124 related articles for article (PubMed ID: 29723786)
1. Design, synthesis and biological activities of 2,3-dihydroquinazolin-4(1H)-one derivatives as TRPM2 inhibitors.
Zhang H; Liu H; Luo X; Wang Y; Liu Y; Jin H; Liu Z; Yang W; Yu P; Zhang L; Zhang L
Eur J Med Chem; 2018 May; 152():235-252. PubMed ID: 29723786
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological activities of benzo[d]imidazo[1,2-a]imidazole derivatives as TRPM2-specfic inhibitors.
Zhao S; Zhang H; Jin H; Cai X; Zhang R; Jin Z; Yang W; Yu P; Zhang L; Liu Z
Eur J Med Chem; 2021 Dec; 225():113750. PubMed ID: 34416664
[TBL] [Abstract][Full Text] [Related]
3. Selective inhibition of TRPM2 channel by two novel synthesized ADPR analogues.
Luo X; Li M; Zhan K; Yang W; Zhang L; Wang K; Yu P; Zhang L
Chem Biol Drug Des; 2018 Feb; 91(2):552-566. PubMed ID: 29034580
[TBL] [Abstract][Full Text] [Related]
4. Characterization and Optimization of the Novel Transient Receptor Potential Melastatin 2 Antagonist tatM2NX.
Cruz-Torres I; Backos DS; Herson PS
Mol Pharmacol; 2020 Feb; 97(2):102-111. PubMed ID: 31772034
[TBL] [Abstract][Full Text] [Related]
5. Scalaradial Is a Potent Inhibitor of Transient Receptor Potential Melastatin 2 (TRPM2) Ion Channels.
Starkus JG; Poerzgen P; Layugan K; Kawabata KG; Goto JI; Suzuki S; Myers G; Kelly M; Penner R; Fleig A; Horgen FD
J Nat Prod; 2017 Oct; 80(10):2741-2750. PubMed ID: 29019677
[TBL] [Abstract][Full Text] [Related]
6. The Discovery of Novel ACA Derivatives as Specific TRPM2 Inhibitors that Reduce Ischemic Injury Both In Vitro and In Vivo.
Zhang H; Yu P; Lin H; Jin Z; Zhao S; Zhang Y; Xu Q; Jin H; Liu Z; Yang W; Zhang L
J Med Chem; 2021 Apr; 64(7):3976-3996. PubMed ID: 33784097
[TBL] [Abstract][Full Text] [Related]
7. Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry.
Shimizu S; Yonezawa R; Hagiwara T; Yoshida T; Takahashi N; Hamano S; Negoro T; Toda T; Wakamori M; Mori Y; Ishii M
Eur J Pharmacol; 2014 Nov; 742():22-30. PubMed ID: 25179574
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, crystal structure determination, biological screening and docking studies of N
Sultana N; Sarfraz M; Tanoli ST; Akram MS; Sadiq A; Rashid U; Tariq MI
Bioorg Chem; 2017 Jun; 72():256-267. PubMed ID: 28495556
[TBL] [Abstract][Full Text] [Related]
9. A dual role of transient receptor potential melastatin 2 channel in cytotoxicity induced by silica nanoparticles.
Yu P; Li J; Jiang J; Zhao Z; Hui Z; Zhang J; Zheng Y; Ling D; Wang L; Jiang LH; Luo J; Zhu X; Yang W
Sci Rep; 2015 Dec; 5():18171. PubMed ID: 26656285
[TBL] [Abstract][Full Text] [Related]
10. Medicinal chemistry perspective of TRPM2 channel inhibitors: where we are and where we might be heading?
Zhang H; Zhao S; Yu J; Yang W; Liu Z; Zhang L
Drug Discov Today; 2020 Dec; 25(12):2326-2334. PubMed ID: 33065292
[TBL] [Abstract][Full Text] [Related]
11. TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes.
Roberge S; Roussel J; Andersson DC; Meli AC; Vidal B; Blandel F; Lanner JT; Le Guennec JY; Katz A; Westerblad H; Lacampagne A; Fauconnier J
Cardiovasc Res; 2014 Jul; 103(1):90-9. PubMed ID: 24802330
[TBL] [Abstract][Full Text] [Related]
12. Divalent copper is a potent extracellular blocker for TRPM2 channel.
Zeng B; Chen GL; Xu SZ
Biochem Biophys Res Commun; 2012 Jul; 424(2):279-84. PubMed ID: 22750002
[TBL] [Abstract][Full Text] [Related]
13. Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators.
Bertamino A; Ostacolo C; Ambrosino P; Musella S; Di Sarno V; Ciaglia T; Soldovieri MV; Iraci N; Fernandez Carvajal A; de la Torre-Martinez R; Ferrer-Montiel A; Gonzalez Muniz R; Novellino E; Taglialatela M; Campiglia P; Gomez-Monterrey I
J Med Chem; 2016 Mar; 59(5):2179-91. PubMed ID: 26847872
[TBL] [Abstract][Full Text] [Related]
14. TRPM2 channel properties, functions and therapeutic potentials.
Jiang LH; Yang W; Zou J; Beech DJ
Expert Opin Ther Targets; 2010 Sep; 14(9):973-88. PubMed ID: 20670202
[TBL] [Abstract][Full Text] [Related]
15. Protective Effects of Duloxetine against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition.
Toda T; Yamamoto S; Umehara N; Mori Y; Wakamori M; Shimizu S
J Pharmacol Exp Ther; 2019 Feb; 368(2):246-254. PubMed ID: 30523061
[TBL] [Abstract][Full Text] [Related]
16. Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists.
Moreau C; Kirchberger T; Swarbrick JM; Bartlett SJ; Fliegert R; Yorgan T; Bauche A; Harneit A; Guse AH; Potter BV
J Med Chem; 2013 Dec; 56(24):10079-102. PubMed ID: 24304219
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, biological evaluation and docking studies of 2,3-dihydroquinazolin-4(1H)-one derivatives as inhibitors of cholinesterases.
Sarfraz M; Sultana N; Rashid U; Akram MS; Sadiq A; Tariq MI
Bioorg Chem; 2017 Feb; 70():237-244. PubMed ID: 28126287
[TBL] [Abstract][Full Text] [Related]
18. Novel role of reactive oxygen species-activated Trp melastatin channel-2 in mediating angiogenesis and postischemic neovascularization.
Mittal M; Urao N; Hecquet CM; Zhang M; Sudhahar V; Gao XP; Komarova Y; Ushio-Fukai M; Malik AB
Arterioscler Thromb Vasc Biol; 2015 Apr; 35(4):877-87. PubMed ID: 25675998
[TBL] [Abstract][Full Text] [Related]
19. TRPM2: a potential drug target to retard oxidative stress.
Li J; Gao Y; Bao X; Li F; Yao W; Feng Z; Yin Y
Front Biosci (Landmark Ed); 2017 Mar; 22(9):1427-1438. PubMed ID: 28199210
[TBL] [Abstract][Full Text] [Related]
20. Activation of TRPM2 and TRPV1 Channels in Dorsal Root Ganglion by NADPH Oxidase and Protein Kinase C Molecular Pathways: a Patch Clamp Study.
Nazıroğlu M
J Mol Neurosci; 2017 Mar; 61(3):425-435. PubMed ID: 28097492
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
