181 related articles for article (PubMed ID: 29744674)
1. Phase 1 study of seviteronel, a selective CYP17 lyase and androgen receptor inhibitor, in women with estrogen receptor-positive or triple-negative breast cancer.
Bardia A; Gucalp A; DaCosta N; Gabrail N; Danso M; Ali H; Blackwell KL; Carey LA; Eisner JR; Baskin-Bey ES; Traina TA
Breast Cancer Res Treat; 2018 Aug; 171(1):111-120. PubMed ID: 29744674
[TBL] [Abstract][Full Text] [Related]
2. Phase I Study of Seviteronel, a Selective CYP17 Lyase and Androgen Receptor Inhibitor, in Men with Castration-Resistant Prostate Cancer.
Gupta S; Nordquist LT; Fleming MT; Berry WR; Zhang J; Ervin SL; Eisner JR; Baskin-Bey ES; Shore ND
Clin Cancer Res; 2018 Nov; 24(21):5225-5232. PubMed ID: 30012563
[No Abstract] [Full Text] [Related]
3. A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer.
Peer CJ; Schmidt KT; Kindrick JD; Eisner JR; Brown VV; Baskin-Bey E; Madan R; Figg WD
Cancer Chemother Pharmacol; 2019 Oct; 84(4):759-770. PubMed ID: 31367790
[TBL] [Abstract][Full Text] [Related]
4. Seviteronel, a Novel CYP17 Lyase Inhibitor and Androgen Receptor Antagonist, Radiosensitizes AR-Positive Triple Negative Breast Cancer Cells.
Michmerhuizen AR; Chandler B; Olsen E; Wilder-Romans K; Moubadder L; Liu M; Pesch AM; Zhang A; Ritter C; Ward ST; Santola A; Nyati S; Rae JM; Hayes D; Feng FY; Spratt D; Wahl D; Eisner J; Pierce LJ; Speers C
Front Endocrinol (Lausanne); 2020; 11():35. PubMed ID: 32117061
[TBL] [Abstract][Full Text] [Related]
5. Phase 2 Study of Seviteronel (INO-464) in Patients With Metastatic Castration-Resistant Prostate Cancer After Enzalutamide Treatment.
Madan RA; Schmidt KT; Karzai F; Peer CJ; Cordes LM; Chau CH; Steinberg SM; Owens H; Eisner J; Moore WR; Dahut WL; Gulley JL; Figg WD
Clin Genitourin Cancer; 2020 Aug; 18(4):258-267.e1. PubMed ID: 32327394
[TBL] [Abstract][Full Text] [Related]
6. An open-label, phase 1 study of androgen receptor antagonist, apalutamide in Japanese patients with metastatic castration-resistant prostate cancer.
Tsuchiya T; Imanaka K; Iwaki Y; Oyama R; Hashine K; Yamaguchi A; Uemura H
Int J Clin Oncol; 2019 Dec; 24(12):1596-1604. PubMed ID: 31446511
[TBL] [Abstract][Full Text] [Related]
7. Phase 1b study of orteronel in postmenopausal women with hormone-receptor positive (HR+) metastatic breast cancer.
Rampurwala M; Wisinski KB; Burkard ME; Ehsani S; O'Regan RM; Carmichael L; Kim K; Kolesar J; Tevaarwerk AJ
Invest New Drugs; 2017 Feb; 35(1):87-94. PubMed ID: 27826831
[TBL] [Abstract][Full Text] [Related]
8. ODM-204, a Novel Dual Inhibitor of CYP17A1 and Androgen Receptor: Early Results from Phase I Dose Escalation in Men with Castration-resistant Prostate Cancer.
Peltola KJ; Bono P; Jones RH; Vjaters E; Nykänen P; Vuorela A; Oksala R; Pohjanjousi P; Mustonen MVJ; Fizazi K; Massard C
Eur Urol Focus; 2020 Jan; 6(1):63-70. PubMed ID: 30194031
[TBL] [Abstract][Full Text] [Related]
9. TBCRC 032 IB/II Multicenter Study: Molecular Insights to AR Antagonist and PI3K Inhibitor Efficacy in Patients with AR
Lehmann BD; Abramson VG; Sanders ME; Mayer EL; Haddad TC; Nanda R; Van Poznak C; Storniolo AM; Nangia JR; Gonzalez-Ericsson PI; Sanchez V; Johnson KN; Abramson RG; Chen SC; Shyr Y; Arteaga CL; Wolff AC; Pietenpol JA;
Clin Cancer Res; 2020 May; 26(9):2111-2123. PubMed ID: 31822498
[TBL] [Abstract][Full Text] [Related]
