BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

454 related articles for article (PubMed ID: 29703751)

  • 21. Recombinant PaurTx-3, a spider toxin, inhibits sodium channels and decreases membrane excitability in DRG neurons.
    Chen M; Peng S; Wang L; Yang L; Si Y; Zhou X; Zhang Y; Liu Z
    Biochem Biophys Res Commun; 2020 Dec; 533(4):958-964. PubMed ID: 33004176
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The Role of Disulfide Bond Replacements in Analogues of the Tarantula Toxin ProTx-II and Their Effects on Inhibition of the Voltage-Gated Sodium Ion Channel Na
    Wright ZVF; McCarthy S; Dickman R; Reyes FE; Sanchez-Martinez S; Cryar A; Kilford I; Hall A; Takle AK; Topf M; Gonen T; Thalassinos K; Tabor AB
    J Am Chem Soc; 2017 Sep; 139(37):13063-13075. PubMed ID: 28880078
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Purification and Characterization of JZTx-14, a Potent Antagonist of Mammalian and Prokaryotic Voltage-Gated Sodium Channels.
    Zhang J; Tang D; Liu S; Hu H; Liang S; Tang C; Liu Z
    Toxins (Basel); 2018 Oct; 10(10):. PubMed ID: 30308978
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Chemical Synthesis, Proper Folding, Na
    Nicolas S; Zoukimian C; Bosmans F; Montnach J; Diochot S; Cuypers E; De Waard S; Béroud R; Mebs D; Craik D; Boturyn D; Lazdunski M; Tytgat J; De Waard M
    Toxins (Basel); 2019 Jun; 11(6):. PubMed ID: 31234412
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mapping the interaction site for the tarantula toxin hainantoxin-IV (β-TRTX-Hn2a) in the voltage sensor module of domain II of voltage-gated sodium channels.
    Cai T; Luo J; Meng E; Ding J; Liang S; Wang S; Liu Z
    Peptides; 2015 Jun; 68():148-56. PubMed ID: 25218973
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Spider Knottin Pharmacology at Voltage-Gated Sodium Channels and Their Potential to Modulate Pain Pathways.
    Dongol Y; Cardoso FC; Lewis RJ
    Toxins (Basel); 2019 Oct; 11(11):. PubMed ID: 31671792
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes.
    Bosmans F; Rash L; Zhu S; Diochot S; Lazdunski M; Escoubas P; Tytgat J
    Mol Pharmacol; 2006 Feb; 69(2):419-29. PubMed ID: 16267209
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop.
    Bende NS; Dziemborowicz S; Herzig V; Ramanujam V; Brown GW; Bosmans F; Nicholson GM; King GF; Mobli M
    FEBS J; 2015 Mar; 282(5):904-20. PubMed ID: 25559770
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa
    Neff RA; Flinspach M; Gibbs A; Shih AY; Minassian NA; Liu Y; Fellows R; Libiger O; Young S; Pennington MW; Hunter MJ; Wickenden AD
    J Biol Chem; 2020 Jan; 295(5):1315-1327. PubMed ID: 31871053
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel.
    Murray JK; Ligutti J; Liu D; Zou A; Poppe L; Li H; Andrews KL; Moyer BD; McDonough SI; Favreau P; Stöcklin R; Miranda LP
    J Med Chem; 2015 Mar; 58(5):2299-314. PubMed ID: 25658507
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Potency optimization of Huwentoxin-IV on hNav1.7: a neurotoxin TTX-S sodium-channel antagonist from the venom of the Chinese bird-eating spider Selenocosmia huwena.
    Revell JD; Lund PE; Linley JE; Metcalfe J; Burmeister N; Sridharan S; Jones C; Jermutus L; Bednarek MA
    Peptides; 2013 Jun; 44():40-6. PubMed ID: 23523779
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A novel tarantula toxin stabilizes the deactivated voltage sensor of bacterial sodium channel.
    Tang C; Zhou X; Nguyen PT; Zhang Y; Hu Z; Zhang C; Yarov-Yarovoy V; DeCaen PG; Liang S; Liu Z
    FASEB J; 2017 Jul; 31(7):3167-3178. PubMed ID: 28400471
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels.
    Tao H; Chen X; Lu M; Wu Y; Deng M; Zeng X; Liu Z; Liang S
    Toxicon; 2016 Mar; 111():13-21. PubMed ID: 26721415
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Molecular surface of JZTX-V (β-Theraphotoxin-Cj2a) interacting with voltage-gated sodium channel subtype NaV1.4.
    Luo J; Zhang Y; Gong M; Lu S; Ma Y; Zeng X; Liang S
    Toxins (Basel); 2014 Jul; 6(7):2177-93. PubMed ID: 25055801
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi.
    Sousa SR; Wingerd JS; Brust A; Bladen C; Ragnarsson L; Herzig V; Deuis JR; Dutertre S; Vetter I; Zamponi GW; King GF; Alewood PF; Lewis RJ
    PLoS One; 2017; 12(9):e0182848. PubMed ID: 28880874
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Recombinant production, bioconjugation and membrane binding studies ofPn3a, a selective Na
    Sharma G; Deuis JR; Jia X; Mueller A; Vetter I; Mobli M
    Biochem Pharmacol; 2020 Nov; 181():114148. PubMed ID: 32663452
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Molecular Interactions between Tarantula Toxins and Low-Voltage-Activated Calcium Channels.
    Salari A; Vega BS; Milescu LS; Milescu M
    Sci Rep; 2016 Apr; 6():23894. PubMed ID: 27045173
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structure of membrane-active toxin from crab spider Heriaeus melloteei suggests parallel evolution of sodium channel gating modifiers in Araneomorphae and Mygalomorphae.
    Berkut AA; Peigneur S; Myshkin MY; Paramonov AS; Lyukmanova EN; Arseniev AS; Grishin EV; Tytgat J; Shenkarev ZO; Vassilevski AA
    J Biol Chem; 2015 Jan; 290(1):492-504. PubMed ID: 25352595
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom.
    Lee SY; MacKinnon R
    Nature; 2004 Jul; 430(6996):232-5. PubMed ID: 15241419
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNa
    Giribaldi J; Chemin J; Tuifua M; Deuis JR; Mary R; Vetter I; Wilson DT; Daly NL; Schroeder CI; Bourinet E; Dutertre S
    FEBS J; 2023 Jul; 290(14):3688-3702. PubMed ID: 36912793
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 23.