These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 29717168)

  • 1. Allosteric modulation of the farnesoid X receptor by a small molecule.
    Gabler M; Kramer J; Schmidt J; Pollinger J; Weber J; Kaiser A; Löhr F; Proschak E; Schubert-Zsilavecz M; Merk D
    Sci Rep; 2018 May; 8(1):6846. PubMed ID: 29717168
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump.
    Cui J; Huang L; Zhao A; Lew JL; Yu J; Sahoo S; Meinke PT; Royo I; Pelaez F; Wright SD
    J Biol Chem; 2003 Mar; 278(12):10214-20. PubMed ID: 12525500
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes.
    Balasubramaniyan N; Luo Y; Sun AQ; Suchy FJ
    J Biol Chem; 2013 May; 288(19):13850-62. PubMed ID: 23546875
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bile salt excretory pump: biology and pathobiology.
    Suchy FJ; Ananthanarayanan M
    J Pediatr Gastroenterol Nutr; 2006 Jul; 43 Suppl 1():S10-6. PubMed ID: 16819395
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: molecular modeling with biological evaluation.
    Xu X; Lu Y; Chen L; Chen J; Luo X; Shen X
    Steroids; 2013 Sep; 78(9):813-22. PubMed ID: 23707573
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
    Liu X; Guo GL; Kong B; Hilburn DB; Hubchak SC; Park S; LeCuyer B; Hsieh A; Wang L; Fang D; Green RM
    Hepatology; 2018 Jul; 68(1):304-316. PubMed ID: 29377207
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor α (FXRα) in Stabilizing the Homodimerization of the Receptor.
    Xu X; Xu X; Liu P; Zhu ZY; Chen J; Fu HA; Chen LL; Hu LH; Shen X
    J Biol Chem; 2015 Aug; 290(32):19888-99. PubMed ID: 26100621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonists.
    Schmidt J; Schierle S; Gellrich L; Kaiser A; Merk D
    Bioorg Med Chem; 2018 Aug; 26(14):4240-4253. PubMed ID: 30026040
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nonacidic Farnesoid X Receptor Modulators.
    Flesch D; Cheung SY; Schmidt J; Gabler M; Heitel P; Kramer J; Kaiser A; Hartmann M; Lindner M; Lüddens-Dämgen K; Heering J; Lamers C; Lüddens H; Wurglics M; Proschak E; Schubert-Zsilavecz M; Merk D
    J Med Chem; 2017 Aug; 60(16):7199-7205. PubMed ID: 28749691
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The nuclear receptor FXR, but not LXR, up-regulates bile acid transporter expression in non-alcoholic fatty liver disease.
    Aguilar-Olivos NE; Carrillo-Córdova D; Oria-Hernández J; Sánchez-Valle V; Ponciano-Rodríguez G; Ramírez-Jaramillo M; Chablé-Montero F; Chávez-Tapia NC; Uribe M; Méndez-Sánchez N
    Ann Hepatol; 2015; 14(4):487-93. PubMed ID: 26019035
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters.
    Hoeke MO; Plass JR; Heegsma J; Geuken M; van Rijsbergen D; Baller JF; Kuipers F; Moshage H; Jansen PL; Faber KN
    Hepatology; 2009 Jan; 49(1):151-9. PubMed ID: 19111018
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.
    Pineda Torra I; Claudel T; Duval C; Kosykh V; Fruchart JC; Staels B
    Mol Endocrinol; 2003 Feb; 17(2):259-72. PubMed ID: 12554753
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition.
    Vaquero J; Monte MJ; Dominguez M; Muntané J; Marin JJ
    Biochem Pharmacol; 2013 Oct; 86(7):926-39. PubMed ID: 23928191
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Knockdown of ATP8B1 expression leads to specific downregulation of the bile acid sensor FXR in HepG2 cells: effect of the FXR agonist GW4064.
    Martínez-Fernández P; Hierro L; Jara P; Alvarez L
    Am J Physiol Gastrointest Liver Physiol; 2009 May; 296(5):G1119-29. PubMed ID: 19228886
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Progressive familial intrahepatic cholestasis, type 1, is associated with decreased farnesoid X receptor activity.
    Chen F; Ananthanarayanan M; Emre S; Neimark E; Bull LN; Knisely AS; Strautnieks SS; Thompson RJ; Magid MS; Gordon R; Balasubramanian N; Suchy FJ; Shneider BL
    Gastroenterology; 2004 Mar; 126(3):756-64. PubMed ID: 14988830
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters.
    Sissung TM; Huang PA; Hauke RJ; McCrea EM; Peer CJ; Barbier RH; Strope JD; Ley AM; Zhang M; Hong JA; Venzon D; Jackson JP; Brouwer KR; Grohar P; Glod J; Widemann BC; Heller T; Schrump DS; Figg WD
    Mol Pharmacol; 2019 Aug; 96(2):158-167. PubMed ID: 31175181
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene.
    Owsley E; Chiang JY
    Biochem Biophys Res Commun; 2003 Apr; 304(1):191-5. PubMed ID: 12705905
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Computational Insight into the Allosteric Activation Mechanism of Farnesoid X Receptor.
    Chen Y; Li J; Wu Z; Liu G; Li H; Tang Y; Li W
    J Chem Inf Model; 2020 Mar; 60(3):1540-1550. PubMed ID: 32097559
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro.
    Gao X; Fu T; Wang C; Ning C; Liu K; Liu Z; Sun H; Ma X; Huo X; Yang X; Zou M; Meng Q
    Toxicol Appl Pharmacol; 2018 Jun; 348():105-116. PubMed ID: 29660435
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump.
    Plass JR; Mol O; Heegsma J; Geuken M; Faber KN; Jansen PL; Müller M
    Hepatology; 2002 Mar; 35(3):589-96. PubMed ID: 11870371
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.