BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1406 related articles for article (PubMed ID: 29717933)

  • 1. The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis.
    Yamamoto M; Kensler TW; Motohashi H
    Physiol Rev; 2018 Jul; 98(3):1169-1203. PubMed ID: 29717933
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stress-sensing mechanisms and the physiological roles of the Keap1-Nrf2 system during cellular stress.
    Suzuki T; Yamamoto M
    J Biol Chem; 2017 Oct; 292(41):16817-16824. PubMed ID: 28842501
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Beyond repression of Nrf2: An update on Keap1.
    Kopacz A; Kloska D; Forman HJ; Jozkowicz A; Grochot-Przeczek A
    Free Radic Biol Med; 2020 Sep; 157():63-74. PubMed ID: 32234331
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An Overview of the Advantages of KEAP1-NRF2 System Activation During Inflammatory Disease Treatment.
    Keleku-Lukwete N; Suzuki M; Yamamoto M
    Antioxid Redox Signal; 2018 Dec; 29(17):1746-1755. PubMed ID: 28899203
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
    Uruno A; Motohashi H
    Nitric Oxide; 2011 Aug; 25(2):153-60. PubMed ID: 21385624
    [TBL] [Abstract][Full Text] [Related]  

  • 6. KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease.
    Dayalan Naidu S; Dinkova-Kostova AT
    Open Biol; 2020 Jun; 10(6):200105. PubMed ID: 32574549
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Measuring the Interaction of Transcription Factor Nrf2 with Its Negative Regulator Keap1 in Single Live Cells by an Improved FRET/FLIM Analysis.
    Dikovskaya D; Appleton PL; Bento-Pereira C; Dinkova-Kostova AT
    Chem Res Toxicol; 2019 Mar; 32(3):500-512. PubMed ID: 30793592
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Keap1 degradation by autophagy for the maintenance of redox homeostasis.
    Taguchi K; Fujikawa N; Komatsu M; Ishii T; Unno M; Akaike T; Motohashi H; Yamamoto M
    Proc Natl Acad Sci U S A; 2012 Aug; 109(34):13561-6. PubMed ID: 22872865
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism.
    Song MY; Lee DY; Chun KS; Kim EH
    Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33922165
    [TBL] [Abstract][Full Text] [Related]  

  • 10. From germ cells to neonates: the beginning of life and the KEAP1-NRF2 system.
    Matsumaru D; Motohashi H
    J Biochem; 2020 Feb; 167(2):133-138. PubMed ID: 31518425
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease.
    Tebay LE; Robertson H; Durant ST; Vitale SR; Penning TM; Dinkova-Kostova AT; Hayes JD
    Free Radic Biol Med; 2015 Nov; 88(Pt B):108-146. PubMed ID: 26122708
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.
    Dinkova-Kostova AT; Kostov RV; Canning P
    Arch Biochem Biophys; 2017 Mar; 617():84-93. PubMed ID: 27497696
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular Basis of the KEAP1-NRF2 Signaling Pathway.
    Suzuki T; Takahashi J; Yamamoto M
    Mol Cells; 2023 Mar; 46(3):133-141. PubMed ID: 36994473
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound.
    Ohnuma T; Nakayama S; Anan E; Nishiyama T; Ogura K; Hiratsuka A
    Toxicol Appl Pharmacol; 2010 Apr; 244(1):27-36. PubMed ID: 20026152
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update.
    Lu MC; Ji JA; Jiang ZY; You QD
    Med Res Rev; 2016 Sep; 36(5):924-63. PubMed ID: 27192495
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling.
    Bollong MJ; Lee G; Coukos JS; Yun H; Zambaldo C; Chang JW; Chin EN; Ahmad I; Chatterjee AK; Lairson LL; Schultz PG; Moellering RE
    Nature; 2018 Oct; 562(7728):600-604. PubMed ID: 30323285
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of a Potent Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Protein-Protein Interaction Inhibitor with Natural Proline Structure as a Cytoprotective Agent against Acetaminophen-Induced Hepatotoxicity.
    Lu MC; Zhang X; Wu F; Tan SJ; Zhao J; You QD; Jiang ZY
    J Med Chem; 2019 Jul; 62(14):6796-6813. PubMed ID: 31283229
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Point Mutation at C151 of
    Gatbonton-Schwager T; Yagishita Y; Joshi T; Wakabayashi N; Srinivasan H; Suzuki T; Yamamoto M; Kensler TW
    Mol Pharmacol; 2023 Aug; 104(2):51-61. PubMed ID: 37188495
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
    Itoh K; Mimura J; Yamamoto M
    Antioxid Redox Signal; 2010 Dec; 13(11):1665-78. PubMed ID: 20446768
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway.
    Baird L; Yamamoto M
    Mol Cell Biol; 2020 Jun; 40(13):. PubMed ID: 32284348
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 71.