BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 29748115)

  • 1. KRAS Activating Signaling Triggers Arteriovenous Malformations.
    Cheng F; Nussinov R
    Trends Biochem Sci; 2018 Jul; 43(7):481-483. PubMed ID: 29748115
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain.
    Nikolaev SI; Vetiska S; Bonilla X; Boudreau E; Jauhiainen S; Rezai Jahromi B; Khyzha N; DiStefano PV; Suutarinen S; Kiehl TR; Mendes Pereira V; Herman AM; Krings T; Andrade-Barazarte H; Tung T; Valiante T; Zadeh G; Tymianski M; Rauramaa T; Ylä-Herttuala S; Wythe JD; Antonarakis SE; Frösen J; Fish JE; Radovanovic I
    N Engl J Med; 2018 Jan; 378(3):250-261. PubMed ID: 29298116
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Somatic Gain of KRAS Function in the Endothelium Is Sufficient to Cause Vascular Malformations That Require MEK but Not PI3K Signaling.
    Fish JE; Flores Suarez CP; Boudreau E; Herman AM; Gutierrez MC; Gustafson D; DiStefano PV; Cui M; Chen Z; De Ruiz KB; Schexnayder TS; Ward CS; Radovanovic I; Wythe JD
    Circ Res; 2020 Aug; 127(6):727-743. PubMed ID: 32552404
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High prevalence of KRAS/BRAF somatic mutations in brain and spinal cord arteriovenous malformations.
    Hong T; Yan Y; Li J; Radovanovic I; Ma X; Shao YW; Yu J; Ma Y; Zhang P; Ling F; Huang S; Zhang H; Wang Y
    Brain; 2019 Jan; 142(1):23-34. PubMed ID: 30544177
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Somatic mosaicism in the MAPK pathway in sporadic brain arteriovenous malformation and association with phenotype.
    Gao S; Nelson J; Weinsheimer S; Winkler EA; Rutledge C; Abla AA; Gupta N; Shieh JT; Cooke DL; Hetts SW; Tihan T; Hess CP; Ko N; Walcott BP; McCulloch CE; Lawton MT; Su H; Pawlikowska L; Kim H
    J Neurosurg; 2022 Jan; 136(1):148-155. PubMed ID: 34214981
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain.
    Nikolaev SI; Fish JE; Radovanovic I
    N Engl J Med; 2018 Apr; 378(16):1561-1562. PubMed ID: 29669234
    [No Abstract]   [Full Text] [Related]  

  • 7. Selective Endothelial Hyperactivation of Oncogenic KRAS Induces Brain Arteriovenous Malformations in Mice.
    Park ES; Kim S; Huang S; Yoo JY; Körbelin J; Lee TJ; Kaur B; Dash PK; Chen PR; Kim E
    Ann Neurol; 2021 May; 89(5):926-941. PubMed ID: 33675084
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Epidermal Growth Factor Receptor Signaling to the Mitogen Activated Protein Kinase Pathway Bypasses Ras in Pancreatic Cancer Cells.
    Lee S; Heinrich EL; Lu J; Lee W; Choi AH; Luu C; Chung V; Fakih M; Kim J
    Pancreas; 2016 Feb; 45(2):286-92. PubMed ID: 26262587
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the RAS/RAF/ERK signaling pathway contributes to resistance to sunitinib in thyroid carcinoma cell lines.
    Piscazzi A; Costantino E; Maddalena F; Natalicchio MI; Gerardi AM; Antonetti R; Cignarelli M; Landriscina M
    J Clin Endocrinol Metab; 2012 Jun; 97(6):E898-906. PubMed ID: 22442268
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.
    Ji H; Wang Z; Perera SA; Li D; Liang MC; Zaghlul S; McNamara K; Chen L; Albert M; Sun Y; Al-Hashem R; Chirieac LR; Padera R; Bronson RT; Thomas RK; Garraway LA; Jänne PA; Johnson BE; Chin L; Wong KK
    Cancer Res; 2007 May; 67(10):4933-9. PubMed ID: 17510423
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain.
    Morita H; Komuro I
    N Engl J Med; 2018 Apr; 378(16):1561. PubMed ID: 29671469
    [No Abstract]   [Full Text] [Related]  

  • 12. The comparison between dual inhibition of mTOR with MAPK and PI3K signaling pathways in KRAS mutant NSCLC cell lines.
    Dogan Turacli I; Ozkan AC; Ekmekci A
    Tumour Biol; 2015 Dec; 36(12):9339-45. PubMed ID: 26108998
    [TBL] [Abstract][Full Text] [Related]  

  • 13. KRAS G12D or G12V Mutation in Human Brain Arteriovenous Malformations.
    Oka M; Kushamae M; Aoki T; Yamaguchi T; Kitazato K; Abekura Y; Kawamata T; Mizutani T; Miyamoto S; Takagi Y
    World Neurosurg; 2019 Jun; 126():e1365-e1373. PubMed ID: 30902772
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Review of treatment and therapeutic targets in brain arteriovenous malformation.
    Pan P; Weinsheimer S; Cooke D; Winkler E; Abla A; Kim H; Su H
    J Cereb Blood Flow Metab; 2021 Dec; 41(12):3141-3156. PubMed ID: 34162280
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endothelial MAP2K1 mutations in arteriovenous malformation activate the RAS/MAPK pathway.
    Smits PJ; Konczyk DJ; Sudduth CL; Goss JA; Greene AK
    Biochem Biophys Res Commun; 2020 Aug; 529(2):450-454. PubMed ID: 32703450
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation.
    Lionetti M; Barbieri M; Todoerti K; Agnelli L; Marzorati S; Fabris S; Ciceri G; Galletti S; Milesi G; Manzoni M; Mazzoni M; Greco A; Tonon G; Musto P; Baldini L; Neri A
    Oncotarget; 2015 Sep; 6(27):24205-17. PubMed ID: 26090869
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling.
    Kiel C; Serrano L
    Sci Signal; 2009 Jul; 2(81):ra38. PubMed ID: 19638615
    [TBL] [Abstract][Full Text] [Related]  

  • 18. KRAS/BRAF mutations in brain arteriovenous malformations: A systematic review and meta-analysis.
    Bameri O; Salarzaei M; Parooie F
    Interv Neuroradiol; 2021 Aug; 27(4):539-546. PubMed ID: 33401991
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RAS/MAPK pathway hyperactivation determines poor prognosis in undifferentiated pleomorphic sarcomas.
    Serrano C; Romagosa C; Hernández-Losa J; Simonetti S; Valverde C; Moliné T; Somoza R; Pérez M; Vélez R; Vergés R; Domínguez R; Carles J; Ramón Y Cajal S
    Cancer; 2016 Jan; 122(1):99-107. PubMed ID: 26479291
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oncogenic Effects of High MAPK Activity in Colorectal Cancer Mark Progenitor Cells and Persist Irrespective of RAS Mutations.
    Blaj C; Schmidt EM; Lamprecht S; Hermeking H; Jung A; Kirchner T; Horst D
    Cancer Res; 2017 Apr; 77(7):1763-1774. PubMed ID: 28202525
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.