BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 29755956)

  • 1. Preleukemia and Leukemia-Initiating Cell Activity in inv(16) Acute Myeloid Leukemia.
    Pulikkan JA; Castilla LH
    Front Oncol; 2018; 8():129. PubMed ID: 29755956
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis.
    Xue L; Pulikkan JA; Valk PJ; Castilla LH
    Blood; 2014 Jul; 124(3):426-36. PubMed ID: 24894773
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular Basis and Targeted Inhibition of CBFβ-SMMHC Acute Myeloid Leukemia.
    Castilla LH; Bushweller JH
    Adv Exp Med Biol; 2017; 962():229-244. PubMed ID: 28299661
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HDAC1 Is a Required Cofactor of CBFβ-SMMHC and a Potential Therapeutic Target in Inversion 16 Acute Myeloid Leukemia.
    Richter LE; Wang Y; Becker ME; Coburn RA; Williams JT; Amador C; Hyde RK
    Mol Cancer Res; 2019 Jun; 17(6):1241-1252. PubMed ID: 30814129
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development.
    Zhen T; Cao Y; Ren G; Zhao L; Hyde RK; Lopez G; Feng D; Alemu L; Zhao K; Liu PP
    Blood; 2020 Nov; 136(21):2373-2385. PubMed ID: 32929473
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia.
    Richter L; Wang Y; Hyde RK
    Oncotarget; 2016 Oct; 7(40):66255-66266. PubMed ID: 27542261
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Immunohistochemical analysis of CBFbeta-SMMHC protein reveals a unique nuclear localization in acute myeloid leukemia with inv(16)(p13q22).
    Zhao W; Claxton DF; Medeiros LJ; Lu D; Vadhan-Raj S; Kantarjian HM; Nguyen MH; Bueso-Ramos CE
    Am J Surg Pathol; 2006 Nov; 30(11):1436-44. PubMed ID: 17063086
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inversion of chromosome 16 and uncommon rearrangements of the CBFB and MYH11 genes in therapy-related acute myeloid leukemia: rare events related to DNA-topoisomerase II inhibitors?
    Dissing M; Le Beau MM; Pedersen-Bjergaard J
    J Clin Oncol; 1998 May; 16(5):1890-6. PubMed ID: 9586906
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CBFβ-SMMHC creates aberrant megakaryocyte-erythroid progenitors prone to leukemia initiation in mice.
    Cai Q; Jeannet R; Hua WK; Cook GJ; Zhang B; Qi J; Liu H; Li L; Chen CC; Marcucci G; Kuo YH
    Blood; 2016 Sep; 128(11):1503-15. PubMed ID: 27443289
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CBFB-SMMHC is correlated with increased calreticulin expression and suppresses the granulocytic differentiation factor CEBPA in AML with inv(16).
    Helbling D; Mueller BU; Timchenko NA; Schardt J; Eyer M; Betts DR; Jotterand M; Meyer-Monard S; Fey MF; Pabst T
    Blood; 2005 Aug; 106(4):1369-75. PubMed ID: 15855281
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv(16)(p13.1q22); CBFβ-MYH11.
    Kanagal-Shamanna R; Zhao W; Vadhan-Raj S; Nguyen MH; Fernandez MH; Medeiros LJ; Bueso-Ramos CE
    Int J Environ Res Public Health; 2012 Aug; 9(8):2788-800. PubMed ID: 23066397
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human CD34+ cells expressing the inv(16) fusion protein exhibit a myelomonocytic phenotype with greatly enhanced proliferative ability.
    Wunderlich M; Krejci O; Wei J; Mulloy JC
    Blood; 2006 Sep; 108(5):1690-7. PubMed ID: 16670269
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Detection of CBFbeta/MYH11 fusion transcripts in patients with inv(16) acute myeloid leukemia after allogeneic bone marrow or peripheral blood progenitor cell transplantation.
    Elmaagacli AH; Beelen DW; Kroll M; Trzensky S; Stein C; Schaefer UW
    Bone Marrow Transplant; 1998 Jan; 21(2):159-66. PubMed ID: 9489633
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantification of CBFbeta/MYH11 fusion transcript by real time RT-PCR in patients with INV(16) acute myeloid leukemia.
    Marcucci G; Caligiuri MA; Döhner H; Archer KJ; Schlenk RF; Döhner K; Maghraby EA; Bloomfield CD
    Leukemia; 2001 Jul; 15(7):1072-80. PubMed ID: 11455976
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice.
    Illendula A; Pulikkan JA; Zong H; Grembecka J; Xue L; Sen S; Zhou Y; Boulton A; Kuntimaddi A; Gao Y; Rajewski RA; Guzman ML; Castilla LH; Bushweller JH
    Science; 2015 Feb; 347(6223):779-84. PubMed ID: 25678665
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia.
    Kuo YH; Landrette SF; Heilman SA; Perrat PN; Garrett L; Liu PP; Le Beau MM; Kogan SC; Castilla LH
    Cancer Cell; 2006 Jan; 9(1):57-68. PubMed ID: 16413472
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia.
    Corces MR; Chang HY; Majeti R
    Front Oncol; 2017; 7():263. PubMed ID: 29164062
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Isolated duodenal myeloid sarcoma associated with the
    Huang B; You P; Zhu P; DU Z; Wu B; Xu X; Chen Z
    Oncol Lett; 2014 Sep; 8(3):1261-1264. PubMed ID: 25120702
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16).
    Markus J; Garin MT; Bies J; Galili N; Raza A; Thirman MJ; Le Beau MM; Rowley JD; Liu PP; Wolff L
    Cancer Res; 2007 Feb; 67(3):992-1000. PubMed ID: 17283131
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice.
    Hyde RK; Zhao L; Alemu L; Liu PP
    Leukemia; 2015 Aug; 29(8):1771-8. PubMed ID: 25742748
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.