These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 29753878)

  • 1. Targeting HIF-2α as therapy for advanced cancers.
    Murugesan T; Rajajeyabalachandran G; Kumar S; Nagaraju S; Jegatheesan SK
    Drug Discov Today; 2018 Jul; 23(7):1444-1451. PubMed ID: 29753878
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypoxia-mediated drug resistance: novel insights on the functional interaction of HIFs and cell death pathways.
    Rohwer N; Cramer T
    Drug Resist Updat; 2011 Jun; 14(3):191-201. PubMed ID: 21466972
    [TBL] [Abstract][Full Text] [Related]  

  • 3. c-Myc is regulated by HIF-2α in chronic hypoxia and influences sensitivity to 5-FU in colon cancer.
    Wang L; Xue M; Chung DC
    Oncotarget; 2016 Nov; 7(48):78910-78917. PubMed ID: 27793037
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HIF-2alpha: Achilles' heel of pseudohypoxic subtype paraganglioma and other related conditions.
    Tella SH; Taïeb D; Pacak K
    Eur J Cancer; 2017 Nov; 86():1-4. PubMed ID: 28946040
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Upregulation of HIF-2α induced by sorafenib contributes to the resistance by activating the TGF-α/EGFR pathway in hepatocellular carcinoma cells.
    Zhao D; Zhai B; He C; Tan G; Jiang X; Pan S; Dong X; Wei Z; Ma L; Qiao H; Jiang H; Sun X
    Cell Signal; 2014 May; 26(5):1030-9. PubMed ID: 24486412
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recent progress in the development of hypoxia-inducible factor 2α (HIF-2α) modulators: Inhibitors, agonists, and degraders (2009-2024).
    Cheng B; Ma X; Zhou Y; Liu J; Fei X; Pan W; Peng X; Wang W; Chen J
    Eur J Med Chem; 2024 Sep; 275():116645. PubMed ID: 38959730
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Comprehensive Description of Hypoxia-inducible Factor 2α Inhibitors as Anticancer Agents: A Mini-review.
    Lu H; Zhu Y; Liu W; Yan Y; Jiang X; Wang Q; Zhao Y; He M; Wei M
    Curr Med Chem; 2023; 30(25):2835-2849. PubMed ID: 36043744
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The transcriptional factors HIF-1 and HIF-2 and their novel inhibitors in cancer therapy.
    Albadari N; Deng S; Li W
    Expert Opin Drug Discov; 2019 Jul; 14(7):667-682. PubMed ID: 31070059
    [No Abstract]   [Full Text] [Related]  

  • 9. Current insights and future perspectives of hypoxia-inducible factor-targeted therapy in cancer.
    Ajith TA
    J Basic Clin Physiol Pharmacol; 2018 Dec; 30(1):11-18. PubMed ID: 30260792
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiplicity of hypoxia-inducible transcription factors and their connection to the circadian clock in the zebrafish.
    Pelster B; Egg M
    Physiol Biochem Zool; 2015; 88(2):146-57. PubMed ID: 25730270
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses.
    Yoon H; Shin SH; Shin DH; Chun YS; Park JW
    Biochem Biophys Res Commun; 2014 Jan; 444(1):36-43. PubMed ID: 24423936
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells.
    Nauta TD; Duyndam MC; Weijers EM; van Hinsbergh VM; Koolwijk P
    PLoS One; 2016; 11(8):e0160700. PubMed ID: 27490118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of hypoxia-inducible factor-1α and -2α in androgen insensitive prostate cancer cells.
    Jeong CW; Yoon CY; Jeong SJ; Hong SK; Byun SS; Kwak C; Lee SE
    Urol Oncol; 2013 Nov; 31(8):1448-56. PubMed ID: 22537539
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased activation of the hypoxia-inducible factor pathway in varicose veins.
    Lim CS; Kiriakidis S; Paleolog EM; Davies AH
    J Vasc Surg; 2012 May; 55(5):1427-39. PubMed ID: 22277691
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A patent review on hypoxia-inducible factor (HIF) modulators (2021-2023).
    Liu J; Gao Y; Zhang X
    Expert Opin Ther Pat; 2024 Aug; 34(8):651-664. PubMed ID: 38874005
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIF-1alpha and -2alpha genes in a hypoxia-sensitive teleost species Megalobrama amblycephala: cDNA cloning, expression and different responses to hypoxia.
    Shen RJ; Jiang XY; Pu JW; Zou SM
    Comp Biochem Physiol B Biochem Mol Biol; 2010 Nov; 157(3):273-80. PubMed ID: 20615476
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Developmental Expression and Hypoxic Induction of Hypoxia Inducible Transcription Factors in the Zebrafish.
    Köblitz L; Fiechtner B; Baus K; Lussnig R; Pelster B
    PLoS One; 2015; 10(6):e0128938. PubMed ID: 26052946
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA; Ashcroft M
    Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate ( S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1 H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385).
    Wehn PM; Rizzi JP; Dixon DD; Grina JA; Schlachter ST; Wang B; Xu R; Yang H; Du X; Han G; Wang K; Cao Z; Cheng T; Czerwinski RM; Goggin BS; Huang H; Halfmann MM; Maddie MA; Morton EL; Olive SR; Tan H; Xie S; Wong T; Josey JA; Wallace EM
    J Med Chem; 2018 Nov; 61(21):9691-9721. PubMed ID: 30289716
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small-molecule inhibitors of the HIF pathway and synthetic lethal interactions.
    Jones DT; Harris AL
    Expert Opin Ther Targets; 2012 May; 16(5):463-80. PubMed ID: 22512262
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.