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2. Functional requirement of a wild-type allele for mutant IDH1 to suppress anchorage-independent growth through redox homeostasis. Tiburcio PDB; Xiao B; Berg S; Asper S; Lyne S; Zhang Y; Zhu X; Yan H; Huang LE Acta Neuropathol; 2018 Feb; 135(2):285-298. PubMed ID: 29288440 [TBL] [Abstract][Full Text] [Related]
3. Mutant IDH1 Cooperates with ATRX Loss to Drive the Alternative Lengthening of Telomere Phenotype in Glioma. Mukherjee J; Johannessen TC; Ohba S; Chow TT; Jones L; Pandita A; Pieper RO Cancer Res; 2018 Jun; 78(11):2966-2977. PubMed ID: 29545335 [TBL] [Abstract][Full Text] [Related]
4. IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response. Núñez FJ; Mendez FM; Kadiyala P; Alghamri MS; Savelieff MG; Garcia-Fabiani MB; Haase S; Koschmann C; Calinescu AA; Kamran N; Saxena M; Patel R; Carney S; Guo MZ; Edwards M; Ljungman M; Qin T; Sartor MA; Tagett R; Venneti S; Brosnan-Cashman J; Meeker A; Gorbunova V; Zhao L; Kremer DM; Zhang L; Lyssiotis CA; Jones L; Herting CJ; Ross JL; Hambardzumyan D; Hervey-Jumper S; Figueroa ME; Lowenstein PR; Castro MG Sci Transl Med; 2019 Feb; 11(479):. PubMed ID: 30760578 [TBL] [Abstract][Full Text] [Related]
5. Detection of ATRX and IDH1-R132H immunohistochemistry in the progression of 211 paired gliomas. Cai J; Zhu P; Zhang C; Li Q; Wang Z; Li G; Wang G; Yang P; Li J; Han B; Jiang C; Sun Y; Jiang T Oncotarget; 2016 Mar; 7(13):16384-95. PubMed ID: 26918938 [TBL] [Abstract][Full Text] [Related]
6. Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1 Waitkus MS; Pirozzi CJ; Moure CJ; Diplas BH; Hansen LJ; Carpenter AB; Yang R; Wang Z; Ingram BO; Karoly ED; Mohney RP; Spasojevic I; McLendon RE; Friedman HS; He Y; Bigner DD; Yan H Cancer Res; 2018 Jan; 78(1):36-50. PubMed ID: 29097607 [TBL] [Abstract][Full Text] [Related]
7. Monoallelic IDH1 R132H Mutation Mediates Glioma Cell Response to Anticancer Therapies via Induction of Senescence. Zhan D; Ma D; Wei S; Lal B; Fu Y; Eberhart C; Laterra J; Ying M; Li Y; Meeker A; Lopez-Bertoni H; Xia S Mol Cancer Res; 2021 Nov; 19(11):1878-1888. PubMed ID: 34348994 [TBL] [Abstract][Full Text] [Related]
8. IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis. Gao Y; de Wit M; Struys EA; van der Linde HCZ; Salomons GS; Lamfers MLM; Willemsen R; Sillevis Smitt PAE; French PJ PLoS One; 2018; 13(6):e0199737. PubMed ID: 29953513 [TBL] [Abstract][Full Text] [Related]
9. Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric glioma. Raghunathan A; Olar A; Vogel H; Parker JR; Coventry SC; Debski R; Albarracin CT; Aldape KD; Cahill DP; Powell SZ; Fuller GN Ann Diagn Pathol; 2012 Aug; 16(4):255-9. PubMed ID: 22445362 [TBL] [Abstract][Full Text] [Related]
10. Inhibition of D-2HG leads to upregulation of a proinflammatory gene signature in a novel HLA-A2/HLA-DR1 transgenic mouse model of IDH1R132H-expressing glioma. Chuntova P; Yamamichi A; Chen T; Narayanaswamy R; Ronseaux S; Hudson C; Tron AE; Hyer ML; Montoya M; Mende AL; Nejo T; Downey KM; Diebold D; Lu M; Nicolay B; Okada H J Immunother Cancer; 2022 May; 10(5):. PubMed ID: 35606087 [TBL] [Abstract][Full Text] [Related]
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13. A vaccine targeting mutant IDH1 induces antitumour immunity. Schumacher T; Bunse L; Pusch S; Sahm F; Wiestler B; Quandt J; Menn O; Osswald M; Oezen I; Ott M; Keil M; Balß J; Rauschenbach K; Grabowska AK; Vogler I; Diekmann J; Trautwein N; Eichmüller SB; Okun J; Stevanović S; Riemer AB; Sahin U; Friese MA; Beckhove P; von Deimling A; Wick W; Platten M Nature; 2014 Aug; 512(7514):324-7. PubMed ID: 25043048 [TBL] [Abstract][Full Text] [Related]
14. A high-sensitive HMab-2 specifically detects IDH1-R132H, the most common IDH mutation in gliomas. Fujii Y; Ogasawara S; Oki H; Liu X; Kaneko MK; Takano S; Kato Y Biochem Biophys Res Commun; 2015 Oct; 466(4):733-9. PubMed ID: 26381180 [TBL] [Abstract][Full Text] [Related]
15. Demethylation and epigenetic modification with 5-azacytidine reduces IDH1 mutant glioma growth in combination with temozolomide. Yamashita AS; da Costa Rosa M; Borodovsky A; Festuccia WT; Chan T; Riggins GJ Neuro Oncol; 2019 Feb; 21(2):189-200. PubMed ID: 30184215 [TBL] [Abstract][Full Text] [Related]
16. Isocitrate dehydrogenase 1 mutation enhances 24(S)-hydroxycholesterol production and alters cholesterol homeostasis in glioma. Yang R; Zhao Y; Gu Y; Yang Y; Gao X; Yuan Y; Xiao L; Zhang J; Sun C; Yang H; Qin J; Li J; Zhang F; Zhang L; Ye J Oncogene; 2020 Oct; 39(40):6340-6353. PubMed ID: 32855525 [TBL] [Abstract][Full Text] [Related]
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19. R132H mutation in IDH1 gene reduces proliferation, cell survival and invasion of human glioma by downregulating Wnt/β-catenin signaling. Cui D; Ren J; Shi J; Feng L; Wang K; Zeng T; Jin Y; Gao L Int J Biochem Cell Biol; 2016 Apr; 73():72-81. PubMed ID: 26860959 [TBL] [Abstract][Full Text] [Related]
20. An analysis of the prognostic value of IDH1 (isocitrate dehydrogenase 1) mutation in Polish glioma patients. Lewandowska MA; Furtak J; Szylberg T; Roszkowski K; Windorbska W; Rytlewska J; Jóźwicki W Mol Diagn Ther; 2014 Feb; 18(1):45-53. PubMed ID: 23934769 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]