10. Targeting the androgen receptor in triple-negative breast cancer.
Gucalp A; Traina TA
Curr Probl Cancer; 2016; 40(2-4):141-150. PubMed ID: 27816190
[TBL] [Abstract][Full Text] [Related]
11. A First-in-Human Study of the New Oral Selective Estrogen Receptor Degrader AZD9496 for ER
Hamilton EP; Patel MR; Armstrong AC; Baird RD; Jhaveri K; Hoch M; Klinowska T; Lindemann JPO; Morgan SR; Schiavon G; Weir HM; Im SA
Clin Cancer Res; 2018 Aug; 24(15):3510-3518. PubMed ID: 29440181
[No Abstract] [Full Text] [Related]
12. The hunt for a selective 17,20 lyase inhibitor; learning lessons from nature.
Bird IM; Abbott DH
J Steroid Biochem Mol Biol; 2016 Oct; 163():136-46. PubMed ID: 27154414
[TBL] [Abstract][Full Text] [Related]
13. Phase 1 study of oral selective estrogen receptor degrader (SERD) amcenestrant (SAR439859), in Japanese women with ER-positive and HER2-negative advanced breast cancer (AMEERA-2).
Tamura K; Mukohara T; Yonemori K; Kawabata Y; Nicolas X; Tanaka T; Iwata H
Breast Cancer; 2023 May; 30(3):506-517. PubMed ID: 36977973
[TBL] [Abstract][Full Text] [Related]
14. AZD3514, an oral selective androgen receptor down-regulator in patients with castration-resistant prostate cancer - results of two parallel first-in-human phase I studies.
Omlin A; Jones RJ; van der Noll R; Satoh T; Niwakawa M; Smith SA; Graham J; Ong M; Finkelman RD; Schellens JH; Zivi A; Crespo M; Riisnaes R; Nava-Rodrigues D; Malone MD; Dive C; Sloane R; Moore D; Alumkal JJ; Dymond A; Dickinson PA; Ranson M; Clack G; de Bono J; Elliott T
Invest New Drugs; 2015 Jun; 33(3):679-90. PubMed ID: 25920479
[TBL] [Abstract][Full Text] [Related]
15. A phase 1 study to assess the safety, pharmacokinetics, and anti-tumor activity of the androgen receptor n-terminal domain inhibitor epi-506 in patients with metastatic castration-resistant prostate cancer.
Maurice-Dror C; Le Moigne R; Vaishampayan U; Montgomery RB; Gordon MS; Hong NH; DiMascio L; Perabo F; Chi KN
Invest New Drugs; 2022 Apr; 40(2):322-329. PubMed ID: 34843005
[TBL] [Abstract][Full Text] [Related]
16. Activity of Combined Androgen Receptor Antagonism and Cell Cycle Inhibition in Androgen Receptor Positive Triple Negative Breast Cancer.
Christenson JL; O'Neill KI; Williams MM; Spoelstra NS; Jones KL; Trahan GD; Reese J; Van Patten ET; Elias A; Eisner JR; Richer JK
Mol Cancer Ther; 2021 Jun; 20(6):1062-1071. PubMed ID: 33722849
[TBL] [Abstract][Full Text] [Related]
17. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+/HER2- Metastatic Breast Cancer.
LoRusso P; Hamilton E; Ma C; Vidula N; Bagley RG; Troy S; Annett M; Yu Z; Conlan MG; Weise A
Clin Breast Cancer; 2022 Jan; 22(1):67-77. PubMed ID: 34565686
[TBL] [Abstract][Full Text] [Related]
18. Phase II Study of Dehydroepiandrosterone in Androgen Receptor-Positive Metastatic Breast Cancer.
Pietri E; Massa I; Bravaccini S; Ravaioli S; Tumedei MM; Petracci E; Donati C; Schirone A; Piacentini F; Gianni L; Nicolini M; Campadelli E; Gennari A; Saba A; Campi B; Valmorri L; Andreis D; Fabbri F; Amadori D; Rocca A
Oncologist; 2019 Jun; 24(6):743-e205. PubMed ID: 30591548
[TBL] [Abstract][Full Text] [Related]
19. Activity and safety of ODM-201 in patients with progressive metastatic castration-resistant prostate cancer (ARADES): an open-label phase 1 dose-escalation and randomised phase 2 dose expansion trial.
Fizazi K; Massard C; Bono P; Jones R; Kataja V; James N; Garcia JA; Protheroe A; Tammela TL; Elliott T; Mattila L; Aspegren J; Vuorela A; Langmuir P; Mustonen M;
Lancet Oncol; 2014 Aug; 15(9):975-85. PubMed ID: 24974051
[TBL] [Abstract][Full Text] [Related]
20. A phase Ib study of sonidegib (LDE225), an oral small molecule inhibitor of smoothened or Hedgehog pathway, in combination with docetaxel in triple negative advanced breast cancer patients: GEICAM/2012-12 (EDALINE) study.
Ruiz-Borrego M; Jimenez B; Antolín S; García-Saenz JA; Corral J; Jerez Y; Trigo J; Urruticoechea A; Colom H; Gonzalo N; Muñoz C; Benito S; Caballero R; Bezares S; Carrasco E; Rojo F; Martín M
Invest New Drugs; 2019 Feb; 37(1):98-108. PubMed ID: 29948356
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
