BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 29748250)

  • 1. Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung.
    Tagalakis AD; Munye MM; Ivanova R; Chen H; Smith CM; Aldossary AM; Rosa LZ; Moulding D; Barnes JL; Kafetzis KN; Jones SA; Baines DL; Moss GWJ; O'Callaghan C; McAnulty RJ; Hart SL
    Thorax; 2018 Sep; 73(9):847-856. PubMed ID: 29748250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis.
    Manunta MDI; Tagalakis AD; Attwood M; Aldossary AM; Barnes JL; Munye MM; Weng A; McAnulty RJ; Hart SL
    Sci Rep; 2017 Apr; 7(1):700. PubMed ID: 28386087
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ursodeoxycholic acid inhibits ENaC and Na/K pump activity to restore airway surface liquid height in cystic fibrosis bronchial epithelial cells.
    Mroz MS; Harvey BJ
    Steroids; 2019 Nov; 151():108461. PubMed ID: 31344409
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Epithelial sodium channel inhibition in primary human bronchial epithelia by transfected siRNA.
    Caci E; Melani R; Pedemonte N; Yueksekdag G; Ravazzolo R; Rosenecker J; Galietta LJ; Zegarra-Moran O
    Am J Respir Cell Mol Biol; 2009 Feb; 40(2):211-6. PubMed ID: 18723440
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SPX-101 Is a Novel Epithelial Sodium Channel-targeted Therapeutic for Cystic Fibrosis That Restores Mucus Transport.
    Scott DW; Walker MP; Sesma J; Wu B; Stuhlmiller TJ; Sabater JR; Abraham WM; Crowder TM; Christensen DJ; Tarran R
    Am J Respir Crit Care Med; 2017 Sep; 196(6):734-744. PubMed ID: 28481660
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The epithelial sodium channel (ENaC) as a therapeutic target for cystic fibrosis lung disease.
    Moore PJ; Tarran R
    Expert Opin Ther Targets; 2018 Aug; 22(8):687-701. PubMed ID: 30028216
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Epithelial sodium channel silencing as a strategy to correct the airway surface fluid deficit in cystic fibrosis.
    Gianotti A; Melani R; Caci E; Sondo E; Ravazzolo R; Galietta LJ; Zegarra-Moran O
    Am J Respir Cell Mol Biol; 2013 Sep; 49(3):445-52. PubMed ID: 23600628
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effect of ambroxol on chloride transport, CFTR and ENaC in cystic fibrosis airway epithelial cells.
    Varelogianni G; Hussain R; Strid H; Oliynyk I; Roomans GM; Johannesson M
    Cell Biol Int; 2013 Nov; 37(11):1149-56. PubMed ID: 23765701
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ENaC inhibitors and airway re-hydration in cystic fibrosis: state of the art.
    Althaus M
    Curr Mol Pharmacol; 2013 Mar; 6(1):3-12. PubMed ID: 23547930
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of the amiloride-sensitive epithelial Na+ channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease.
    Mall MA
    Exp Physiol; 2009 Feb; 94(2):171-4. PubMed ID: 19060118
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Engineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis-based cell and mice models.
    Mukherjee A; MacDonald KD; Kim J; Henderson MI; Eygeris Y; Sahay G
    Sci Adv; 2020 Nov; 6(47):. PubMed ID: 33208364
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo.
    Griesenbach U; Kitson C; Escudero Garcia S; Farley R; Singh C; Somerton L; Painter H; Smith RL; Gill DR; Hyde SC; Chow YH; Hu J; Gray M; Edbrooke M; Ogilvie V; MacGregor G; Scheule RK; Cheng SH; Caplen NJ; Alton EW
    Respir Res; 2006 Feb; 7(1):26. PubMed ID: 16480492
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting ENaC as a Molecular Suspect in Cystic Fibrosis.
    Bangel-Ruland N; Tomczak K; Weber WM
    Curr Drug Targets; 2015; 16(9):951-7. PubMed ID: 25544019
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epithelial Na
    Smith NJ; Solovay CF
    Pharm Pat Anal; 2017 Jul; 6(4):179-188. PubMed ID: 28696180
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
    Garland AL; Walton WG; Coakley RD; Tan CD; Gilmore RC; Hobbs CA; Tripathy A; Clunes LA; Bencharit S; Stutts MJ; Betts L; Redinbo MR; Tarran R
    Proc Natl Acad Sci U S A; 2013 Oct; 110(40):15973-8. PubMed ID: 24043776
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The epithelial sodium channel (ENaC) as a therapeutic target for cystic fibrosis.
    Shei RJ; Peabody JE; Kaza N; Rowe SM
    Curr Opin Pharmacol; 2018 Dec; 43():152-165. PubMed ID: 30340955
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of pediatric cystic fibrosis airway epithelial cell cultures at the air-liquid interface obtained by non-invasive nasal cytology brush sampling.
    Schögler A; Blank F; Brügger M; Beyeler S; Tschanz SA; Regamey N; Casaulta C; Geiser T; Alves MP
    Respir Res; 2017 Dec; 18(1):215. PubMed ID: 29282053
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antisense oligonucleotide targeting of mRNAs encoding ENaC subunits α, β, and γ improves cystic fibrosis-like disease in mice.
    Zhao C; Crosby J; Lv T; Bai D; Monia BP; Guo S
    J Cyst Fibros; 2019 May; 18(3):334-341. PubMed ID: 30100257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways.
    Reihill JA; Walker B; Hamilton RA; Ferguson TE; Elborn JS; Stutts MJ; Harvey BJ; Saint-Criq V; Hendrick SM; Martin SL
    Am J Respir Crit Care Med; 2016 Sep; 194(6):701-10. PubMed ID: 27014936
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Linking increased airway hydration, ciliary beating, and mucociliary clearance through ENaC inhibition.
    Åstrand AB; Hemmerling M; Root J; Wingren C; Pesic J; Johansson E; Garland AL; Ghosh A; Tarran R
    Am J Physiol Lung Cell Mol Physiol; 2015 Jan; 308(1):L22-32. PubMed ID: 25361567
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.