BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 29733583)

  • 21. Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues.
    Ellison M; Feng ZP; Park AJ; Zhang X; Olivera BM; McIntosh JM; Norton RS
    J Mol Biol; 2008 Apr; 377(4):1216-27. PubMed ID: 18295795
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins.
    Cuny H; Kompella SN; Tae HS; Yu R; Adams DJ
    J Biol Chem; 2016 Nov; 291(45):23779-23792. PubMed ID: 27646000
    [TBL] [Abstract][Full Text] [Related]  

  • 23. d-Amino Acid Substitution of α-Conotoxin RgIA Identifies its Critical Residues and Improves the Enzymatic Stability.
    Ren J; Zhu X; Xu P; Li R; Fu Y; Dong S; Zhangsun D; Wu Y; Luo S
    Mar Drugs; 2019 Feb; 17(3):. PubMed ID: 30823399
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor.
    Yu R; Kompella SN; Adams DJ; Craik DJ; Kaas Q
    J Med Chem; 2013 May; 56(9):3557-67. PubMed ID: 23566299
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Development of Conformationally Constrained α-RgIA Analogues as Stable Peptide Antagonists of Human α9α10 Nicotinic Acetylcholine Receptors.
    Zheng N; Christensen SB; Blakely A; Dowell C; Purushottam L; McIntosh JM; Chou DH
    J Med Chem; 2020 Aug; 63(15):8380-8387. PubMed ID: 32597184
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Alanine-Scanning Mutagenesis of α-Conotoxin GI Reveals the Residues Crucial for Activity at the Muscle Acetylcholine Receptor.
    Ning J; Li R; Ren J; Zhangsun D; Zhu X; Wu Y; Luo S
    Mar Drugs; 2018 Dec; 16(12):. PubMed ID: 30551685
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Molecular interaction of α-conotoxin RgIA with the rat α9α10 nicotinic acetylcholine receptor.
    Azam L; Papakyriakou A; Zouridakis M; Giastas P; Tzartos SJ; McIntosh JM
    Mol Pharmacol; 2015 May; 87(5):855-64. PubMed ID: 25740413
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.
    Luo S; Zhangsun D; Harvey PJ; Kaas Q; Wu Y; Zhu X; Hu Y; Li X; Tsetlin VI; Christensen S; Romero HK; McIntyre M; Dowell C; Baxter JC; Elmslie KS; Craik DJ; McIntosh JM
    Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4026-35. PubMed ID: 26170295
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Are alpha9alpha10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?
    Nevin ST; Clark RJ; Klimis H; Christie MJ; Craik DJ; Adams DJ
    Mol Pharmacol; 2007 Dec; 72(6):1406-10. PubMed ID: 17804600
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structure-Activity Studies Reveal the Molecular Basis for GABA
    Sadeghi M; Carstens BB; Callaghan BP; Daniel JT; Tae HS; O'Donnell T; Castro J; Brierley SM; Adams DJ; Craik DJ; Clark RJ
    ACS Chem Biol; 2018 Jun; 13(6):1577-1587. PubMed ID: 29746088
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Interaction of α9α10 Nicotinic Receptors With Peptides and Proteins From Animal Venoms.
    Tsetlin V; Haufe Y; Safronova V; Serov D; Shadamarshan P; Son L; Shelukhina I; Kudryavtsev D; Kryukova E; Kasheverov I; Nicke A; Utkin Y
    Front Cell Neurosci; 2021; 15():765541. PubMed ID: 35002625
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Alpha9 nicotinic acetylcholine receptors and the treatment of pain.
    McIntosh JM; Absalom N; Chebib M; Elgoyhen AB; Vincler M
    Biochem Pharmacol; 2009 Oct; 78(7):693-702. PubMed ID: 19477168
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The Structural Features of α-Conotoxin Specifically Target Different Isoforms of Nicotinic Acetylcholine Receptors.
    Wu RJ; Wang L; Xiang H
    Curr Top Med Chem; 2015; 16(2):156-69. PubMed ID: 26126912
    [TBL] [Abstract][Full Text] [Related]  

  • 34. α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors.
    Wu Y; Zhangsun D; Zhu X; Kaas Q; Zhangsun M; Harvey PJ; Craik DJ; McIntosh JM; Luo S
    J Med Chem; 2017 Jul; 60(13):5826-5833. PubMed ID: 28603989
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.
    Muttenthaler M; Nevin ST; Grishin AA; Ngo ST; Choy PT; Daly NL; Hu SH; Armishaw CJ; Wang CI; Lewis RJ; Martin JL; Noakes PG; Craik DJ; Adams DJ; Alewood PF
    J Am Chem Soc; 2010 Mar; 132(10):3514-22. PubMed ID: 20163143
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
    van Lierop BJ; Robinson SD; Kompella SN; Belgi A; McArthur JR; Hung A; MacRaild CA; Adams DJ; Norton RS; Robinson AJ
    ACS Chem Biol; 2013 Aug; 8(8):1815-21. PubMed ID: 23768016
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mechanism of Action and Structure-Activity Relationship of α-Conotoxin Mr1.1 at the Human α9α10 Nicotinic Acetylcholine Receptor.
    Liang J; Tae HS; Zhao Z; Li X; Zhang J; Chen S; Jiang T; Adams DJ; Yu R
    J Med Chem; 2022 Dec; 65(24):16204-16217. PubMed ID: 36137181
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The α9α10 nicotinic acetylcholine receptors antagonist α-conotoxin RgIA reverses colitis signs in murine dextran sodium sulfate model.
    AlSharari SD; Toma W; Mahmood HM; Michael McIntosh J; Imad Damaj M
    Eur J Pharmacol; 2020 Sep; 883():173320. PubMed ID: 32645334
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs.
    Hone AJ; Kaas Q; Kearns I; Hararah F; Gajewiak J; Christensen S; Craik DJ; McIntosh JM
    J Med Chem; 2021 Feb; 64(3):1685-1700. PubMed ID: 33523678
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Effect of Methionine Oxidation and Substitution of α-Conotoxin TxID on α3β4 Nicotinic Acetylcholine Receptor.
    Ren J; Li R; Ning J; Zhu X; Zhangsun D; Wu Y; Luo S
    Mar Drugs; 2018 Jun; 16(6):. PubMed ID: 29925760
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.