444 related articles for article (PubMed ID: 29743204)
1. ApoE isoforms and carboxyl-terminal-truncated apoE4 forms affect neuronal BACE1 levels and Aβ production independently of their cholesterol efflux capacity.
Dafnis I; Raftopoulou C; Mountaki C; Megalou E; Zannis VI; Chroni A
Biochem J; 2018 May; 475(10):1839-1859. PubMed ID: 29743204
[TBL] [Abstract][Full Text] [Related]
2. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
Hu J; Liu CC; Chen XF; Zhang YW; Xu H; Bu G
Mol Neurodegener; 2015 Mar; 10():6. PubMed ID: 25871773
[TBL] [Abstract][Full Text] [Related]
3. Amyloid-peptide β 42 Enhances the Oligomerization and Neurotoxicity of apoE4: The C-terminal Residues Leu279, Lys282 and Gln284 Modulate the Structural and Functional Properties of apoE4.
Dafnis I; Argyri L; Chroni A
Neuroscience; 2018 Dec; 394():144-155. PubMed ID: 30367942
[TBL] [Abstract][Full Text] [Related]
4. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
[TBL] [Abstract][Full Text] [Related]
5. Membrane-Associated Effects of Glucocorticoid on BACE1 Upregulation and Aβ Generation: Involvement of Lipid Raft-Mediated CREB Activation.
Choi GE; Lee SJ; Lee HJ; Ko SH; Chae CW; Han HJ
J Neurosci; 2017 Aug; 37(35):8459-8476. PubMed ID: 28855330
[TBL] [Abstract][Full Text] [Related]
6. Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons.
Mamada N; Tanokashira D; Hosaka A; Kametani F; Tamaoka A; Araki W
Mol Brain; 2015 Nov; 8(1):73. PubMed ID: 26552445
[TBL] [Abstract][Full Text] [Related]
7. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
8. The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific.
Dafnis I; Argyri L; Sagnou M; Tzinia A; Tsilibary EC; Stratikos E; Chroni A
Sci Rep; 2016 Aug; 6():30654. PubMed ID: 27476701
[TBL] [Abstract][Full Text] [Related]
9. Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Andrew RJ; Fernandez CG; Stanley M; Jiang H; Nguyen P; Rice RC; Buggia-Prévot V; De Rossi P; Vetrivel KS; Lamb R; Argemi A; Allaert ES; Rathbun EM; Krause SV; Wagner SL; Parent AT; Holtzman DM; Thinakaran G
Proc Natl Acad Sci U S A; 2017 Nov; 114(45):E9665-E9674. PubMed ID: 29078331
[TBL] [Abstract][Full Text] [Related]
10. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
[TBL] [Abstract][Full Text] [Related]
11. Plasma ApoE4 Levels Are Lower than ApoE2 and ApoE3 Levels, and Not Associated with Plasma Aβ40/42 Ratio as a Biomarker of Amyloid-β Amyloidosis in Alzheimer's Disease.
Nakamura T; Kawarabayashi T; Ueda T; Shimomura S; Hoshino M; Itoh K; Ihara K; Nakaji S; Takatama M; Ikeda Y; Shoji M
J Alzheimers Dis; 2023; 93(1):333-348. PubMed ID: 36970894
[TBL] [Abstract][Full Text] [Related]
12. Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.
Chen Y; Huang X; Zhang YW; Rockenstein E; Bu G; Golde TE; Masliah E; Xu H
J Neurosci; 2012 Aug; 32(33):11390-5. PubMed ID: 22895721
[TBL] [Abstract][Full Text] [Related]
13. Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target.
Ye S; Huang Y; Müllendorff K; Dong L; Giedt G; Meng EC; Cohen FE; Kuntz ID; Weisgraber KH; Mahley RW
Proc Natl Acad Sci U S A; 2005 Dec; 102(51):18700-5. PubMed ID: 16344478
[TBL] [Abstract][Full Text] [Related]
14. Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease.
Butterfield DA; Mattson MP
Neurobiol Dis; 2020 May; 138():104795. PubMed ID: 32036033
[TBL] [Abstract][Full Text] [Related]
15. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.
Aleshkov S; Abraham CR; Zannis VI
Biochemistry; 1997 Aug; 36(34):10571-80. PubMed ID: 9265639
[TBL] [Abstract][Full Text] [Related]
16. Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.
Marwarha G; Rostad S; Lilek J; Kleinjan M; Schommer J; Ghribi O
J Alzheimers Dis; 2017; 57(3):907-925. PubMed ID: 28304295
[TBL] [Abstract][Full Text] [Related]
17. Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.
Tai LM; Bilousova T; Jungbauer L; Roeske SK; Youmans KL; Yu C; Poon WW; Cornwell LB; Miller CA; Vinters HV; Van Eldik LJ; Fardo DW; Estus S; Bu G; Gylys KH; Ladu MJ
J Biol Chem; 2013 Feb; 288(8):5914-26. PubMed ID: 23293020
[TBL] [Abstract][Full Text] [Related]
18. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.
Panmanee J; Nopparat C; Chavanich N; Shukla M; Mukda S; Song W; Vincent B; Govitrapong P
J Pineal Res; 2015 Oct; 59(3):308-20. PubMed ID: 26123100
[TBL] [Abstract][Full Text] [Related]
19. Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.
Fitz NF; Cronican AA; Saleem M; Fauq AH; Chapman R; Lefterov I; Koldamova R
J Neurosci; 2012 Sep; 32(38):13125-36. PubMed ID: 22993429
[TBL] [Abstract][Full Text] [Related]
20. A combination Alzheimer's therapy targeting BACE1 and neprilysin in 5XFAD transgenic mice.
Devi L; Ohno M
Mol Brain; 2015 Mar; 8():19. PubMed ID: 25884928
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]