366 related articles for article (PubMed ID: 29704008)
1. Impact of late-onset Alzheimer's genetic risk factors on beta-amyloid endocytic production.
Guimas Almeida C; Sadat Mirfakhar F; Perdigão C; Burrinha T
Cell Mol Life Sci; 2018 Jul; 75(14):2577-2589. PubMed ID: 29704008
[TBL] [Abstract][Full Text] [Related]
2. Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor
Andrew RJ; De Rossi P; Nguyen P; Kowalski HR; Recupero AJ; Guerbette T; Krause SV; Rice RC; Laury-Kleintop L; Wagner SL; Thinakaran G
J Biol Chem; 2019 Mar; 294(12):4477-4487. PubMed ID: 30692199
[TBL] [Abstract][Full Text] [Related]
3. Alzheimer's disease BIN1 coding variants increase intracellular Aβ levels by interfering with BACE1 recycling.
Perdigão C; Barata MA; Burrinha T; Guimas Almeida C
J Biol Chem; 2021 Sep; 297(3):101056. PubMed ID: 34375641
[TBL] [Abstract][Full Text] [Related]
4. Genomics of Alzheimer Disease: A Review.
Rosenberg RN; Lambracht-Washington D; Yu G; Xia W
JAMA Neurol; 2016 Jul; 73(7):867-74. PubMed ID: 27135718
[TBL] [Abstract][Full Text] [Related]
5. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease.
Cruchaga C; Karch CM; Jin SC; Benitez BA; Cai Y; Guerreiro R; Harari O; Norton J; Budde J; Bertelsen S; Jeng AT; Cooper B; Skorupa T; Carrell D; Levitch D; Hsu S; Choi J; Ryten M; Sassi C; Bras J; Gibbs RJ; Hernandez DG; Lupton MK; Powell J; Forabosco P; Ridge PG; Corcoran CD; Tschanz JT; Norton MC; Munger RG; Schmutz C; Leary M; Demirci FY; Bamne MN; Wang X; Lopez OL; Ganguli M; Medway C; Turton J; Lord J; Braae A; Barber I; Brown K; ; Pastor P; Lorenzo-Betancor O; Brkanac Z; Scott E; Topol E; Morgan K; Rogaeva E; Singleton A; Hardy J; Kamboh MI; George-Hyslop PS; Cairns N; Morris JC; Kauwe JSK; Goate AM
Nature; 2014 Jan; 505(7484):550-554. PubMed ID: 24336208
[TBL] [Abstract][Full Text] [Related]
6. Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
Ubelmann F; Burrinha T; Salavessa L; Gomes R; Ferreira C; Moreno N; Guimas Almeida C
EMBO Rep; 2017 Jan; 18(1):102-122. PubMed ID: 27895104
[TBL] [Abstract][Full Text] [Related]
7. CD2-associated protein (CD2AP) overexpression accelerates amyloid precursor protein (APP) transfer from early endosomes to the lysosomal degradation pathway.
Furusawa K; Takasugi T; Chiu YW; Hori Y; Tomita T; Fukuda M; Hisanaga SI
J Biol Chem; 2019 Jul; 294(28):10886-10899. PubMed ID: 31138646
[TBL] [Abstract][Full Text] [Related]
8. Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
Honda K; Saito Y; Saito H; Toyoda M; Abe R; Saito T; Saido TC; Michikawa M; Taru H; Sobu Y; Hata S; Nakaya T; Suzuki T
Neurobiol Aging; 2023 Mar; 123():63-74. PubMed ID: 36638682
[TBL] [Abstract][Full Text] [Related]
9. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
Tachibana M; Holm ML; Liu CC; Shinohara M; Aikawa T; Oue H; Yamazaki Y; Martens YA; Murray ME; Sullivan PM; Weyer K; Glerup S; Dickson DW; Bu G; Kanekiyo T
J Clin Invest; 2019 Mar; 129(3):1272-1277. PubMed ID: 30741718
[TBL] [Abstract][Full Text] [Related]
10. Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.
Fitz NF; Cronican AA; Saleem M; Fauq AH; Chapman R; Lefterov I; Koldamova R
J Neurosci; 2012 Sep; 32(38):13125-36. PubMed ID: 22993429
[TBL] [Abstract][Full Text] [Related]
11. The ubiquitin ligase UBE4B regulates amyloid precursor protein ubiquitination, endosomal trafficking, and amyloid β42 generation and secretion.
Gireud-Goss M; Reyes S; Tewari R; Patrizz A; Howe MD; Kofler J; Waxham MN; McCullough LD; Bean AJ
Mol Cell Neurosci; 2020 Oct; 108():103542. PubMed ID: 32841720
[TBL] [Abstract][Full Text] [Related]
12. Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms.
Li J; Kanekiyo T; Shinohara M; Zhang Y; LaDu MJ; Xu H; Bu G
J Biol Chem; 2012 Dec; 287(53):44593-601. PubMed ID: 23132858
[TBL] [Abstract][Full Text] [Related]
13. Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer's Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data.
Kocis P; Tolar M; Yu J; Sinko W; Ray S; Blennow K; Fillit H; Hey JA
CNS Drugs; 2017 Jun; 31(6):495-509. PubMed ID: 28435985
[TBL] [Abstract][Full Text] [Related]
14. APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Lin YT; Seo J; Gao F; Feldman HM; Wen HL; Penney J; Cam HP; Gjoneska E; Raja WK; Cheng J; Rueda R; Kritskiy O; Abdurrob F; Peng Z; Milo B; Yu CJ; Elmsaouri S; Dey D; Ko T; Yankner BA; Tsai LH
Neuron; 2018 Jun; 98(6):1141-1154.e7. PubMed ID: 29861287
[TBL] [Abstract][Full Text] [Related]
15. The cellular machinery of post-endocytic APP trafficking in Alzheimer's disease: A future target for therapeutic intervention?
Goldstein LSB; Das U
Prog Mol Biol Transl Sci; 2021; 177():109-122. PubMed ID: 33453937
[TBL] [Abstract][Full Text] [Related]
16. Alzheimer's disease risk genes and mechanisms of disease pathogenesis.
Karch CM; Goate AM
Biol Psychiatry; 2015 Jan; 77(1):43-51. PubMed ID: 24951455
[TBL] [Abstract][Full Text] [Related]
17. Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH.
Prasad H; Rao R
Proc Natl Acad Sci U S A; 2018 Jul; 115(28):E6640-E6649. PubMed ID: 29946028
[TBL] [Abstract][Full Text] [Related]
18. Genetics of Alzheimer's disease.
Chouraki V; Seshadri S
Adv Genet; 2014; 87():245-94. PubMed ID: 25311924
[TBL] [Abstract][Full Text] [Related]
19. The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner.
Bhattacharyya R; Teves CAF; Long A; Hofert M; Tanzi RE
Sci Rep; 2022 Mar; 12(1):3486. PubMed ID: 35241726
[TBL] [Abstract][Full Text] [Related]
20. PICALM Rescues Endocytic Defects Caused by the Alzheimer's Disease Risk Factor APOE4.
Narayan P; Sienski G; Bonner JM; Lin YT; Seo J; Baru V; Haque A; Milo B; Akay LA; Graziosi A; Freyzon Y; Landgraf D; Hesse WR; Valastyan J; Barrasa MI; Tsai LH; Lindquist S
Cell Rep; 2020 Oct; 33(1):108224. PubMed ID: 33027662
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
