These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
110 related articles for article (PubMed ID: 2971872)
1. A naturally occurring variation in thymidylate synthase structure is associated with a reduced response to 5-fluoro-2'-deoxyuridine in a human colon tumor cell line. Berger SH; Barbour KW; Berger FG Mol Pharmacol; 1988 Oct; 34(4):480-4. PubMed ID: 2971872 [TBL] [Abstract][Full Text] [Related]
2. Thymidylate synthase as a determinant of 5-fluoro-2'-deoxyuridine response in human colonic tumor cell lines. Berger SH; Berger FG Mol Pharmacol; 1988 Oct; 34(4):474-9. PubMed ID: 2971871 [TBL] [Abstract][Full Text] [Related]
3. Modulation of 5-fluoro-2'-deoxyuridine response by folinic acid in human colonic tumor cell lines: the role of thymidylate synthase. Davis ST; Berger SH Mol Pharmacol; 1989 Apr; 35(4):422-7. PubMed ID: 2523018 [TBL] [Abstract][Full Text] [Related]
4. Variation in human thymidylate synthase is associated with resistance to 5-fluoro-2'-deoxyuridine. Davis ST; Berger SH Mol Pharmacol; 1993 May; 43(5):702-8. PubMed ID: 8502227 [TBL] [Abstract][Full Text] [Related]
5. Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells. Berger SH; Jenh CH; Johnson LF; Berger FG Mol Pharmacol; 1985 Nov; 28(5):461-7. PubMed ID: 2932632 [TBL] [Abstract][Full Text] [Related]
6. A naturally occurring tyrosine to histidine replacement at residue 33 of human thymidylate synthase confers resistance to 5-fluoro-2'-deoxyuridine in mammalian and bacterial cells. Barbour KW; Hoganson DK; Berger SH; Berger FG Mol Pharmacol; 1992 Aug; 42(2):242-8. PubMed ID: 1355260 [TBL] [Abstract][Full Text] [Related]
7. Induction of thymidylate synthase associated with multidrug resistance in human breast and colon cancer cell lines. Chu E; Drake JC; Koeller DM; Zinn S; Jamis-Dow CA; Yeh GC; Allegra CJ Mol Pharmacol; 1991 Feb; 39(2):136-43. PubMed ID: 1704999 [TBL] [Abstract][Full Text] [Related]
8. Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents. Yawata A; Kim SR; Miyajima A; Kubo T; Ishida S; Saito Y; Nakajima Y; Katori N; Matsumoto Y; Fukuoka M; Ohno Y; Ozawa S; Sawada J Cancer Chemother Pharmacol; 2005 Nov; 56(5):465-72. PubMed ID: 15918040 [TBL] [Abstract][Full Text] [Related]
9. Functional effects of a naturally occurring amino acid substitution in human thymidylate synthase. Hughey CT; Barbour KW; Berger FG; Berger SH Mol Pharmacol; 1993 Aug; 44(2):316-23. PubMed ID: 8355668 [TBL] [Abstract][Full Text] [Related]
10. Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen. Grem JL; Danenberg KD; Behan K; Parr A; Young L; Danenberg PV; Nguyen D; Drake J; Monks A; Allegra CJ Clin Cancer Res; 2001 Apr; 7(4):999-1009. PubMed ID: 11309351 [TBL] [Abstract][Full Text] [Related]
11. Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules. Aschele C; Sobrero A; Faderan MA; Bertino JR Cancer Res; 1992 Apr; 52(7):1855-64. PubMed ID: 1532346 [TBL] [Abstract][Full Text] [Related]
12. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines. van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718 [TBL] [Abstract][Full Text] [Related]
13. Enhancement of 5-fluoro-2'-deoxyuridine antineoplastic activity by 5-benzyloxybenzyloxybenzylacyclouridine in a human colon carcinoma cell line. Chu E; Chu MY; Darnowski JW; Chen ZH; Pan BC; Chu SH Cancer Res; 1992 Apr; 52(7):1729-36. PubMed ID: 1532344 [TBL] [Abstract][Full Text] [Related]
14. Single amino acid substitution defines a naturally occurring genetic variant of human thymidylate synthase. Barbour KW; Berger SH; Berger FG Mol Pharmacol; 1990 Apr; 37(4):515-8. PubMed ID: 2325636 [TBL] [Abstract][Full Text] [Related]
15. Activity of thymidylate synthetase and its inhibition by 5-fluorouracil in highly enzyme-overproducing cells resistant to 10-propargyl-5,8-dideazafolate. Danenberg KD; Danenberg PV Mol Pharmacol; 1989 Aug; 36(2):219-23. PubMed ID: 2528057 [TBL] [Abstract][Full Text] [Related]
16. Defective facilitated diffusion of nucleosides, a primary mechanism of resistance to 5-fluoro-2'-deoxyuridine in the HCT-8 human carcinoma line. Sobrero AF; Moir RD; Bertino JR; Handschumacher RE Cancer Res; 1985 Jul; 45(7):3155-60. PubMed ID: 3159474 [TBL] [Abstract][Full Text] [Related]
17. The role of thymidylate synthase in the response to fluoropyrimidine-folinic acid combinations. Berger SH; Davis ST; Barbour KW; Berger FG Adv Exp Med Biol; 1988; 244():59-69. PubMed ID: 2977716 [TBL] [Abstract][Full Text] [Related]
18. Desensitization and sensitization of cells to fluoropyrimidines with different antisenses directed against thymidylate synthase messenger RNA. Ju J; Kane SE; Lenz HJ; Danenberg KD; Chu E; Danenberg PV Clin Cancer Res; 1998 Sep; 4(9):2229-36. PubMed ID: 9748143 [TBL] [Abstract][Full Text] [Related]
19. Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer. Xi Y; Nakajima G; Schmitz JC; Chu E; Ju J BMC Genomics; 2006 Apr; 7():68. PubMed ID: 16584549 [TBL] [Abstract][Full Text] [Related]
20. Detection and quantitation of thymidylate synthase mRNA in human colon adenocarcinoma cell line resistant to 5-fluorouracil by competitive PCR. Shibata J; Aiba K; Shibata H; Minowa S; Horikoshi N Anticancer Res; 1998; 18(3A):1457-63. PubMed ID: 9673356 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]