434 related articles for article (PubMed ID: 29725819)
1. Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients.
Bennett CL; Dastidar SG; Ling SC; Malik B; Ashe T; Wadhwa M; Miller DB; Lee C; Mitchell MB; van Es MA; Grunseich C; Chen Y; Sopher BL; Greensmith L; Cleveland DW; La Spada AR
Acta Neuropathol; 2018 Sep; 136(3):425-443. PubMed ID: 29725819
[TBL] [Abstract][Full Text] [Related]
2. Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4.
Kannan A; Cuartas J; Gangwani P; Branzei D; Gangwani L
Brain; 2022 Sep; 145(9):3072-3094. PubMed ID: 35045161
[TBL] [Abstract][Full Text] [Related]
3. SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation.
Richard P; Feng S; Tsai YL; Li W; Rinchetti P; Muhith U; Irizarry-Cole J; Stolz K; Sanz LA; Hartono S; Hoque M; Tadesse S; Seitz H; Lotti F; Hirano M; Chédin F; Tian B; Manley JL
Autophagy; 2021 Aug; 17(8):1889-1906. PubMed ID: 32686621
[TBL] [Abstract][Full Text] [Related]
4. DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4).
Chen YZ; Bennett CL; Huynh HM; Blair IP; Puls I; Irobi J; Dierick I; Abel A; Kennerson ML; Rabin BA; Nicholson GA; Auer-Grumbach M; Wagner K; De Jonghe P; Griffin JW; Fischbeck KH; Timmerman V; Cornblath DR; Chance PF
Am J Hum Genet; 2004 Jun; 74(6):1128-35. PubMed ID: 15106121
[TBL] [Abstract][Full Text] [Related]
5. Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity.
Bennett CL; Dastidar S; Arnold FJ; McKinstry SU; Stockford C; Freibaum BD; Sopher BL; Wu M; Seidner G; Joiner W; Taylor JP; West RJH; La Spada AR
Acta Neuropathol Commun; 2023 Oct; 11(1):164. PubMed ID: 37845749
[TBL] [Abstract][Full Text] [Related]
6. Role of Senataxin in Amyotrophic Lateral Sclerosis.
Tsui A; Kouznetsova VL; Kesari S; Fiala M; Tsigelny IF
J Mol Neurosci; 2023 Dec; 73(11-12):996-1009. PubMed ID: 37982993
[TBL] [Abstract][Full Text] [Related]
7. Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4.
Campisi L; Chizari S; Ho JSY; Gromova A; Arnold FJ; Mosca L; Mei X; Fstkchyan Y; Torre D; Beharry C; Garcia-Forn M; Jiménez-Alcázar M; Korobeynikov VA; Prazich J; Fayad ZA; Seldin MM; De Rubeis S; Bennett CL; Ostrow LW; Lunetta C; Squatrito M; Byun M; Shneider NA; Jiang N; La Spada AR; Marazzi I
Nature; 2022 Jun; 606(7916):945-952. PubMed ID: 35732742
[TBL] [Abstract][Full Text] [Related]
8. Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide.
Bennett CL; Chen Y; Vignali M; Lo RS; Mason AG; Unal A; Huq Saifee NP; Fields S; La Spada AR
PLoS One; 2013; 8(11):e78837. PubMed ID: 24244371
[TBL] [Abstract][Full Text] [Related]
9. Unusual electrophysiological findings in a Chinese ALS 4 family with SETX-L389S mutation: a three-year follow-up.
Lei L; Chen H; Lu Y; Zhu W; Ouyang Y; Duo J; Chen Z; Da Y
J Neurol; 2021 Mar; 268(3):1050-1058. PubMed ID: 32997296
[TBL] [Abstract][Full Text] [Related]
10. Senataxin, A Novel Helicase at the Interface of RNA Transcriptome Regulation and Neurobiology: From Normal Function to Pathological Roles in Motor Neuron Disease and Cerebellar Degeneration.
Bennett CL; La Spada AR
Adv Neurobiol; 2018; 20():265-281. PubMed ID: 29916023
[TBL] [Abstract][Full Text] [Related]
11. SUMOylated Senataxin functions in genome stability, RNA degradation, and stress granule disassembly, and is linked with inherited ataxia and motor neuron disease.
Bennett CL; La Spada AR
Mol Genet Genomic Med; 2021 Dec; 9(12):e1745. PubMed ID: 34263556
[TBL] [Abstract][Full Text] [Related]
12. De novo pathogenic variant in SETX causes a rapidly progressive neurodegenerative disorder of early childhood-onset with severe axonal polyneuropathy.
Hadjinicolaou A; Ngo KJ; Conway DY; Provias JP; Baker SK; Brady LI; Bennett CL; La Spada AR; Fogel BL; Yoon G
Acta Neuropathol Commun; 2021 Dec; 9(1):194. PubMed ID: 34922620
[TBL] [Abstract][Full Text] [Related]
13. The SETX missense variation spectrum as evaluated in patients with ALS4-like motor neuron diseases.
Arning L; Epplen JT; Rahikkala E; Hendrich C; Ludolph AC; Sperfeld AD
Neurogenetics; 2013 Feb; 14(1):53-61. PubMed ID: 23129421
[TBL] [Abstract][Full Text] [Related]
14. Clinical and Molecular Aspects of Senataxin Mutations in Amyotrophic Lateral Sclerosis 4.
Grunseich C; Patankar A; Amaya J; Watts JA; Li D; Ramirez P; Schindler AB; Fischbeck KH; Cheung VG
Ann Neurol; 2020 Apr; 87(4):547-555. PubMed ID: 31957062
[TBL] [Abstract][Full Text] [Related]
15. Senataxin mutations and amyotrophic lateral sclerosis.
Hirano M; Quinzii CM; Mitsumoto H; Hays AP; Roberts JK; Richard P; Rowland LP
Amyotroph Lateral Scler; 2011 May; 12(3):223-7. PubMed ID: 21190393
[TBL] [Abstract][Full Text] [Related]
16. Senataxin: A key actor in RNA metabolism, genome integrity and neurodegeneration.
Giannini M; Porrua O
Biochimie; 2024 Feb; 217():10-19. PubMed ID: 37558082
[TBL] [Abstract][Full Text] [Related]
17. Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2.
Fogel BL; Cho E; Wahnich A; Gao F; Becherel OJ; Wang X; Fike F; Chen L; Criscuolo C; De Michele G; Filla A; Collins A; Hahn AF; Gatti RA; Konopka G; Perlman S; Lavin MF; Geschwind DH; Coppola G
Hum Mol Genet; 2014 Sep; 23(18):4758-69. PubMed ID: 24760770
[TBL] [Abstract][Full Text] [Related]
18. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
[TBL] [Abstract][Full Text] [Related]
19. [A case of sporadic amyotrophic lateral sclerosis (ALS) with Senataxin (SETX) gene variant].
Beppu S; Ikenaka K; Yabumoto T; Todo K; Hashiguchi A; Takashima H; Mochizuki H
Rinsho Shinkeigaku; 2022 Mar; 62(3):205-210. PubMed ID: 35228463
[TBL] [Abstract][Full Text] [Related]
20. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis.
Ditsworth D; Maldonado M; McAlonis-Downes M; Sun S; Seelman A; Drenner K; Arnold E; Ling SC; Pizzo D; Ravits J; Cleveland DW; Da Cruz S
Acta Neuropathol; 2017 Jun; 133(6):907-922. PubMed ID: 28357566
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
