BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 29724201)

  • 21. Auranofin induces apoptosis by ROS-mediated ER stress and mitochondrial dysfunction and displayed synergistic lethality with piperlongumine in gastric cancer.
    Zou P; Chen M; Ji J; Chen W; Chen X; Ying S; Zhang J; Zhang Z; Liu Z; Yang S; Liang G
    Oncotarget; 2015 Nov; 6(34):36505-21. PubMed ID: 26431378
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Benzimidazol-2-ylidene gold(I) complexes are thioredoxin reductase inhibitors with multiple antitumor properties.
    Rubbiani R; Kitanovic I; Alborzinia H; Can S; Kitanovic A; Onambele LA; Stefanopoulou M; Geldmacher Y; Sheldrick WS; Wolber G; Prokop A; Wölfl S; Ott I
    J Med Chem; 2010 Dec; 53(24):8608-18. PubMed ID: 21082862
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: a novel synergistic therapeutic approach.
    Kiebala M; Skalska J; Casulo C; Brookes PS; Peterson DR; Hilchey SP; Dai Y; Grant S; Maggirwar SB; Bernstein SH
    Exp Hematol; 2015 Feb; 43(2):89-99. PubMed ID: 25448488
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation.
    Cox AG; Brown KK; Arner ES; Hampton MB
    Biochem Pharmacol; 2008 Oct; 76(9):1097-109. PubMed ID: 18789312
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Ruthenium polypyridyl complexes as inducer of ROS-mediated apoptosis in cancer cells by targeting thioredoxin reductase.
    Luo Z; Yu L; Yang F; Zhao Z; Yu B; Lai H; Wong KH; Ngai SM; Zheng W; Chen T
    Metallomics; 2014 Aug; 6(8):1480-90. PubMed ID: 24823440
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Auranofin inhibits the proliferation of lung cancer cells via necrosis and caspase‑dependent apoptosis.
    Cui XY; Park SH; Park WH
    Oncol Rep; 2020 Dec; 44(6):2715-2724. PubMed ID: 33125149
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells.
    Marzano C; Gandin V; Folda A; Scutari G; Bindoli A; Rigobello MP
    Free Radic Biol Med; 2007 Mar; 42(6):872-81. PubMed ID: 17320769
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo.
    Huang H; Liao Y; Liu N; Hua X; Cai J; Yang C; Long H; Zhao C; Chen X; Lan X; Zang D; Wu J; Li X; Shi X; Wang X; Liu J
    Oncotarget; 2016 Jan; 7(3):2796-808. PubMed ID: 26625200
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibition of thioredoxin reductase (TrxR) triggers oxidative stress-induced apoptosis in filarial nematode Setaria cervi channelized through ASK-1-p38 mediated caspase activation.
    Joardar N; Sen A; Rath J; Babu SPS
    Mol Biochem Parasitol; 2021 Mar; 242():111364. PubMed ID: 33639230
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Auranofin, a thioredoxin reductase inhibitor, causes platelet death through calcium overload.
    Harper MT
    Platelets; 2019; 30(1):98-104. PubMed ID: 29194002
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer.
    Freire Boullosa L; Van Loenhout J; Flieswasser T; De Waele J; Hermans C; Lambrechts H; Cuypers B; Laukens K; Bartholomeus E; Siozopoulou V; De Vos WH; Peeters M; Smits ELJ; Deben C
    Redox Biol; 2021 Jun; 42():101949. PubMed ID: 33812801
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Synergistic induction of apoptosis by combination treatment with mesupron and auranofin in human breast cancer cells.
    Lee JE; Kwon YJ; Baek HS; Ye DJ; Cho E; Choi HK; Oh KS; Chun YJ
    Arch Pharm Res; 2017 Jun; 40(6):746-759. PubMed ID: 28560500
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design and synthesis of benzylidenecyclohexenones as TrxR inhibitors displaying high anticancer activity and inducing ROS, apoptosis, and autophagy.
    Qian J; Xu Z; Meng C; Liu J; Hsu PL; Li Y; Zhu W; Yang Y; Morris-Natschke SL; Lee KH; Zhang Y; Ling Y
    Eur J Med Chem; 2020 Oct; 204():112610. PubMed ID: 32736231
    [TBL] [Abstract][Full Text] [Related]  

  • 34. [Potential Anticancer Activity of Auranofin].
    Momose I; Onodera T; Kawada M
    Yakugaku Zasshi; 2021; 141(3):315-321. PubMed ID: 33642497
    [TBL] [Abstract][Full Text] [Related]  

  • 35. ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin.
    Wen C; Wang H; Wu X; He L; Zhou Q; Wang F; Chen S; Huang L; Chen J; Wang H; Ye W; Li W; Yang X; Liu H; Peng J
    Cell Death Dis; 2019 Oct; 10(11):809. PubMed ID: 31649256
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibition of thioredoxin reductase by mansonone F analogues: Implications for anticancer activity.
    Liu Z; Huang SL; Li MM; Huang ZS; Lee KS; Gu LQ
    Chem Biol Interact; 2009 Jan; 177(1):48-57. PubMed ID: 18822278
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Ruthenium(II) salicylate complexes inducing ROS-mediated apoptosis by targeting thioredoxin reductase.
    Chen JC; Zhang Y; Jie XM; She J; Dongye GZ; Zhong Y; Deng YY; Wang J; Guo BY; Chen LM
    J Inorg Biochem; 2019 Apr; 193():112-123. PubMed ID: 30711557
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Unveiling the Potential of Innovative Gold(I) and Silver(I) Selenourea Complexes as Anticancer Agents Targeting TrxR and Cellular Redox Homeostasis.
    De Franco M; Saab M; Porchia M; Marzano C; Nolan SP; Nahra F; Van Hecke K; Gandin V
    Chemistry; 2022 Dec; 28(70):e202201898. PubMed ID: 36106679
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia.
    Fiskus W; Saba N; Shen M; Ghias M; Liu J; Gupta SD; Chauhan L; Rao R; Gunewardena S; Schorno K; Austin CP; Maddocks K; Byrd J; Melnick A; Huang P; Wiestner A; Bhalla KN
    Cancer Res; 2014 May; 74(9):2520-32. PubMed ID: 24599128
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Elimination of stem-like cancer cell side-population by auranofin through modulation of ROS and glycolysis.
    Hou GX; Liu PP; Zhang S; Yang M; Liao J; Yang J; Hu Y; Jiang WQ; Wen S; Huang P
    Cell Death Dis; 2018 Jan; 9(2):89. PubMed ID: 29367724
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.