BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 29746127)

  • 1. Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis.
    Akgul O; Di Cesare Mannelli L; Vullo D; Angeli A; Ghelardini C; Bartolucci G; Alfawaz Altamimi AS; Scozzafava A; Supuran CT; Carta F
    J Med Chem; 2018 Jun; 61(11):4961-4977. PubMed ID: 29746127
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis.
    Bua S; Di Cesare Mannelli L; Vullo D; Ghelardini C; Bartolucci G; Scozzafava A; Supuran CT; Carta F
    J Med Chem; 2017 Feb; 60(3):1159-1170. PubMed ID: 28075587
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis.
    Bua S; Lucarini L; Micheli L; Menicatti M; Bartolucci G; Selleri S; Di Cesare Mannelli L; Ghelardini C; Masini E; Carta F; Gratteri P; Nocentini A; Supuran CT
    J Med Chem; 2020 Mar; 63(5):2325-2342. PubMed ID: 31689108
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal.
    Mishra CB; Kumari S; Angeli A; Bua S; Buonanno M; Monti SM; Tiwari M; Supuran CT
    Eur J Med Chem; 2018 Aug; 156():430-443. PubMed ID: 30015076
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors.
    La Regina G; Coluccia A; Famiglini V; Pelliccia S; Monti L; Vullo D; Nuti E; Alterio V; De Simone G; Monti SM; Pan P; Parkkila S; Supuran CT; Rossello A; Silvestri R
    J Med Chem; 2015 Nov; 58(21):8564-72. PubMed ID: 26497049
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis.
    Micheli L; Bozdag M; Akgul O; Carta F; Guccione C; Bergonzi MC; Bilia AR; Cinci L; Lucarini E; Parisio C; Supuran CT; Ghelardini C; Di Cesare Mannelli L
    Int J Mol Sci; 2019 Apr; 20(8):. PubMed ID: 31003542
    [No Abstract]   [Full Text] [Related]  

  • 7. Dual Cyclooxygenase and Carbonic Anhydrase Inhibition by Nonsteroidal Anti-Inflammatory Drugs for the Treatment of Cancer.
    De Monte C; Carradori S; Gentili A; Mollica A; Trisciuoglio D; Supuran CT
    Curr Med Chem; 2015; 22(24):2812-8. PubMed ID: 26180003
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of curcumin inspired sulfonamide derivatives as a new class of carbonic anhydrase isoforms I, II, IX, and XII inhibitors.
    Ramya PVS; Angapelly S; Angeli A; Digwal CS; Arifuddin M; Babu BN; Supuran CT; Kamal A
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):1274-1281. PubMed ID: 28965419
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New series of sulfonamides containing amino acid moiety act as effective and selective inhibitors of tumor-associated carbonic anhydrase XII.
    Ceruso M; Bragagni M; AlOthman Z; Osman SM; Supuran CT
    J Enzyme Inhib Med Chem; 2015 Jun; 30(3):430-4. PubMed ID: 25089707
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of a new series of N⁴-substituted 4-(2-aminoethyl)benzenesulfonamides and their inhibitory effect on human carbonic anhydrase cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII.
    Sławiński J; Brzozowski Z; Żołnowska B; Szafrański K; Pogorzelska A; Vullo D; Supuran CT
    Eur J Med Chem; 2014 Sep; 84():59-67. PubMed ID: 25016228
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.
    Sławiński J; Pogorzelska A; Żołnowska B; Brożewicz K; Vullo D; Supuran CT
    Eur J Med Chem; 2014 Jul; 82():47-55. PubMed ID: 24871996
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors.
    Rosatelli E; Carotti A; Ceruso M; Supuran CT; Gioiello A
    Bioorg Med Chem Lett; 2014 Aug; 24(15):3422-5. PubMed ID: 24948563
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors.
    Angapelly S; Ramya PVS; Angeli A; Del Prete S; Capasso C; Arifuddin M; Supuran CT
    Bioorg Med Chem; 2017 Oct; 25(20):5726-5732. PubMed ID: 28887000
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity.
    Congiu C; Onnis V; Deplano A; Balboni G; Dedeoglu N; Supuran CT
    Bioorg Med Chem Lett; 2015 Sep; 25(18):3850-3. PubMed ID: 26233435
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms.
    Krasavin M; Korsakov M; Dorogov M; Tuccinardi T; Dedeoglu N; Supuran CT
    Eur J Med Chem; 2015 Aug; 101():334-47. PubMed ID: 26160114
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of novel aromatic and heterocyclic bis-sulfonamide Schiff bases as carbonic anhydrase I, II, VII and IX inhibitors.
    Akocak S; Lolak N; Nocentini A; Karakoc G; Tufan A; Supuran CT
    Bioorg Med Chem; 2017 Jun; 25(12):3093-3097. PubMed ID: 28400084
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII.
    Eldehna WM; Fares M; Ceruso M; Ghabbour HA; Abou-Seri SM; Abdel-Aziz HA; Abou El Ella DA; Supuran CT
    Eur J Med Chem; 2016 Mar; 110():259-66. PubMed ID: 26840366
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties.
    Ghorab MM; Alsaid MS; Ceruso M; Nissan YM; Supuran CT
    Bioorg Med Chem; 2014 Jul; 22(14):3684-95. PubMed ID: 24878360
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.
    Rami M; Maresca A; Smaine FZ; Montero JL; Scozzafava A; Winum JY; Supuran CT
    Bioorg Med Chem Lett; 2011 May; 21(10):2975-9. PubMed ID: 21470859
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action.
    Bragagni M; Carta F; Osman SM; AlOthman Z; Supuran CT
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):701-706. PubMed ID: 28335646
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.