BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 29749536)

  • 1. BIIB021, an Hsp90 inhibitor: A promising therapeutic strategy for blood malignancies (Review).
    He W; Hu H
    Oncol Rep; 2018 Jul; 40(1):3-15. PubMed ID: 29749536
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90.
    Lundgren K; Zhang H; Brekken J; Huser N; Powell RE; Timple N; Busch DJ; Neely L; Sensintaffar JL; Yang YC; McKenzie A; Friedman J; Scannevin R; Kamal A; Hong K; Kasibhatla SR; Boehm MF; Burrows FJ
    Mol Cancer Ther; 2009 Apr; 8(4):921-9. PubMed ID: 19372565
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BIIB021: A novel inhibitor to heat shock protein 90-addicted oncology.
    Yan L; Zhang W; Zhang B; Xuan C; Wang D
    Tumour Biol; 2017 Apr; 39(4):1010428317698355. PubMed ID: 28443462
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells.
    He W; Ye X; Huang X; Lel W; You L; Wang L; Chen X; Qian W
    Int J Oncol; 2016 Apr; 48(4):1710-20. PubMed ID: 26892093
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BIIB021, a synthetic Hsp90 inhibitor, has broad application against tumors with acquired multidrug resistance.
    Zhang H; Neely L; Lundgren K; Yang YC; Lough R; Timple N; Burrows F
    Int J Cancer; 2010 Mar; 126(5):1226-34. PubMed ID: 19676042
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BIIB021, a novel Hsp90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy.
    Yin X; Zhang H; Lundgren K; Wilson L; Burrows F; Shores CG
    Int J Cancer; 2010 Mar; 126(5):1216-25. PubMed ID: 19662650
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BIIB021, a novel Hsp90 inhibitor, sensitizes esophageal squamous cell carcinoma to radiation.
    Wang XT; Bao CH; Jia YB; Wang N; Ma W; Liu F; Wang C; Wang JB; Song QX; Cheng YF
    Biochem Biophys Res Commun; 2014 Oct; 452(4):945-50. PubMed ID: 25223594
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated primary effusion lymphoma and blocks vFLIP K13-induced NF-κB.
    Gopalakrishnan R; Matta H; Chaudhary PM
    Clin Cancer Res; 2013 Sep; 19(18):5016-26. PubMed ID: 23881928
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hsp90 inhibitor BIIB021 enhances triptolide-induced apoptosis of human T-cell acute lymphoblastic leukemia cells in vitro mainly by disrupting p53-MDM2 balance.
    Li M; Zhang X; Zhou WJ; Chen YH; Liu H; Liu L; Yang CM; Qan WB
    Acta Pharmacol Sin; 2013 Dec; 34(12):1545-53. PubMed ID: 24241349
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heat shock protein 90 inhibitor BIIB021 (CNF2024) depletes NF-kappaB and sensitizes Hodgkin's lymphoma cells for natural killer cell-mediated cytotoxicity.
    Böll B; Eltaib F; Reiners KS; von Tresckow B; Tawadros S; Simhadri VR; Burrows FJ; Lundgren K; Hansen HP; Engert A; von Strandmann EP
    Clin Cancer Res; 2009 Aug; 15(16):5108-16. PubMed ID: 19671844
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A phase 1, dose-escalation, pharmacokinetic and pharmacodynamic study of BIIB021 administered orally in patients with advanced solid tumors.
    Saif MW; Takimoto C; Mita M; Banerji U; Lamanna N; Castro J; O'Brien S; Stogard C; Von Hoff D
    Clin Cancer Res; 2014 Jan; 20(2):445-55. PubMed ID: 24097863
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heat shock protein 90 inhibitors induce functional inhibition of human natural killer cells in a dose-dependent manner.
    Huyan T; Li Q; Dong DD; Yang H; Zhang J; Huang QS; Yin DC; Shang P
    Immunopharmacol Immunotoxicol; 2016; 38(2):77-86. PubMed ID: 26642940
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phase II study of the HSP90-inhibitor BIIB021 in gastrointestinal stromal tumors.
    Dickson MA; Okuno SH; Keohan ML; Maki RG; D'Adamo DR; Akhurst TJ; Antonescu CR; Schwartz GK
    Ann Oncol; 2013 Jan; 24(1):252-7. PubMed ID: 22898035
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells.
    Kim SH; Cho YK; Huh JH; Kang JG; Ihm SH; Choi MG; Lee SJ
    Anticancer Res; 2020 Nov; 40(11):6137-6150. PubMed ID: 33109551
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synergistic cytotoxicity of BIIB021 with triptolide through suppression of PI3K/Akt/mTOR and NF-κB signal pathways in thyroid carcinoma cells.
    Kim SH; Kang JG; Kim CS; Ihm SH; Choi MG; Yoo HJ; Lee SJ
    Biomed Pharmacother; 2016 Oct; 83():22-32. PubMed ID: 27470546
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90.
    Shin SC; El-Damasy AK; Lee JH; Seo SH; Kim JH; Seo YH; Lee Y; Yu JH; Bang EK; Kim EE; Keum G
    Int J Mol Sci; 2020 Dec; 21(24):. PubMed ID: 33317068
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1.
    Ding Y; Adachi H; Katsuno M; Sahashi K; Kondo N; Iida M; Tohnai G; Nakatsuji H; Sobue G
    Neuroscience; 2016 Jul; 327():20-31. PubMed ID: 27058144
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hsp90 inhibition in adrenocortical carcinoma: Limited drug synergism with mitotane.
    Sbiera S; Kendl S; Weigand I; Sbiera I; Fassnacht M; Kroiss M
    Mol Cell Endocrinol; 2019 Jan; 480():36-41. PubMed ID: 30315857
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BIIB021, an orally available and small-molecule inhibitor of HSP90, activates intrinsic apoptotic pathway in human cervical adenocarcinoma cell line (HeLa).
    Güven CM; Özgür A
    Eur Rev Med Pharmacol Sci; 2023 Aug; 27(15):7299-7308. PubMed ID: 37606138
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heat-shock protein 90 (Hsp90) as a molecular target for therapy of gastrointestinal cancer.
    Moser C; Lang SA; Stoeltzing O
    Anticancer Res; 2009 Jun; 29(6):2031-42. PubMed ID: 19528462
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.