752 related articles for article (PubMed ID: 29709199)
1. The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
Syed A; Tainer JA
Annu Rev Biochem; 2018 Jun; 87():263-294. PubMed ID: 29709199
[TBL] [Abstract][Full Text] [Related]
2. Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair.
Lafrance-Vanasse J; Williams GJ; Tainer JA
Prog Biophys Mol Biol; 2015 Mar; 117(2-3):182-193. PubMed ID: 25576492
[TBL] [Abstract][Full Text] [Related]
3. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
Williams RS; Williams JS; Tainer JA
Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
[TBL] [Abstract][Full Text] [Related]
4. NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation.
Anand R; Jasrotia A; Bundschuh D; Howard SM; Ranjha L; Stucki M; Cejka P
EMBO J; 2019 Apr; 38(7):. PubMed ID: 30787182
[TBL] [Abstract][Full Text] [Related]
5. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
[TBL] [Abstract][Full Text] [Related]
6. Multiple roles for MRE11 at uncapped telomeres.
Deng Y; Guo X; Ferguson DO; Chang S
Nature; 2009 Aug; 460(7257):914-8. PubMed ID: 19633651
[TBL] [Abstract][Full Text] [Related]
7. Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks.
Robison JG; Elliott J; Dixon K; Oakley GG
J Biol Chem; 2004 Aug; 279(33):34802-10. PubMed ID: 15180989
[TBL] [Abstract][Full Text] [Related]
8. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
[TBL] [Abstract][Full Text] [Related]
9. The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks.
Lee J; Dunphy WG
Mol Biol Cell; 2013 May; 24(9):1343-53. PubMed ID: 23468519
[TBL] [Abstract][Full Text] [Related]
10. Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling.
Henrich SM; Usadel C; Werwein E; Burdova K; Janscak P; Ferrari S; Hess D; Klempnauer KH
Sci Rep; 2017 Jan; 7():41663. PubMed ID: 28128338
[TBL] [Abstract][Full Text] [Related]
11. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
Ewald B; Sampath D; Plunkett W
Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
[TBL] [Abstract][Full Text] [Related]
12. A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans.
Chansel-Da Cruz M; Hohl M; Ceppi I; Kermasson L; Maggiorella L; Modesti M; de Villartay JP; Ileri T; Cejka P; Petrini JHJ; Revy P
Cell Rep; 2020 Dec; 33(13):108559. PubMed ID: 33378670
[TBL] [Abstract][Full Text] [Related]
13. Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Williams RS; Dodson GE; Limbo O; Yamada Y; Williams JS; Guenther G; Classen S; Glover JN; Iwasaki H; Russell P; Tainer JA
Cell; 2009 Oct; 139(1):87-99. PubMed ID: 19804755
[TBL] [Abstract][Full Text] [Related]
14. Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Rotheneder M; Stakyte K; van de Logt E; Bartho JD; Lammens K; Fan Y; Alt A; Kessler B; Jung C; Roos WP; Steigenberger B; Hopfner KP
Mol Cell; 2023 Jan; 83(2):167-185.e9. PubMed ID: 36577401
[TBL] [Abstract][Full Text] [Related]
15. MRE11/RAD50/NBS1: complex activities.
Assenmacher N; Hopfner KP
Chromosoma; 2004 Oct; 113(4):157-66. PubMed ID: 15309560
[TBL] [Abstract][Full Text] [Related]
16. Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.
Buis J; Wu Y; Deng Y; Leddon J; Westfield G; Eckersdorff M; Sekiguchi JM; Chang S; Ferguson DO
Cell; 2008 Oct; 135(1):85-96. PubMed ID: 18854157
[TBL] [Abstract][Full Text] [Related]
17. Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus.
Hollingworth R; Horniblow RD; Forrest C; Stewart GS; Grand RJ
J Virol; 2017 Nov; 91(22):. PubMed ID: 28855246
[TBL] [Abstract][Full Text] [Related]
18. Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks.
Williams GJ; Lees-Miller SP; Tainer JA
DNA Repair (Amst); 2010 Dec; 9(12):1299-306. PubMed ID: 21035407
[TBL] [Abstract][Full Text] [Related]
19. [Research Progress in the Roles of MRE11-RAD50-NBS1 Complex and Human Diseases].
Xu XH; Liu YD
Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2024 Apr; 46(2):232-241. PubMed ID: 38686720
[TBL] [Abstract][Full Text] [Related]
20. ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.
Hopfner KP
Bioessays; 2014 Dec; 36(12):1170-8. PubMed ID: 25213441
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
