20-methylpregna-5,20-diene and 5,16,20-triene as potential inhibitors of steroid C17(20) lyase.
Weintraub PM; Holland AK; Gates CA; Moore WR; Resvick RJ; Bey P; Peet NP
Bioorg Med Chem; 2003 Feb; 11(3):427-31. PubMed ID: 12517438
[TBL] [Abstract][Full Text] [Related]
20. Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases.
Salvador JA; Pinto RM; Silvestre SM
J Steroid Biochem Mol Biol; 2013 Sep; 137():199-222. PubMed ID: 23688836
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
