114 related articles for article (PubMed ID: 29759988)
1. Transient Telomerase Inhibition with Imetelstat Impacts DNA Damage Signals and Cell-Cycle Kinetics.
Thompson CAH; Gu A; Yang SY; Mathew V; Fleisig HB; Wong JMY
Mol Cancer Res; 2018 Aug; 16(8):1215-1225. PubMed ID: 29759988
[TBL] [Abstract][Full Text] [Related]
2. The HSP90 inhibitor alvespimycin enhances the potency of telomerase inhibition by imetelstat in human osteosarcoma.
Hu Y; Bobb D; He J; Hill DA; Dome JS
Cancer Biol Ther; 2015; 16(6):949-57. PubMed ID: 25920748
[TBL] [Abstract][Full Text] [Related]
3. Effect of telomerase inhibition on preclinical models of malignant rhabdoid tumor.
Hu Y; Bobb D; Lu Y; He J; Dome JS
Cancer Genet; 2014 Sep; 207(9):403-11. PubMed ID: 25441685
[TBL] [Abstract][Full Text] [Related]
4. Short-term treatment with imetelstat sensitizes hematopoietic malignant cells to a genotoxic agent via suppression of the telomerase-mediated DNA repair process.
Hidaka D; Onozawa M; Miyashita N; Yokoyama S; Nakagawa M; Hashimoto D; Teshima T
Leuk Lymphoma; 2020 Nov; 61(11):2722-2732. PubMed ID: 32571117
[TBL] [Abstract][Full Text] [Related]
5. Telomerase inhibitor imetelstat has preclinical activity across the spectrum of non-small cell lung cancer oncogenotypes in a telomere length dependent manner.
Frink RE; Peyton M; Schiller JH; Gazdar AF; Shay JW; Minna JD
Oncotarget; 2016 May; 7(22):31639-51. PubMed ID: 27192120
[TBL] [Abstract][Full Text] [Related]
6. Telomerase inhibition potentiates the effects of genotoxic agents in breast and colorectal cancer cells in a cell cycle-specific manner.
Tamakawa RA; Fleisig HB; Wong JM
Cancer Res; 2010 Nov; 70(21):8684-94. PubMed ID: 20837664
[TBL] [Abstract][Full Text] [Related]
7. Telomerase antagonist imetelstat inhibits esophageal cancer cell growth and increases radiation-induced DNA breaks.
Wu X; Smavadati S; Nordfjäll K; Karlsson K; Qvarnström F; Simonsson M; Bergqvist M; Gryaznov S; Ekman S; Paulsson-Karlsson Y
Biochim Biophys Acta; 2012 Dec; 1823(12):2130-5. PubMed ID: 22906540
[TBL] [Abstract][Full Text] [Related]
8. Telomerase inhibitors and 'T-oligo' as cancer therapeutics: contrasting molecular mechanisms of cytotoxicity.
Rankin AM; Faller DV; Spanjaard RA
Anticancer Drugs; 2008 Apr; 19(4):329-38. PubMed ID: 18454043
[TBL] [Abstract][Full Text] [Related]
9. Telomerase inhibitor Imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cells.
Burchett KM; Yan Y; Ouellette MM
PLoS One; 2014; 9(1):e85155. PubMed ID: 24409321
[TBL] [Abstract][Full Text] [Related]
10. Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs.
Pandita RK; Chow TT; Udayakumar D; Bain AL; Cubeddu L; Hunt CR; Shi W; Horikoshi N; Zhao Y; Wright WE; Khanna KK; Shay JW; Pandita TK
Cancer Res; 2015 Mar; 75(5):858-69. PubMed ID: 25589350
[TBL] [Abstract][Full Text] [Related]
11. DNA damage transiently increases TRF2 mRNA expression and telomerase activity.
Klapper W; Qian W; Schulte C; Parwaresch R
Leukemia; 2003 Oct; 17(10):2007-15. PubMed ID: 14513051
[TBL] [Abstract][Full Text] [Related]
12. ssDNA fragments induce cell senescence by telomere uncapping.
Tsolou A; Passos JF; Nelson G; Arai Y; Zglinicki Tv
Exp Gerontol; 2008 Oct; 43(10):892-9. PubMed ID: 18778766
[TBL] [Abstract][Full Text] [Related]
13. Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways.
Lydall D
J Cell Sci; 2003 Oct; 116(Pt 20):4057-65. PubMed ID: 12972499
[TBL] [Abstract][Full Text] [Related]
14. Protection against chromosome degradation at the telomeres.
Grandin N; Charbonneau M
Biochimie; 2008 Jan; 90(1):41-59. PubMed ID: 17764802
[TBL] [Abstract][Full Text] [Related]
15. DNA-Directed Polymerase Subunits Play a Vital Role in Human Telomeric Overhang Processing.
Diotti R; Kalan S; Matveyenko A; Loayza D
Mol Cancer Res; 2015 Mar; 13(3):402-10. PubMed ID: 25519149
[TBL] [Abstract][Full Text] [Related]
16. The telomerase inhibitor imetelstat alone, and in combination with trastuzumab, decreases the cancer stem cell population and self-renewal of HER2+ breast cancer cells.
Koziel JE; Herbert BS
Breast Cancer Res Treat; 2015 Feb; 149(3):607-18. PubMed ID: 25627551
[TBL] [Abstract][Full Text] [Related]
17. Telomere length homeostasis.
Hug N; Lingner J
Chromosoma; 2006 Dec; 115(6):413-25. PubMed ID: 16741708
[TBL] [Abstract][Full Text] [Related]
18. Targeting Telomere Biology in Acute Lymphoblastic Leukemia.
Karow A; Haubitz M; Oppliger Leibundgut E; Helsen I; Preising N; Steiner D; Dantonello TM; Ammann RA; Roessler J; Kartal-Kaess M; Röth A; Baerlocher GM
Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34206297
[TBL] [Abstract][Full Text] [Related]
19. Telomeres and telomerase.
Chan SR; Blackburn EH
Philos Trans R Soc Lond B Biol Sci; 2004 Jan; 359(1441):109-21. PubMed ID: 15065663
[TBL] [Abstract][Full Text] [Related]
20. Oligonucleotides Targeting Telomeres and Telomerase in Cancer.
Schrank Z; Khan N; Osude C; Singh S; Miller RJ; Merrick C; Mabel A; Kuckovic A; Puri N
Molecules; 2018 Sep; 23(9):. PubMed ID: 30189661
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
