318 related articles for article (PubMed ID: 29704441)
1. Improving culture performance and antibody production in CHO cell culture processes by reducing the Warburg effect.
Buchsteiner M; Quek LE; Gray P; Nielsen LK
Biotechnol Bioeng; 2018 Sep; 115(9):2315-2327. PubMed ID: 29704441
[TBL] [Abstract][Full Text] [Related]
2. Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.
Figueroa B; Ailor E; Osborne D; Hardwick JM; Reff M; Betenbaugh MJ
Biotechnol Bioeng; 2007 Jul; 97(4):877-92. PubMed ID: 17099908
[TBL] [Abstract][Full Text] [Related]
3. Magnetic resonance spectroscopic investigation of mitochondrial fuel metabolism and energetics in cultured human fibroblasts: effects of pyruvate dehydrogenase complex deficiency and dichloroacetate.
Simpson NE; Han Z; Berendzen KM; Sweeney CA; Oca-Cossio JA; Constantinidis I; Stacpoole PW
Mol Genet Metab; 2006; 89(1-2):97-105. PubMed ID: 16765624
[TBL] [Abstract][Full Text] [Related]
4. Process intensification in fed-batch production bioreactors using non-perfusion seed cultures.
Yongky A; Xu J; Tian J; Oliveira C; Zhao J; McFarland K; Borys MC; Li ZJ
MAbs; 2019; 11(8):1502-1514. PubMed ID: 31379298
[TBL] [Abstract][Full Text] [Related]
5. Establishment of a novel cell line, CHO-MK, derived from Chinese hamster ovary tissues for biologics manufacturing.
Masuda K; Kubota M; Nakazawa Y; Iwama C; Watanabe K; Ishikawa N; Tanabe Y; Kono S; Tanemura H; Takahashi S; Makino T; Okumura T; Horiuchi T; Nonaka K; Murakami S; Kamihira M; Omasa T
J Biosci Bioeng; 2024 Jun; 137(6):471-479. PubMed ID: 38472071
[TBL] [Abstract][Full Text] [Related]
6. Regulation of pyruvate dehydrogenase complex related to lactate switch in CHO cells.
Möller J; Bhat K; Guhl L; Pörtner R; Jandt U; Zeng AP
Eng Life Sci; 2021 Mar; 21(3-4):100-114. PubMed ID: 33716610
[TBL] [Abstract][Full Text] [Related]
7. Effects of dichloroacetate on the metabolism of glucose, pyruvate, acetate, 3-hydroxybutyrate and palmitate in rat diaphragm and heart muscle in vitro and on extraction of glucose, lactate, pyruvate and free fatty acids by dog heart in vivo.
McAllister A; Allison SP; Randle PJ
Biochem J; 1973 Aug; 134(4):1067-81. PubMed ID: 4762752
[TBL] [Abstract][Full Text] [Related]
8. Mechanisms by which dichloroacetate lowers lactic acid levels: the kinetic interrelationships between lactate, pyruvate, alanine, and glucose.
Jahoor F; Zhang XJ; Frazer E
Proc Soc Exp Biol Med; 1994 Jan; 205(1):44-51. PubMed ID: 7906882
[TBL] [Abstract][Full Text] [Related]
9. Impact of culture conditions, culture media volumes, and glucose content on metabolic properties of renal epithelial cell cultures. Are renal cells in tissue culture hypoxic?
Gstraunthaler G; Seppi T; Pfaller W
Cell Physiol Biochem; 1999; 9(3):150-72. PubMed ID: 10494029
[TBL] [Abstract][Full Text] [Related]
10. Effects of PDH activation by dichloroacetate in human skeletal muscle during exercise in hypoxia.
Parolin ML; Spriet LL; Hultman E; Matsos MP; Hollidge-Horvat MG; Jones NL; Heigenhauser GJ
Am J Physiol Endocrinol Metab; 2000 Oct; 279(4):E752-61. PubMed ID: 11001755
[TBL] [Abstract][Full Text] [Related]
11. Development of a fed-batch culture process for enhanced production of recombinant human antithrombin by Chinese hamster ovary cells.
Kuwae S; Ohda T; Tamashima H; Miki H; Kobayashi K
J Biosci Bioeng; 2005 Nov; 100(5):502-10. PubMed ID: 16384788
[TBL] [Abstract][Full Text] [Related]
12. Process development for a recombinant Chinese hamster ovary (CHO) cell line utilizing a metal induced and amplified metallothionein expression system.
Huang EP; Marquis CP; Gray PP
Biotechnol Bioeng; 2004 Nov; 88(4):437-50. PubMed ID: 15459913
[TBL] [Abstract][Full Text] [Related]
13. Dichloroacetate increases cell and antibody yields in batch cultures of a hybridoma cell line.
Murray K; Gull K; Dickson AJ
Biotechnol Bioeng; 1996 Feb; 49(4):377-82. PubMed ID: 18623591
[TBL] [Abstract][Full Text] [Related]
14. Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats.
Morand C; Besson C; Demigne C; Remesy C
Arch Biochem Biophys; 1994 Mar; 309(2):254-60. PubMed ID: 8135535
[TBL] [Abstract][Full Text] [Related]
15. Functional expression of human pyruvate carboxylase for reduced lactic acid formation of Chinese hamster ovary cells (DG44).
Kim SH; Lee GM
Appl Microbiol Biotechnol; 2007 Sep; 76(3):659-65. PubMed ID: 17583807
[TBL] [Abstract][Full Text] [Related]
16. Heuristic optimization of antibody production by Chinese hamster ovary cells.
Sandadi S; Ensari S; Kearns B
Biotechnol Prog; 2005; 21(5):1537-42. PubMed ID: 16209559
[TBL] [Abstract][Full Text] [Related]
17. Understanding the effect of temperature downshift on CHO cell growth, antibody titer and product quality by intracellular metabolite profiling and in vivo monitoring of redox state.
Zhu Z; Chen X; Li W; Zhuang Y; Zhao Y; Wang G
Biotechnol Prog; 2023; 39(4):e3352. PubMed ID: 37141532
[TBL] [Abstract][Full Text] [Related]
18. Debottlenecking and reformulating feed media for improved CHO cell growth and titer by data-driven and model-guided analyses.
Park SY; Choi DH; Song J; Park U; Cho H; Hong BH; Silberberg YR; Lee DY
Biotechnol J; 2023 Dec; 18(12):e2300126. PubMed ID: 37605365
[TBL] [Abstract][Full Text] [Related]
19. Effect of low culture temperature on specific productivity and transcription level of anti-4-1BB antibody in recombinant Chinese hamster ovary cells.
Yoon SK; Kim SH; Lee GM
Biotechnol Prog; 2003; 19(4):1383-6. PubMed ID: 12892507
[TBL] [Abstract][Full Text] [Related]
20. The effects of dichloroacetate on lactate accumulation and endurance in an exercising rat model.
Durkot MJ; De Garavilla L; Caretti D; Francesconi R
Int J Sports Med; 1995 Apr; 16(3):167-71. PubMed ID: 7649707
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]